Senecio longibolus

• Index
• Plant Species
• Metabolite list (6)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Senecio longibolus
Genus	Senecio
Family	Asteraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Senecio
Linked NCBI taxonomy ID	18794
Linked level	genus

Family

Family in NCBI taxonomy	Asteraceae
ID	4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (6)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00002092	Integerrimine	CHEMBL362153 CHEMBL488203		8 / 1 / 5		No. 622	No. 2
C00002110	Riddelline		C013672		0 / 15	No. 622	No. 2
C00002116	Senecionine	CHEMBL362153 CHEMBL488203	C009237	8 / 1 / 5	1 / 1	No. 622	No. 2
C00002117	Seneciphylline	CHEMBL523911 CHEMBL1396368 CHEMBL1439490 CHEMBL1591009	C013678	14 / 12 / 13		No. 622	No. 2
C00026228	Seneciphylline oxide / Seneciphylline N-oxide					No. 2356
C00046027	Integerrimine N-oxide	CHEMBL471683				No. 2356

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q01196	Runt-related transcription factor 1	Unclassified protein	C00002092 C00002116 C00002117	1 / 4
Q13951	Core-binding factor subunit beta	Unclassified protein	C00002092 C00002116 C00002117	0 / 1
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00002092 C00002116 C00002117	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002092 C00002116 C00002117	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00002092 C00002116 C00002117	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002092 C00002116 C00002117	0 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00002092 C00002116	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00002092 C00002116	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002117	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002117	1 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00002117	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00002117	7 / 3
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002117	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00002117	2 / 3
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002117	0 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002117	1 / 0

1 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
54657	UGT1A4, HUG-BR2, UDPGT, UDPGT_1-4, UGT-1D, UGT1-04, UGT1.4, UGT1D	UDP glucuronosyltransferase 1 family, polypeptide A4 (EC:2.4.1.17)	C00002116

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions