Senecio aureus
Species
KNApSAcK Entry
| Organism name | Senecio aureus |
|---|---|
| Genus | Senecio |
| Family | Asteraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Packera aurea |
|---|---|
| Linked NCBI taxonomy ID | 98688 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Asteraceae |
|---|---|
| ID | 4210 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Natural Activity
List (20)
| Species | Activity |
|---|---|
| Senecio aureus L. | Abortifacient |
| Senecio aureus L. | Analgesic |
| Senecio aureus L. | Antipyretic |
| Senecio aureus L. | Astringent |
| Senecio aureus L. | Bitter |
| Senecio aureus L. | Carcinogenic |
| Senecio aureus L. | Contraceptive |
| Senecio aureus L. | Depurative |
| Senecio aureus L. | Diaphoretic |
| Senecio aureus L. | Diuretic |
| Senecio aureus L. | Emmenagogue |
| Senecio aureus L. | Expectorant |
| Senecio aureus L. | Hemostat |
| Senecio aureus L. | Hepatotoxic |
| Senecio aureus L. | Litholytic |
| Senecio aureus L. | Pectoral |
| Senecio aureus L. | Stimulant |
| Senecio aureus L. | Tonic |
| Senecio aureus L. | Uterotonic |
| Senecio aureus L. | Vulnerary |
Metabolite list (4)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00002116
|
Senecionine
|
CHEMBL362153
CHEMBL488203 |
C009237
|
8 / 1 / 5 | 1 / 1 | No. 622 | No. 2 |
|
|
C00017336
|
Tetrahydroligularenolide
|
No. 1441 | No. 38 |
|
||||
|
C00017405
|
[4aR-(4aalpha,5alpha,8abeta,9abeta)]-9a-Ethoxy-4a,5,6,7,8,8a,9,9a-octahydro-3,4a,5-trimethyl-naphtho[2,3-b]furan-2(4H)-one
|
No. 1441 | No. 38 |
|
||||
|
C00017376
|
8,12-Epoxy-10alpha-Eremophila-7,11-dien-9-one
|
No. 2598 |
|
Human Protein / Gene in interactions
8 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P39748 | Flap endonuclease 1 | Enzyme | C00002116 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002116 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002116 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00002116 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00002116 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00002116 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00002116 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00002116 | 1 / 4 |
1 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 54657 | UGT1A4, HUG-BR2, UDPGT, UDPGT_1-4, UGT-1D, UGT1-04, UGT1.4, UGT1D | UDP glucuronosyltransferase 1 family, polypeptide A4 (EC:2.4.1.17) |
C00002116
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (1)
| OMIM | preferred title | UniProt |
|---|---|---|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
KEGG DISEASE (5)
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|