PCIDB

Cinchona tucujensis

Species

KNApSAcK Entry

Organism name Cinchona tucujensis
Genus Cinchona
Family Rubiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Cinchona
Linked NCBI taxonomy ID 43462
Linked level genus

Family

Family in NCBI taxonomy Rubiaceae
ID 24966

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00002147 External link 512 Cinchonidine
CHEMBL15134
CHEMBL461234
CHEMBL518804
CHEMBL533841
CHEMBL588619
CHEMBL611480
CHEMBL1414315
CHEMBL1477170
CHEMBL1590546
CHEMBL2079612
CHEMBL2357353
C041622
13 / 10 / 8 No. 1378 No. 7

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002147 1 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00002147 3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002147 0 / 1
O75496 Geminin Unclassified protein C00002147 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00002147 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00002147 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002147 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002147 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002147 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00002147 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00002147 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002147 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00002147 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#600274 Frontotemporal dementia; ftd P10636
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (8)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)