Organism name | Dictamnus dasycarpus |
---|---|
Genus | Dictamnus |
Family | Rutaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Dictamnus dasycarpus |
---|---|
Linked NCBI taxonomy ID | 714465 |
Linked level | species |
Family in NCBI taxonomy | Rutaceae |
---|---|
ID | 23513 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | rosids |
---|---|
ID | 71275 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00029585
![]() |
Ikshusterol
/ 7alpha-Hydroxysitosterol / Stigmast-5-ene-3beta,7alpha-diol / (-)-Stigmast-5-ene-3beta,7alpha-diol |
CHEMBL455367
|
C011486
|
No. 53 | No. 11 |
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||
C00045842
![]() |
Dictamnoside B
/ (-)-Dictamnoside B |
No. 191 |
![]() |
|||||
C00045846
![]() |
Dictamnoside I
/ (-)-Dictamnoside I |
No. 191 |
![]() |
|||||
C00045847
![]() |
Dictamnoside J
|
No. 191 |
![]() |
|||||
C00045848
![]() |
Dictamnoside K
/ (-)-Dictamnoside K |
No. 191 |
![]() |
|||||
C00045845
![]() |
Dictamnoside H
/ (-)-Dictamnoside H |
No. 191 |
![]() |
|||||
C00045843
![]() |
Dictamnoside D
/ (-)-Dictamnoside D |
No. 191 |
![]() |
|||||
C00045841
![]() |
Dictamnoside A
/ (-)-Dictamnoside A |
CHEMBL471091
|
No. 191 |
![]() |
||||
C00003719
![]() |
Limonin
|
CHEMBL1523286
CHEMBL1886762 CHEMBL1897224 CHEMBL2004366 |
C001546
|
2 / 0 / 1 | 1 / 1 | No. 204 | No. 51 |
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C00003727
![]() |
Rutaevin
|
CHEMBL402437
|
C079993
|
No. 204 | No. 51 |
![]() |
||
C00003723
![]() |
Obacunone
|
CHEMBL404140
|
C067207
|
1 / 0 / 0 | 8 / 0 | No. 204 | No. 51 |
![]() |
C00030241
![]() |
Evodol
/ Limonin diosphenol |
CHEMBL521514
|
No. 204 | No. 51 |
![]() |
|||
C00026468
![]() |
O-Ethylnordictamnine
|
No. 368 | No. 7 |
![]() |
||||
C00002172
![]() |
Haplopine
|
CHEMBL455007
|
C012345
|
3 / 8 / 3 | No. 368 | No. 7 |
![]() |
|
C00002151
![]() |
Dictamine
/ Dictamnine |
CHEMBL22533
|
C026398
|
No. 368 | No. 7 |
![]() |
||
C00026444
![]() |
Iso-gamma-fagarine
|
CHEMBL447997
|
6 / 2 / 2 | No. 624 | No. 7 |
![]() |
||
C00026447
![]() |
Isomaculosidine
/ 6,8-dimethoxydictamnine |
No. 624 | No. 7 |
![]() |
||||
C00026416
![]() |
Dictangustine A
|
No. 624 | No. 7 |
![]() |
||||
C00026476
![]() |
Preskimmianine
|
CHEMBL487794
|
No. 781 |
![]() |
||||
C00039016
![]() |
Dictamdiol B
|
CHEMBL403868
CHEMBL404868 CHEMBL256353 |
No. 1461 |
![]() |
||||
C00030125
![]() |
Dictamdiol
|
CHEMBL403868
CHEMBL404868 CHEMBL256353 |
No. 1461 |
![]() |
||||
C00039015
![]() |
Dictamdiol A
|
CHEMBL403868
CHEMBL404868 CHEMBL256353 |
No. 1461 |
![]() |
||||
C00011939
![]() |
Fraxinellone
|
CHEMBL257170
CHEMBL1595442 |
C075391
|
3 / 5 / 4 | No. 1461 |
![]() |
||
C00036671
![]() |
9beta-Hydroxyfraxinellone
/ (-)-9beta-Hydroxyfraxinellone |
CHEMBL257169
|
No. 1461 |
![]() |
||||
C00026361
![]() |
Platydesmine
/ (+)-Platydesmine |
No. 1467 | No. 7 |
![]() |
||||
C00026371
![]() |
7,8-Dimethoxyplatydesmine
/ (2S)-(-)-7,8-Dimethoxyplatydesmine |
CHEMBL463650
|
No. 1467 | No. 7 |
![]() |
|||
C00045850
![]() |
Dictamnoside M
/ (-)-Dictamnoside M |
No. 1553 |
![]() |
|||||
C00045844
![]() |
Dictamnoside G
|
No. 1553 |
![]() |
|||||
C00049147
![]() |
Dictamnol
/ (+)-Dictamnol |
No. 1952 |
![]() |
|||||
C00038681
![]() |
Calodendrolide
|
CHEMBL256319
|
No. 1964 |
![]() |
||||
C00049184
![]() |
Isofraxinellone
|
No. 1964 |
![]() |
|||||
C00031626
![]() |
beta-Elemol
|
No. 2406 |
![]() |
|||||
C00045851
![]() |
Dictamnoside N
/ (-)-Dictamnoside N |
No. 3590 |
![]() |
|||||
C00026398
![]() |
7,8-Dimethoxymyrtopsine
/ (+)-7,8-Dimethoxymyrtopsine |
CHEMBL463651
|
No. 4151 |
![]() |
||||
C00045849
![]() |
Dictamnoside L
/ (-)-Dictamnoside L |
No. 4164 |
![]() |
|||||
C00030329
![]() |
Fraxinellonone
|
CHEMBL403869
|
No. 8112 |
![]() |
||||
C00039017
![]() |
Dictamnusine
|
CHEMBL402945
|
No. 8190 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002172 C00026444 | 0 / 0 |
P83916 | Chromobox protein homolog 1 | Unclassified protein | C00026444 | 0 / 0 |
P16473 | Thyrotropin receptor | Glycohormone receptor | C00011939 | 3 / 2 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00026444 | 0 / 0 |
O75496 | Geminin | Unclassified protein | C00026444 | 0 / 0 |
P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00026444 | 0 / 0 |
P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00002172 | 7 / 3 |
P55789 | FAD-linked sulfhydryl oxidase ALR | Enzyme | C00002172 | 1 / 0 |
P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00026444 | 2 / 2 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00003723 | 0 / 0 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003719 | 0 / 1 |
P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00011939 | 1 / 1 |
P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00003719 | 0 / 0 |
Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00011939 | 1 / 1 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00003719
|
581 | BAX, BCL2L4 | BCL2-associated X protein |
C00003723
|
596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00003723
|
836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00003723
|
841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00003723
|
842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00003723
|
5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00003723
|
5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00003723
|
7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00003723
|
OMIM | preferred title | UniProt |
---|---|---|
#219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
#612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
#119900 | Digital clubbing, isolated congenital |
P15428
|
#232300 | Glycogen storage disease ii |
P10253
|
#603373 | Hyperthyroidism, familial gestational |
P16473
|
#609152 | Hyperthyroidism, nonautoimmune |
P16473
|
#259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
#275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
#174800 | Mccune-albright syndrome; mas |
P63092
|
#613076 | Myopathy, mitochondrial progressive, with congenital cataract, hearing loss, and developmental delay |
P55789
|
#166350 | Osseous heteroplasia, progressive; poh |
P63092
|
#102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
#103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
#603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
#612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
KEGG | name | UniProt |
---|---|---|
H00036 | Osteosarcoma |
P08684
(marker)
|
H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
H01269 | Congenital hyperthyroidism |
P16473
(related)
|
H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|