Species

KNApSAcK Entry

Organism name Monnieria trifolia
Genus Monnieria
Family Rutaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Rutaceae
Linked NCBI taxonomy ID 23513
Linked level family

Family

Family in NCBI taxonomy Rutaceae
ID 23513

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00026415 External link 512 Delbine
/ Delbine (Monnieria)
No. 368 No. 7
C00002172 External link 512 Haplopine
CHEMBL455007
C012345
3 / 8 / 3 No. 368 No. 7
C00002158 External link 512 Evoxine
/ 7-(2,3-Dihydroxy-3-methyl-butyl)oxy-8-methyldictamnine
CHEMBL1317300
CHEMBL1395597
CHEMBL1416006
14 / 9 / 9 No. 600 No. 7
C00026463 External link 512 Nkolbisine
/ Montrifoline
/ (-)-Nkolbisine
/ (-)-Montrifoline
No. 600 No. 7

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002158 C00002172 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002158 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00002158 0 / 0
P55789 FAD-linked sulfhydryl oxidase ALR Enzyme C00002172 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002158 0 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00002158 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00002158 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00002172 7 / 3
P10253 Lysosomal alpha-glucosidase Hydrolase C00002158 1 / 1
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00002158 3 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00002158 2 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00002158 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002158 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002158 0 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002158 1 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00002158 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (17)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#137800 Glioma susceptibility 1; glm1 O75874
#232300 Glycogen storage disease ii P10253
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#174800 Mccune-albright syndrome; mas P63092
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#613076 Myopathy, mitochondrial progressive, with congenital cataract, hearing loss, and developmental delay P55789
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092

KEGG DISEASE (12)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H01205 Coumarin resistance P11712 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)