Species

KNApSAcK Entry

Organism name Solanum spp.
Genus Solanum
Family Solanaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Solanum
Linked NCBI taxonomy ID 4107
Linked level genus

Family

Family in NCBI taxonomy Solanaceae
ID 4070

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (20)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005556 External link 512 Isorhamnetin 3,7-diglucoside
/ Isorhamnetin 3,7-di-O-beta-glucopyranoside
No. 1 No. 15
C00005412 External link 512 Quercetin 3-neohesperidoside
/ Quercetin 3-O-neohesperidoside
CHEMBL499824
No. 1 No. 15
C00005409 External link 512 Quercetin 3-O-sophoroside
CHEMBL452919
C055545
No. 1 No. 15
C00005182 External link 512 Kaempferol 3,7-diglucoside
/ Kaempferol 3,7-O-beta-D-diglucopyranoside
CHEMBL2206209
No. 1 No. 15
C00005165 External link 512 Sophoraflavonoloside
/ Kaempferol 3-O-sophoroside
/ Kaempferol 3-O-beta-sophoroside
CHEMBL500233
CHEMBL1375795
CHEMBL2032411
C064309
12 / 2 / 2 6 / 4 No. 1 No. 15
C00005167 External link 512 Kaempferol 3-neohesperidoside
CHEMBL507493
No. 1 No. 15
C00005178 External link 512 Kaempferol 3-galactoside-7-rhamnoside
CHEMBL1929192
CHEMBL1929193
2 / 0 / 0 No. 1 No. 15
C00005425 External link 512 Quercetin 3-galactoside-7-rhamnoside
CHEMBL592361
CHEMBL1774171
No. 1 No. 15
C00005370 External link 512 Reynoutrin
CHEMBL183031
CHEMBL185461
CHEMBL488198
CHEMBL464507
CHEMBL520637
No. 2 No. 15
C00005491 External link 512 Quercetin 3-methyl ether 7-glucoside
/ 3-O-Methylquercetin 7-O-beta-D-glucopyranoside
CHEMBL260805
CHEMBL574682
1 / 0 / 3 No. 2 No. 15
C00005264 External link 512 Isokaempferide 7-glucoside
CHEMBL1689265
1 / 0 / 3 No. 2 No. 15
C00004759 External link 512 Annulatin
No. 3 No. 15
C00005456 External link 512 Manghaslin
/ Quercetin 3-2G-rhamnosylrutinoside
CHEMBL444468
No. 5 No. 15
C00005483 External link 512 Quercetin 3-glucoside-7-rutinoside
No. 5 No. 15
C00005219 External link 512 Clitorin
/ Kaempferol 3-(2G-rhamnosylrutinoside)
CHEMBL362593
CHEMBL1454324
CHEMBL2005346
C077190
1 / 0 / 0 No. 5 No. 15
C00005217 External link 512 Kaempferol 3-(2G-glucosylrutinoside)
/ Kaempferol 3-(6'''-rhamnosyl-2'''-glucosyl-glucoside)
No. 5 No. 15
C00005230 External link 512 Kaempferol 3-sophoroside-7-rhamnoside
No. 5 No. 15
C00002268 External link 512 Tomatine
CHEMBL525778
CHEMBL2007040
D014053
No. 21 No. 11
C00002716 External link 512 Caffeic acid 3-glucoside
No. 662
C00002718 External link 512 1-Caffeoyl-beta-D-glucose
CHEMBL482242
No. 1127 No. 6

Human Protein / Gene in interactions

15 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00005264 C00005491 0 / 3
P11387 DNA topoisomerase 1 Isomerase C00005178 C00005219 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00005165 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00005165 0 / 0
P06746 DNA polymerase beta Enzyme C00005165 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00005178 0 / 0
P39748 Flap endonuclease 1 Enzyme C00005165 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00005165 1 / 1
O75496 Geminin Unclassified protein C00005165 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00005165 1 / 1
Q9UNA4 DNA polymerase iota Enzyme C00005165 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00005165 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00005165 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00005165 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00005165 0 / 0

6 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
3146 HMGB1, HMG1, HMG3, SBP-1 high mobility group box 1 C00005165
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00005165
6401 SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 selectin E C00005165
7097 TLR2, CD282, TIL4 toll-like receptor 2 C00005165
7099 TLR4, ARMD10, CD284, TLR-4, TOLL toll-like receptor 4 C00005165
7412 VCAM1, CD106, INCAM-100 vascular cell adhesion molecule 1 C00005165

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#232300 Glycogen storage disease ii P10253
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (5)

KEGG name UniProt
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

4 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003920 Diabetes Mellitus C00005165
D006967 Hypersensitivity C00005165
D007249 Inflammation C00005165
D009369 Neoplasms C00005165