Species

KNApSAcK Entry

Organism name Evolvulus sericeus
Genus Evolvulus
Family Convolvulaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Evolvulus sericeus
Linked NCBI taxonomy ID 113201
Linked level species

Family

Family in NCBI taxonomy Convolvulaceae
ID 4118

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002287 External link 512 Convolamine
CHEMBL1514821
CHEMBL1907009
5 / 2 / 3 No. 1355 No. 1
C00002288 External link 512 Convoline
CHEMBL1890337
1 / 0 / 0 No. 1355 No. 1
C00036930 External link 512 Convolidine
CHEMBL1384086
5 / 3 / 7 No. 1355 No. 1

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002287 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002287 0 / 1
O75496 Geminin Unclassified protein C00002288 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002287 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002287 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002287 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00036930 0 / 0
O00167 Eyes absent homolog 2 Enzyme C00036930 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00036930 0 / 0
O00255 Menin Unclassified protein C00036930 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00036930 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255

KEGG DISEASE (10)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)