Species

KNApSAcK Entry

Organism name Impatiens balsamina
Genus Impatiens
Family Balsaminaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Impatiens balsamina
Linked NCBI taxonomy ID 63779
Linked level species

Family

Family in NCBI taxonomy Balsaminaceae
ID 25692

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (10)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002384 External link 512 Malvin
/ Malvidin diglucoside
/ Malvidin 3,5-diglucoside
CHEMBL2009656
No. 1 No. 15
C00002387 External link 512 Pelargonin
/ Pelargonidin 3,5-di-beta-D-glucoside
No. 1 No. 15
C00006698 External link 512 Myrtillin
/ Delphinidin 3-O-beta-D-glucopyranoside
CHEMBL518846
No. 2 No. 15
C00006630 External link 512 Callistephin
/ Pelargonidin 3-O-beta-D-glucopyranoside
C078485
No. 2 No. 15
C00005213 External link 512 Kaempferol 3-(3G-glucosylneohesperidoside)
/ Kaempferol 3-rhamnosyl-(1->2)-[glucosyl-(1->3)-glucoside]
/ 3-[(O-6-Deoxy-alpha-L-mannopyranosyl-(1->2)-O-[beta-D-glucopyranosyl-(1->3)]-beta-D-glucopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
No. 5 No. 15
C00002837 External link 512 Lawsone
CHEMBL240963
C005090
16 / 12 / 13 1 / 3 No. 1047 No. 80
C00049940 External link 512 2-Methoxy-1,4-naphthoquinone
CHEMBL106562
C096118
13 / 5 / 5 No. 1047 No. 80
C00002674 External link 512 Syringic acid
/ 4-Hydroxy-3,5-dimethoxybenzoic acid
CHEMBL1414
C001945
12 / 3 / 5 No. 1073
C00050009 External link 512 Balsaminone A
No. 5829
C00050010 External link 512 Balsaminone B
CHEMBL463739
No. 6510

Human Protein / Gene in interactions

40 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P14902 Indoleamine 2,3-dioxygenase 1 Enzyme C00002837 C00049940 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00049940 1 / 1
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00002674 0 / 0
P43166 Carbonic anhydrase 7 Lyase C00002674 0 / 0
P22894 Neutrophil collagenase M10A C00002837 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00002837 2 / 2
P00918 Carbonic anhydrase 2 Lyase C00002674 1 / 2
P11473 Vitamin D3 receptor NR1I1 C00002837 2 / 3
P23280 Carbonic anhydrase 6 Lyase C00002674 0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00002674 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002837 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00002674 1 / 2
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00002837 0 / 0
P39748 Flap endonuclease 1 Enzyme C00049940 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00049940 2 / 0
O75496 Geminin Unclassified protein C00049940 0 / 0
P15121 Aldose reductase Enzyme C00002674 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00002674 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00049940 0 / 0
P03956 Interstitial collagenase M10A C00002837 0 / 1
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00002674 0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00049940 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00002837 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00002837 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00002674 0 / 1
P08253 72 kDa type IV collagenase M10A C00002837 1 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00002837 2 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00049940 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002837 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00049940 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00002837 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00049940 0 / 0
P07451 Carbonic anhydrase 3 Lyase C00002674 0 / 0
P08254 Stromelysin-1 M10A C00002837 1 / 0
P22748 Carbonic anhydrase 4 Lyase C00002674 1 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00002837 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002837 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00049940 1 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00049940 0 / 3
Q13148 TAR DNA-binding protein 43 Unclassified protein C00049940 1 / 1

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
196 AHR, bHLHe76 aryl hydrocarbon receptor C00002837

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (20)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#114500 Colorectal cancer; crc P84022
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#119900 Digital clubbing, isolated congenital P15428
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#143860 Hyperchlorhidrosis, isolated O43570
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#603932 Intervertebral disc disease; idd P14780
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#600852 Retinitis pigmentosa 17; rp17 P22748
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (22)

KEGG name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00028 Choriocarcinoma P03956 (related)
P08253 (related)
H00025 Penile cancer P08253 (related)
P14780 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

3 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D005533 Foot Dermatoses C00002837
D006229 Hand Dermatoses C00002837
D010292 Paresthesia C00002837