Dorstenia gigas
Species
KNApSAcK Entry
| Organism name | Dorstenia gigas |
|---|---|
| Genus | Dorstenia |
| Family | Moraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Dorstenia |
|---|---|
| Linked NCBI taxonomy ID | 106722 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Moraceae |
|---|---|
| ID | 3487 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (9)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00002453
|
Byakangelicin
/ (+)-Byakangelicin |
CHEMBL508648
|
C434685
|
5 / 2 / 0 | No. 579 | No. 25 |
|
|
|
C00036625
|
6-Methoxy-5-(3-methyl-2,3-dihydroxybutyl)-angelicin
|
No. 579 | No. 25 |
|
||||
|
C00036590
|
5,8-Dimethoxy-3-(3-methyl-2,3-dihydroxybutyl)-psoralen
/ (-)-5,8-Dimethoxy-3-(3-methyl-2,3-dihydroxybutyl)-psoralen |
No. 579 | No. 25 |
|
||||
|
C00036599
|
5-Methoxy-8-(1,1-dimethyl-2,3-dihydroxypropyl)-psoralen
/ (+)-5-Methoxy-8-(1,1-dimethyl-2,3-dihydroxypropyl)-psoralen |
No. 579 | No. 25 |
|
||||
|
C00032846
|
Cnidilin
/ Knidilin / Isophellopterin |
CHEMBL1934194
|
1 / 0 / 0 | No. 606 | No. 25 |
|
||
|
C00030532
|
Isoimperatorin
|
CHEMBL448060
|
C055542
|
8 / 13 / 11 | 3 / 1 | No. 606 | No. 25 |
|
|
C00037872
|
Swietenocoumarin B
|
No. 606 | No. 25 |
|
||||
|
C00037065
|
Dorstegin
|
No. 750 | No. 25 |
|
||||
|
C00037165
|
Furopinnarin
|
No. 3930 | No. 25 |
|
Human Protein / Gene in interactions
12 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P56817 | Beta-secretase 1 | A1A | C00002453 C00030532 C00032846 | 0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00030532 | 1 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00002453 | 1 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00030532 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00002453 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00030532 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00030532 | 11 / 10 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00030532 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002453 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00030532 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002453 | 1 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00030532 | 1 / 1 |
3 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00030532
|
| 2939 | GSTA2, GST2, GSTA2-2, GTA2, GTH2 | glutathione S-transferase alpha 2 (EC:2.5.1.18) |
C00030532
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00030532
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (15)
| OMIM | preferred title | UniProt |
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (11)
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|