| Organism name | Cladrastis platycarpa |
|---|---|
| Genus | Cladrastis |
| Family | Fabaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Cladrastis platycarpa |
|---|---|
| Linked NCBI taxonomy ID | 247908 |
| Linked level | species |
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | rosids |
|---|---|
| ID | 71275 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00006176
|
Vicenin 1
|
No. 1 | No. 15 |
|
||||
|
C00010095
|
8-O-Methylretusin 7-O-glucoside
|
No. 2 | No. 15 |
|
||||
|
C00010135
|
Platycarpanetin 7-O-glucoside
|
No. 2 | No. 15 |
|
||||
|
C00010085
|
Rothindin
/ Pseudobaptigenin 7-O-glucoside |
No. 2 | No. 15 |
|
||||
|
C00009400
|
8-O-Methylretusin
|
CHEMBL477720
|
No. 3 | No. 15 |
|
|||
|
C00006083
|
Bayin
/ 8-beta-D-Glucopyranosyl-4',7-dihydroxyflavone |
No. 22 | No. 15 |
|
||||
|
C00009406
|
Fujikinetin
/ 7-Hydroxy-6-methoxy-3',4'-methylenedioxyisoflavone |
CHEMBL485985
|
No. 27 | No. 15 |
|
|||
|
C00002565
|
Pseudobaptigenin
|
CHEMBL486176
|
C060800
|
3 / 5 / 3 | No. 27 | No. 15 |
|
|
|
C00009478
|
Platycarpanetin
|
No. 27 | No. 15 |
|
||||
|
C00009476
|
Dipteryxine
/ Isoplatycarpanetin / 7-Hydroxy-5,6-dimethoxy-3',4'-methylenedioxyisoflavone |
No. 27 | No. 15 |
|
||||
|
C00009415
|
Cladrastin
|
No. 35 | No. 15 |
|
||||
|
C00009470
|
5-Methoxyafrormosin
/ 7-Hydroxy-5,6,4'-trimethoxyisoflavone |
CHEMBL457449
|
No. 35 | No. 15 |
|
|||
|
C00009471
|
Iso-5-methoxyafrormosin
/ 7-Hydroxy-5,8,4'-trimethoxyisoflavone |
No. 35 | No. 15 |
|
||||
|
C00002507
|
Castanin
/ Afromosin / Afrormosin / 7-Hydroxy-6,4'-dimethoxyisoflavone |
CHEMBL464404
|
C080240
|
7 / 14 / 39 | 1 / 0 | No. 35 | No. 15 |
|
|
C00009398
|
Cladrin
/ 7-Hydroxy-3',4'-dimethoxyisoflavone |
CHEMBL454746
|
13 / 31 / 49 | No. 35 | No. 15 |
|
||
|
C00010008
|
2-Hydroxymaackiain
/ 2,3-Dihydroxy-8,9-methylenedioxypterocarpan |
CHEMBL455617
|
No. 66 | No. 15 |
|
|||
|
C00006114
|
3'-C-Glucosylisoliquiritigenin
|
No. 3678 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00002507 C00009398 | 7 / 37 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00002507 C00009398 | 0 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00002565 C00009398 | 5 / 3 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00002507 C00009398 | 4 / 2 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00002507 C00009398 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00009398 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00009398 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00009398 | 7 / 3 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00002507 | 2 / 2 |
| O75496 | Geminin | Unclassified protein | C00002507 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00009398 | 3 / 3 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00009398 | 1 / 1 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00002565 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00009398 | 4 / 3 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00002565 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00009398 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002507 | 1 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00009398 | 0 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00002507
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| %606641 | Body mass index; bmi |
P37231
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #133239 | Esophageal cancer |
P04637
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P37231 |
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #211980 | Lung cancer |
P04637
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P37231
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #167000 | Ovarian cancer |
P38398
|
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00026 | Endometrial Cancer |
P04637
(related)
|
| H00027 | Ovarian cancer |
P04637
(related)
P38398 (related) |
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
P38398 (related) |
| H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
| H00033 | Adrenal carcinoma |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
|
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P37231
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|