Species

KNApSAcK Entry

Organism name Podocarpus macrophyllus
Genus Podocarpus
Family Podocarpaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Podocarpus macrophyllus
Linked NCBI taxonomy ID 58043
Linked level species

Family

Family in NCBI taxonomy Podocarpaceae
ID 3362

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Spermatophyta
ID 58024

Metabolite list (13)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00006490 External link 512 Podocarpusflavone A
CHEMBL220745
C094150
2 / 1 / 2 No. 34 No. 18
C00006492 External link 512 Putraflavone
/ Podocarpusflavone B
CHEMBL144630
1 / 0 / 0 No. 34 No. 18
C00006536 External link 512 Cryptomerin A
No. 34 No. 18
C00006534 External link 512 Neocryptomerin
No. 34 No. 18
C00001098 External link 512 Sciadopitysin
CHEMBL208908
C086243
3 / 3 / 7 No. 34 No. 18
C00001049 External link 512 Hinokiflavone
CHEMBL291426
C060299
2 / 1 / 2 No. 34 No. 18
C00039714 External link 512 Makisterone A
CHEMBL255034
1 / 0 / 1 No. 58 No. 11
C00003660 External link 512 Makisterone B
No. 58 No. 11
C00000281 External link 512 Inumakilactone B
No. 463 No. 41
C00000280 External link 512 Inumakilactone A
No. 463 No. 41
C00003441 External link 512 Inumakilactone A glycoside
No. 4689 No. 41
C00000282 External link 512 Inumakilactone C
No. 4930
C00000283 External link 512 Inumakilactone D
No. 4930

Human Protein / Gene in interactions

5 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P56817 Beta-secretase 1 A1A C00001049 C00001098 C00006490 C00006492 0 / 0
P43235 Cathepsin K C1A C00001049 C00006490 1 / 2
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00039714 0 / 1
O00255 Menin Unclassified protein C00001098 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001098 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#265800 Pycnodysostosis P43235

KEGG DISEASE (10)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00273 Pycnodysostosis P43235 (related)
H00425 Lysosomal cysteine protease deficiencies P43235 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)