Organism name | Deguelia hatschbachii |
---|---|
Genus | Deguelia |
Family | Fabaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Deguelia hatschbachii |
---|---|
Linked NCBI taxonomy ID | 132437 |
Linked level | species |
Family in NCBI taxonomy | Fabaceae |
---|---|
ID | 3803 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | rosids |
---|---|
ID | 71275 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00002555
![]() |
Osajin
|
CHEMBL238188
|
36 / 50 / 70 | No. 18 | No. 15 |
![]() |
||
C00009518
![]() |
Nallanin
/ Scandinone |
No. 18 | No. 15 |
![]() |
||||
C00003749
![]() |
Lupeol
/ Lupenol / (+)-Lupenol |
CHEMBL289191
CHEMBL459702 |
C010480
|
3 / 0 / 0 | 2 / 6 | No. 23 | No. 51 |
![]() |
C00008263
![]() |
5,4'-Dihydroxy-7-methoxy-6-C-prenylflavanone
|
No. 28 | No. 14 |
![]() |
||||
C00008262
![]() |
Lupinifolin
|
CHEMBL559980
|
No. 39 |
![]() |
||||
C00019161
![]() |
2'-(3,3-Dimethylallyl)-2'',2''-dimethylchromene (5'',6'':4',3')-4-hydroxy-5'-methoxy stilbene
|
No. 186 |
![]() |
|||||
C00009787
![]() |
Robustic acid
|
CHEMBL400777
|
C105206
|
11 / 26 / 54 | No. 377 |
![]() |
||
C00009788
![]() |
Methyl robustate
/ O-Methylrobustic acid / Robustic acid methyl ether |
No. 377 |
![]() |
|||||
C00019160
![]() |
4,4'-Dihydroxy-3-(3,3-dimethylallyl)-2'',2''-dimethylchromene(5'',6'':5,4)-2-methoxy-8-(propyl-2-one) deoxybenzoin
|
No. 893 |
![]() |
|||||
C00019159
![]() |
6,4'-Dihydroxy-3-(3,3-dimethylallyl)-2'',2''-dimethylchromene(5'',6'':5,4)-2-methoxy deoxybenzoin
|
No. 893 |
![]() |
|||||
C00019162
![]() |
3',5-Dimethoxy-4-hydroxy-4'-(3,3-dimethylallyl) stilbene
|
No. 1271 | No. 13 |
![]() |
||||
C00009792
![]() |
Scandenin
|
CHEMBL1603825
|
9 / 6 / 8 | No. 2734 | No. 16 |
![]() |
||
C00019158
![]() |
3-(4'-Hydroxyphenyl)-5-methoxy-6-(3,3-dimethylallyl)-2'',2''-dimethylchromene-(5'',6'':8,7)-3-(propyl-2-one)-4H-1-benzo-2,3-dihydropyran-2,4-dione
|
No. 6294 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P00352 | Retinal dehydrogenase 1 | Enzyme | C00002555 C00009787 C00009792 | 0 / 0 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002555 C00009787 C00009792 | 0 / 1 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00002555 C00009787 | 4 / 3 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00009787 C00009792 | 0 / 0 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00002555 C00009792 | 0 / 0 |
P04062 | Glucosylceramidase | Enzyme | C00002555 C00009787 | 6 / 4 |
O00255 | Menin | Unclassified protein | C00002555 C00009787 | 2 / 5 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002555 C00009787 | 1 / 2 |
O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00002555 C00009787 | 0 / 0 |
Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00009787 C00009792 | 3 / 3 |
O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00002555 C00009792 | 0 / 0 |
P04637 | Cellular tumor antigen p53 | Transcription Factor | C00002555 C00009787 | 7 / 37 |
P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00002555 | 0 / 0 |
P11388 | DNA topoisomerase 2-alpha | Isomerase | C00003749 | 0 / 0 |
P11473 | Vitamin D3 receptor | NR1I1 | C00009792 | 2 / 3 |
P10828 | Thyroid hormone receptor beta | NR1A2 | C00009787 | 3 / 1 |
P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00002555 | 2 / 2 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00009792 | 0 / 0 |
P42858 | Huntingtin | Unclassified protein | C00002555 | 1 / 1 |
P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00002555 | 2 / 0 |
O75496 | Geminin | Unclassified protein | C00002555 | 0 / 0 |
P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00002555 | 4 / 2 |
P11387 | DNA topoisomerase 1 | Isomerase | C00003749 | 0 / 0 |
Q9Y253 | DNA polymerase eta | Enzyme | C00002555 | 1 / 1 |
P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00002555 | 0 / 0 |
P08047 | Transcription factor Sp1 | Unclassified protein | C00003749 | 0 / 0 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00002555 | 0 / 0 |
P02545 | Prelamin-A/C | Unclassified protein | C00002555 | 11 / 10 |
P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00002555 | 0 / 0 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00002555 | 0 / 0 |
Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00002555 | 1 / 0 |
O75164 | Lysine-specific demethylase 4A | Enzyme | C00002555 | 0 / 0 |
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00002555 | 0 / 0 |
P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00002555 | 1 / 1 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00002555 | 0 / 0 |
P06746 | DNA polymerase beta | Enzyme | C00002555 | 0 / 0 |
Q99700 | Ataxin-2 | Unclassified protein | C00002555 | 1 / 1 |
O00167 | Eyes absent homolog 2 | Enzyme | C00002555 | 0 / 0 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00002555 | 0 / 0 |
Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00009792 | 1 / 1 |
O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002555 | 1 / 0 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00002555 | 0 / 0 |
Q16637 | Survival motor neuron protein | Unclassified protein | C00002555 | 4 / 1 |
P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00002555 | 0 / 3 |
Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00002555 | 1 / 1 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
1499 | CTNNB1, CTNNB, MRD19, armadillo | catenin (cadherin-associated protein), beta 1, 88kDa |
C00003749
|
5728 | PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 | phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) |
C00003749
|
OMIM | preferred title | UniProt |
---|---|---|
#300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
#202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
#612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
#608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
#614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
#114480 | Breast cancer |
P38398
|
#604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
#115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
#212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
#605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
#114500 | Colorectal cancer; crc |
P84022
|
#181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
#133239 | Esophageal cancer |
P04637
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#608013 | Gaucher disease, perinatal lethal |
P04062
|
#230800 | Gaucher disease, type i |
P04062
|
#230900 | Gaucher disease, type ii |
P04062
|
#231000 | Gaucher disease, type iii |
P04062
|
#231005 | Gaucher disease, type iiic |
P04062
|
#137800 | Glioma susceptibility 1; glm1 |
O75874
|
#232300 | Glycogen storage disease ii |
P10253
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#610140 | Heart-hand syndrome, slovenian type |
P02545
|
#143100 | Huntington disease; hd |
P42858
|
#176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
#151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
#613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
#211980 | Lung cancer |
P04637
|
#248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
#300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
#300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
#159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
#607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
#257200 | Niemann-pick disease, type a |
P17405
|
#607616 | Niemann-pick disease, type b |
P17405
|
#167000 | Ovarian cancer |
P38398
|
#614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
#260500 | Papilloma of choroid plexus; cpp |
P04637
|
#168600 | Parkinson disease, late-onset; pd |
P04062
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#275210 | Restrictive dermopathy, lethal |
P02545
|
#253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
#253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
#253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
#271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
#183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
#607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
#275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
#277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
#278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
H00082 | Graves' disease |
P01215
(marker)
|
H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
|
H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
H00663 | Restrictive dermopathy |
P02545
(related)
|
H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
H00126 | Gaucher disease |
P04062
(related)
|
H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
H00006 | Hairy-cell leukemia |
P04637
(related)
|
H00008 | Burkitt lymphoma |
P04637
(related)
|
H00009 | Adult T-cell leukemia |
P04637
(related)
|
H00010 | Multiple myeloma |
P04637
(related)
|
H00013 | Small cell lung cancer |
P04637
(related)
|
H00014 | Non-small cell lung cancer |
P04637
(related)
|
H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
H00018 | Gastric cancer |
P04637
(related)
|
H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
H00022 | Bladder cancer |
P04637
(related)
|
H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
H00026 | Endometrial Cancer |
P04637
(related)
|
H00027 | Ovarian cancer |
P04637
(related)
P38398 (related) |
H00028 | Choriocarcinoma |
P04637
(related)
|
H00029 | Vulvar cancer |
P04637
(related)
|
H00031 | Breast cancer |
P04637
(related)
P38398 (related) |
H00032 | Thyroid cancer |
P04637
(related)
|
H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
H00038 | Malignant melanoma |
P04637
(related)
|
H00039 | Basal cell carcinoma |
P04637
(related)
|
H00040 | Squamous cell carcinoma |
P04637
(related)
|
H00041 | Kaposi's sarcoma |
P04637
(related)
|
H00042 | Glioma |
P04637
(related)
P04637 (marker) |
H00044 | Cancer of the anal canal |
P04637
(related)
|
H00046 | Cholangiocarcinoma |
P04637
(related)
|
H00047 | Gallbladder cancer |
P04637
(related)
|
H00048 | Hepatocellular carcinoma |
P04637
(related)
|
H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
H01007 | Choroid plexus papilloma |
P04637
(related)
|
H00021 | Renal cell carcinoma |
P04637
(marker)
|
H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
H00342 | Tuberculosis |
P11473
(related)
|
H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
H00059 | Huntington's disease (HD) |
P42858
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
MESH or OMIM | name |
KNApSAcK
metabolite |
---|---|---|
D006528 | Carcinoma, Hepatocellular |
C00003749
|
D009202 | Cardiomyopathies |
C00003749
|
D006937 | Hypercholesterolemia |
C00003749
|
D009374 | Neoplasms, Experimental |
C00003749
|
D012878 | Skin Neoplasms |
C00003749
|
D014947 | Wounds and Injuries |
C00003749
|