Paeonia lactiflora
Species
KNApSAcK Entry
| Organism name | Paeonia lactiflora |
|---|---|
| Genus | Paeonia |
| Family | Paeoniaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Paeonia lactiflora |
|---|---|
| Linked NCBI taxonomy ID | 35924 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Paeoniaceae |
|---|---|
| ID | 24943 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | eudicotyledons |
|---|---|
| ID | 71240 |
Natural Activity
List (41)
| Species | Activity |
|---|---|
| Paeonia lactiflora Pall. | Analgesic |
| Paeonia lactiflora Pall. | Antiaggregant |
| Paeonia lactiflora Pall. | Antiaging |
| Paeonia lactiflora Pall. | Antiallergic |
| Paeonia lactiflora Pall. | Antianaphylactic |
| Paeonia lactiflora Pall. | Antiatherogenic |
| Paeonia lactiflora Pall. | Antibacterial |
| Paeonia lactiflora Pall. | Anticholinergic |
| Paeonia lactiflora Pall. | Anticonvulsant |
| Paeonia lactiflora Pall. | Antidiaphoretic |
| Paeonia lactiflora Pall. | Antiedemic |
| Paeonia lactiflora Pall. | Antifatigue |
| Paeonia lactiflora Pall. | Antiherpetic |
| Paeonia lactiflora Pall. | Antiinflammatory |
| Paeonia lactiflora Pall. | Antimutagenic |
| Paeonia lactiflora Pall. | Antioxidant |
| Paeonia lactiflora Pall. | Antipyretic |
| Paeonia lactiflora Pall. | Antiradicular |
| Paeonia lactiflora Pall. | Antiseptic |
| Paeonia lactiflora Pall. | Antispasmodic |
| Paeonia lactiflora Pall. | Antistress |
| Paeonia lactiflora Pall. | Antitestosterone |
| Paeonia lactiflora Pall. | Antitumor |
| Paeonia lactiflora Pall. | Antiulcer |
| Paeonia lactiflora Pall. | Antiviral |
| Paeonia lactiflora Pall. | Astringent |
| Paeonia lactiflora Pall. | Bitter |
| Paeonia lactiflora Pall. | Cardioprotective |
| Paeonia lactiflora Pall. | CNS-Depressant |
| Paeonia lactiflora Pall. | Fibrinolytic |
| Paeonia lactiflora Pall. | Fungicide |
| Paeonia lactiflora Pall. | Hepatoprotective |
| Paeonia lactiflora Pall. | Hypotensive |
| Paeonia lactiflora Pall. | Immunostimulant |
| Paeonia lactiflora Pall. | Memorigenic |
| Paeonia lactiflora Pall. | Myorelaxant |
| Paeonia lactiflora Pall. | Phagocytotic |
| Paeonia lactiflora Pall. | Sedative |
| Paeonia lactiflora Pall. | Tonic |
| Paeonia lactiflora Pall. | Uterocontractant |
| Paeonia lactiflora Pall. | Vasodilator |
Metabolite list (11)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00044995
|
Paeonianin A
|
No. 126 | No. 81 |
|
||||
|
C00044997
|
Paeonianin C
|
No. 126 | No. 81 |
|
||||
|
C00044996
|
Paeonianin B
|
No. 126 | No. 81 |
|
||||
|
C00044998
|
Paeonianin D
|
No. 126 | No. 81 |
|
||||
|
C00044999
|
Paeonianin E
|
No. 226 | No. 81 |
|
||||
|
C00032107
|
Paeonin A
/ (+)-Paeonin A |
CHEMBL1077641
|
No. 1069 |
|
||||
|
C00011060
|
Lactiflorin
|
No. 1566 |
|
|||||
|
C00003011
|
Paeoniflorin
|
CHEMBL1078549
CHEMBL1397567 CHEMBL1972762 |
C015423
|
4 / 4 / 8 | 3 / 2 | No. 1566 |
|
|
|
C00032108
|
Paeonin B
/ (+)-Paeonin B |
CHEMBL1078549
CHEMBL1397567 CHEMBL1972762 |
4 / 4 / 8 | No. 1566 |
|
|||
|
C00048043
|
Paeonin C
/ (+)-Paeonin C |
CHEMBL1078550
|
No. 1566 |
|
||||
|
C00002652
|
beta-Glucogallin
|
CHEMBL480283
|
11 / 2 / 2 | No. 2223 |
|
Human Protein / Gene in interactions
15 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003011 C00032108 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00003011 C00032108 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00003011 C00032108 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003011 C00032108 | 1 / 2 |
| O94806 | Serine/threonine-protein kinase D3 | Pkd | C00002652 | 0 / 0 |
| Q04759 | Protein kinase C theta type | Delta | C00002652 | 0 / 1 |
| Q02156 | Protein kinase C epsilon type | Eta | C00002652 | 0 / 0 |
| Q05513 | Protein kinase C zeta type | Iota | C00002652 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00002652 | 0 / 0 |
| Q05655 | Protein kinase C delta type | Delta | C00002652 | 0 / 0 |
| P05129 | Protein kinase C gamma type | Alpha | C00002652 | 1 / 1 |
| P05771 | Protein kinase C beta type | Alpha | C00002652 | 0 / 0 |
| P24723 | Protein kinase C eta type | Eta | C00002652 | 1 / 0 |
| P41743 | Protein kinase C iota type | Iota | C00002652 | 0 / 0 |
| Q15139 | Serine/threonine-protein kinase D1 | Pkd | C00002652 | 0 / 0 |
3 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 664 | BNIP3, NIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
C00003011
|
| 3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
C00003011
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00003011
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (6)
| OMIM | preferred title | UniProt |
|---|---|---|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #605361 | Spinocerebellar ataxia 14; sca14 |
P05129
|
| #601367 | Stroke, ischemic |
P24723
|
KEGG DISEASE (10)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00063 | Spinocerebellar ataxia (SCA) |
P05129
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00408 | Type I diabetes mellitus |
Q04759
(related)
|