Species

KNApSAcK Entry

Organism name Opuntia dillenii HAW.
Genus Opuntia
Family Cactaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Opuntia
Linked NCBI taxonomy ID 106975
Linked level genus

Family

Family in NCBI taxonomy Cactaceae
ID 3593

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005491 External link 512 Quercetin 3-methyl ether 7-glucoside
/ 3-O-Methylquercetin 7-O-beta-D-glucopyranoside
CHEMBL260805
CHEMBL574682
1 / 0 / 3 No. 2 No. 15
C00002668 External link 512 Protocatechuic acid
/ 3,4-Dihydroxybenzoic acid
CHEMBL37537
C009091
33 / 19 / 19 2 / 0 No. 817 No. 81

Human Protein / Gene in interactions

34 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00002668 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00005491 0 / 3
Q13093 Platelet-activating factor acetylhydrolase Enzyme C00002668 3 / 0
P06746 DNA polymerase beta Enzyme C00002668 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00002668 1 / 1
P43166 Carbonic anhydrase 7 Lyase C00002668 0 / 0
P22894 Neutrophil collagenase M10A C00002668 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00002668 2 / 2
P00918 Carbonic anhydrase 2 Lyase C00002668 1 / 2
P02768 Serum albumin Secreted protein C00002668 0 / 0
Q9GZT9 Egl nine homolog 1 Enzyme C00002668 1 / 1
P23280 Carbonic anhydrase 6 Lyase C00002668 0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00002668 0 / 0
P16581 E-selectin Adhesion C00002668 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00002668 1 / 2
O75496 Geminin Unclassified protein C00002668 0 / 0
P15121 Aldose reductase Enzyme C00002668 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00002668 0 / 0
P07711 Cathepsin L1 C1A C00002668 0 / 0
P03956 Interstitial collagenase M10A C00002668 0 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00002668 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00002668 0 / 1
P08253 72 kDa type IV collagenase M10A C00002668 1 / 3
P03372 Estrogen receptor NR3A1 C00002668 1 / 1
P14151 L-selectin Adhesion C00002668 0 / 0
P16109 P-selectin Adhesion C00002668 1 / 0
Q9UNA4 DNA polymerase iota Enzyme C00002668 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00002668 4 / 3
P08254 Stromelysin-1 M10A C00002668 1 / 0
P22748 Carbonic anhydrase 4 Lyase C00002668 1 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002668 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00002668 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00002668 1 / 4
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002668 0 / 0

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1312 COMT catechol-O-methyltransferase (EC:2.1.1.6) C00002668
2023 ENO1, ENO1L1, MPB1, NNE, PPH enolase 1, (alpha) (EC:4.2.1.11) C00002668

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (19)

OMIM preferred title UniProt
#600807 Asthma, susceptibility to Q13093
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#609820 Erythrocytosis, familial, 3; ecyt3 Q9GZT9
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#232300 Glycogen storage disease ii P10253
#143860 Hyperchlorhidrosis, isolated O43570
#147050 Ige responsiveness, atopic; iger Q13093
#603932 Intervertebral disc disease; idd P14780
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093
#600852 Retinitis pigmentosa 17; rp17 P22748
#601367 Stroke, ischemic P16109
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (21)

KEGG name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00026 Endometrial Cancer P03372 (marker)
H00028 Choriocarcinoma P03956 (related)
P08253 (related)
H00025 Penile cancer P08253 (related)
P14780 (related)
P35354 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H00017 Esophageal cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00236 Congenital polycythemia Q9GZT9 (related)