Species

KNApSAcK Entry

Organism name Streptomyces strain MI689-SF6
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces
Linked NCBI taxonomy ID 1883
Linked level genus

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002669 External link 512 Pyrocatechuic acid
/ o-Pyrocatechuic acid
/ 2,3-Dihydroxybenzoic acid
CHEMBL1432
C009135
12 / 6 / 5 1 / 4 No. 817 No. 81

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00002669 1 / 1
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00002669 0 / 0
P22894 Neutrophil collagenase M10A C00002669 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00002669 2 / 2
P02768 Serum albumin Secreted protein C00002669 0 / 0
P16581 E-selectin Adhesion C00002669 0 / 0
P03956 Interstitial collagenase M10A C00002669 0 / 1
P08253 72 kDa type IV collagenase M10A C00002669 1 / 3
P14151 L-selectin Adhesion C00002669 0 / 0
P16109 P-selectin Adhesion C00002669 1 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00002669 0 / 0
P08254 Stromelysin-1 M10A C00002669 1 / 0

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
4313 MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) C00002669

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#603932 Intervertebral disc disease; idd P14780
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601367 Stroke, ischemic P16109

KEGG DISEASE (5)

KEGG name UniProt
H00028 Choriocarcinoma P03956 (related)
P08253 (related)
H00025 Penile cancer P08253 (related)
P14780 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)

Diseases related to CTD interactions

4 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D058186 Acute Kidney Injury C00002669
D034381 Hearing Loss C00002669
D007674 Kidney Diseases C00002669
D015837 Vestibular Diseases C00002669