Species

KNApSAcK Entry

Organism name Curculigo orchioides
Genus Curculigo
Family Hypoxidaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Curculigo orchioides
Linked NCBI taxonomy ID 681286
Linked level species

Family

Family in NCBI taxonomy Hypoxidaceae
ID 4674

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Natural Activity

List (15)

Species Activity
Curculigo orchioides Gaertn. Alterative
Curculigo orchioides Gaertn. Analgesic
Curculigo orchioides Gaertn. Antpyretic
Curculigo orchioides Gaertn. Aperitif
Curculigo orchioides Gaertn. Aphrodisiac
Curculigo orchioides Gaertn. Bitter
Curculigo orchioides Gaertn. Carminative
Curculigo orchioides Gaertn. Demulcent
Curculigo orchioides Gaertn. Depurative
Curculigo orchioides Gaertn. Diuretic
Curculigo orchioides Gaertn. Lipogenic
Curculigo orchioides Gaertn. Litholytic
Curculigo orchioides Gaertn. Nervine
Curculigo orchioides Gaertn. Pectoral
Curculigo orchioides Gaertn. Tonic

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00032097 External link 512 Orcinol glucoside
/ Orcinol-3-O-beta-D-glycopyranoside
/ (-)-Orcinol-3-O-beta-D-glycopyranoside
CHEMBL1387960
4 / 8 / 3 No. 45 No. 72
C00031704 External link 512 Curculigoside C
/ (-)-Curculigoside C
No. 122 No. 15
C00031703 External link 512 Curculigoside B
CHEMBL403237
C077853
No. 122 No. 15
C00035360 External link 512 Orchioside A
/ (-)-Orchioside A
CHEMBL258047
No. 122 No. 15
C00002674 External link 512 Syringic acid
/ 4-Hydroxy-3,5-dimethoxybenzoic acid
CHEMBL1414
C001945
12 / 3 / 5 No. 1073
C00035361 External link 512 Orchioside B
/ (+)-Orchioside B
No. 4297

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P06746 DNA polymerase beta Enzyme C00032097 0 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00002674 0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00002674 0 / 0
P43166 Carbonic anhydrase 7 Lyase C00002674 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00002674 1 / 2
P23280 Carbonic anhydrase 6 Lyase C00002674 0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00002674 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00002674 1 / 2
P15121 Aldose reductase Enzyme C00002674 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00002674 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00032097 7 / 3
Q16790 Carbonic anhydrase 9 Lyase C00002674 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00032097 0 / 0
P07451 Carbonic anhydrase 3 Lyase C00002674 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00002674 1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00032097 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#137800 Glioma susceptibility 1; glm1 O75874
#143860 Hyperchlorhidrosis, isolated O43570
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#600852 Retinitis pigmentosa 17; rp17 P22748

KEGG DISEASE (8)

KEGG name UniProt
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)