Senecio chionophilus

• Index
• Plant Species
• Metabolite list (12)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Senecio chionophilus
Genus	Senecio
Family	Asteraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Senecio
Linked NCBI taxonomy ID	18794
Linked level	genus

Family

Family in NCBI taxonomy	Asteraceae
ID	4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (12)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00045098	Taraxasterone / (+)-Taraxasterone
C00044566	beta-Amyrenone	CHEMBL461060				No. 13	No. 51
C00003737	alpha-Amyrin / alpha-Amyrine / alpha-Amyrenol					No. 23	No. 51
C00003738	beta-Amyrin / beta-Amirin / beta-Amyrine / beta-Amyrenol		C036380		0 / 4	No. 23	No. 51
C00003749	Lupeol / Lupenol / (+)-Lupenol	CHEMBL289191 CHEMBL459702	C010480	3 / 0 / 0	2 / 6	No. 23	No. 51
C00019220	Lupenone	CHEMBL486393 CHEMBL575188		3 / 4 / 2		No. 23	No. 51
C00003757	Taraxasterol	CHEMBL497525	C079988			No. 23	No. 51
C00003672	Sitosterol / beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol	CHEMBL221542 CHEMBL1398443 CHEMBL1875388		17 / 19 / 12		No. 53	No. 11
C00012483	Betula pubescens / Caryophyllene oxide / trans-Caryophyllene oxide / beta-Caryophyllene epoxide / (-)-Epoxydihydrocaryophyllene / 6,7-Epoxy-3(15)-caryophyllene / (-)-beta-Caryophyllene epoxide / 4beta,5alpha-Epoxycaryophyllene / Caryophyllene 4beta,5alpha-epoxide	CHEMBL399036 CHEMBL508894 CHEMBL479134 CHEMBL1513806 CHEMBL1553274		3 / 1 / 3		No. 500
C00019308	Doursterol / Daucosterin / 3-O-beta-D-Glucopyranosyl sitosterol / beta-Sitosterol 3-O-beta-D-glucopyranoside	CHEMBL197711 CHEMBL506678 CHEMBL2304043	C011015	5 / 4 / 2	0 / 3	No. 520
C00017413	6beta-Angeloyloxy-10alphaH-9-oxofuranoeremophilane					No. 645
C00002698	Piceol / p-Hydroxyacetophenone / 4'-Hydroxyacetophenone	CHEMBL201083	C031335	5 / 3 / 3		No. 2849

Human Protein / Gene in interactions

26 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P08047	Transcription factor Sp1	Unclassified protein	C00003672 C00003749 C00019308	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00003672 C00012483	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00003672 C00012483	0 / 1
P06746	DNA polymerase beta	Enzyme	C00003672 C00019308	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00003672 C00019308	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00003672 C00019308	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00003672 C00019220	4 / 2
P00734	Prothrombin	S1A	C00003672 C00019308	4 / 2
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00003672 C00012483	0 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00003672	1 / 0
P11387	DNA topoisomerase 1	Isomerase	C00003749	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003749	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00002698	0 / 0
P08183	Multidrug resistance protein 1	drug	C00003672	1 / 0
P51649	Succinate-semialdehyde dehydrogenase, mitochondrial	Oxidoreductase	C00002698	1 / 1
P16473	Thyrotropin receptor	Glycohormone receptor	C00003672	3 / 2
P80404	4-aminobutyrate aminotransferase, mitochondrial	Transferase	C00002698	1 / 1
Q96RI1	Bile acid receptor	NR1H4	C00019220	0 / 0
P37058	Testosterone 17-beta-dehydrogenase 3	Enzyme	C00002698	1 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00003672	0 / 0
P03372	Estrogen receptor	NR3A1	C00003672	1 / 1
Q8TDU6	G-protein coupled bile acid receptor 1	Steroid-like ligand receptor	C00019220	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00003672	2 / 0
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00002698	0 / 0
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00003672	1 / 1
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00003672	1 / 1

2 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00003749
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00003749

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions