Illicium anisatum
Species
KNApSAcK Entry
| Organism name | Illicium anisatum |
|---|---|
| Genus | Illicium |
| Family | Illiciaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Illicium anisatum |
|---|---|
| Linked NCBI taxonomy ID | 124794 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Schisandraceae |
|---|---|
| ID | 16733 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Magnoliophyta |
|---|---|
| ID | 3398 |
Metabolite list (11)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00009074
|
Procyanidin B7
/ Catechin-(4beta->6)-catechin |
CHEMBL506487
CHEMBL502984 CHEMBL451115 |
No. 16 | No. 19 |
|
|||
|
C00009277
|
Proanthocyanidin A1
|
CHEMBL286933
CHEMBL81646 CHEMBL450916 |
13 / 3 / 4 | No. 16 | No. 19 |
|
||
|
C00009086
|
Epicatechin-(4beta->6)-epicatechin-(4beta->8)-catechin
|
CHEMBL592228
|
2 / 3 / 4 | No. 29 | No. 19 |
|
||
|
C00009097
|
Arecatamnin A1
/ [Epicatechin-(4beta->8)]2-catechin |
CHEMBL290632
|
13 / 5 / 6 | No. 29 | No. 19 |
|
||
|
C00009093
|
Catechin-(4alpha->8)-epicatechin-(4beta->8)-catechin
|
CHEMBL290632
|
13 / 5 / 6 | No. 29 | No. 19 |
|
||
|
C00009089
|
Arecatannin B1
|
CHEMBL592329
|
2 / 3 / 4 | No. 29 | No. 19 |
|
||
|
C00003212
|
Anisatin
|
CHEMBL220362
CHEMBL517697 |
1 / 2 / 2 | No. 680 | No. 38 |
|
||
|
C00008909
|
6-Prenylcatechin
|
No. 2306 |
|
|||||
|
C00008910
|
8-Prenylcatechin
|
No. 2306 |
|
|||||
|
C00021774
|
Pseudoanisatin
|
CHEMBL504536
CHEMBL1473307 |
1 / 0 / 1 | No. 2408 |
|
|||
|
C00002713
|
Anethole
|
CHEMBL452630
CHEMBL1468832 |
C006578
|
6 / 21 / 49 | 16 / 13 | No. 2748 | No. 6 |
|
Human Protein / Gene in interactions
21 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P14780 | Matrix metalloproteinase-9 | M10A | C00003212 C00009086 C00009089 C00009093 C00009097 | 2 / 2 |
| P08253 | 72 kDa type IV collagenase | M10A | C00009086 C00009089 C00009093 C00009097 | 1 / 3 |
| Q05655 | Protein kinase C delta type | Delta | C00009093 C00009097 C00009277 | 0 / 0 |
| P24723 | Protein kinase C eta type | Eta | C00009093 C00009097 C00009277 | 1 / 0 |
| P05771 | Protein kinase C beta type | Alpha | C00009093 C00009097 C00009277 | 0 / 0 |
| P05129 | Protein kinase C gamma type | Alpha | C00009093 C00009097 C00009277 | 1 / 1 |
| P41743 | Protein kinase C iota type | Iota | C00009093 C00009097 C00009277 | 0 / 0 |
| Q15139 | Serine/threonine-protein kinase D1 | Pkd | C00009093 C00009097 C00009277 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00009093 C00009097 C00009277 | 0 / 0 |
| O94806 | Serine/threonine-protein kinase D3 | Pkd | C00009093 C00009097 C00009277 | 0 / 0 |
| Q02156 | Protein kinase C epsilon type | Eta | C00009093 C00009097 C00009277 | 0 / 0 |
| Q04759 | Protein kinase C theta type | Delta | C00009093 C00009097 C00009277 | 0 / 1 |
| Q05513 | Protein kinase C zeta type | Iota | C00009093 C00009097 C00009277 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002713 C00021774 | 0 / 1 |
| P49763 | Placenta growth factor | Unclassified protein | C00009277 | 0 / 0 |
| P15692 | Vascular endothelial growth factor A | Secreted protein | C00009277 | 1 / 2 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002713 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002713 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00002713 | 3 / 2 |
| P02545 | Prelamin-A/C | Unclassified protein | C00002713 | 11 / 10 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00002713 | 7 / 37 |
16 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00002713
|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00002713
|
| 3551 | IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) |
C00002713
|
| 5604 | MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1 | mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) |
C00002713
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00002713
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00002713
|
| 5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) |
C00002713
|
| 4313 | MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) |
C00002713
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00002713
|
| 4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00002713
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00002713
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00002713
|
| 5328 | PLAU, ATF, BDPLT5, QPD, UPA, URK, u-PA | plasminogen activator, urokinase (EC:3.4.21.73) |
C00002713
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002713
|
| 7076 | TIMP1, CLGI, EPA, EPO, HCI, TIMP | TIMP metallopeptidase inhibitor 1 |
C00002713
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00002713
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (27)
| OMIM | preferred title | UniProt |
|---|---|---|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P04637
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #211980 | Lung cancer |
P04637
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #603933 | Microvascular complications of diabetes, susceptibility to, 1; mvcd1 |
P15692
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #605361 | Spinocerebellar ataxia 14; sca14 |
P05129
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601367 | Stroke, ischemic |
P24723
|
KEGG DISEASE (53)
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
P15692 (related) |
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P08253 (related) P14780 (related) |
| H00026 | Endometrial Cancer |
P04637
(related)
|
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00028 | Choriocarcinoma |
P04637
(related)
P08253 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00033 | Adrenal carcinoma |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
P15692 (marker) |
| H00063 | Spinocerebellar ataxia (SCA) |
P05129
(related)
|
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00408 | Type I diabetes mellitus |
Q04759
(related)
|
Diseases related to CTD interactions
13 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D001919 | Bradycardia |
C00002713
|
| D002286 | Carcinoma, Ehrlich Tumor |
C00002713
|
| D003877 | Dermatitis, Contact |
C00002713
|
| D056486 | Drug-Induced Liver Injury |
C00002713
|
| D005767 | Gastrointestinal Diseases |
C00002713
|
| D007022 | Hypotension |
C00002713
|
| D007249 | Inflammation |
C00002713
|
| D008107 | Liver Diseases |
C00002713
|
| D008113 | Liver Neoplasms |
C00002713
|
| D009362 | Neoplasm Metastasis |
C00002713
|
| D010243 | Paralysis |
C00002713
|
| D013276 | Stomach Ulcer |
C00002713
|
| D013927 | Thrombosis |
C00002713
|