Species

KNApSAcK Entry

Organism name Anethum graveolens
Genus Anethum
Family Apiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Anethum graveolens
Linked NCBI taxonomy ID 40922
Linked level species

Family

Family in NCBI taxonomy Apiaceae
ID 4037

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Natural Activity

List (25)

Species Activity
Anethum graveolens L. Antibacterial
Anethum graveolens L. Antiseptic
Anethum graveolens L. Antispasmodic
Anethum graveolens L. Antitumor
Anethum graveolens L. Aperitif
Anethum graveolens L. Cardiodepressant
Anethum graveolens L. Carminative
Anethum graveolens L. Detergent
Anethum graveolens L. Digestive
Anethum graveolens L. Diuretic
Anethum graveolens L. Fungicide
Anethum graveolens L. Hypoglycemic
Anethum graveolens L. Hypotensive
Anethum graveolens L. Insectifuge
Anethum graveolens L. Lactagogue
Anethum graveolens L. Laxative
Anethum graveolens L. Myorelaxant
Anethum graveolens L. Narcotic
Anethum graveolens L. Psychedelic
Anethum graveolens L. Respirastimulant
Anethum graveolens L. Sedative
Anethum graveolens L. Soporific
Anethum graveolens L. Stimulant
Anethum graveolens L. Stomachic
Anethum graveolens L. Vasodilator

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005527 External link 512 Isorhamnetin 3-glucuronide
No. 2 No. 15
C00005141 External link 512 Kaempferol 3-glucuronide
/ Kaempferol-3-O-beta-D-glucuronide
No. 2 No. 15
C00010868 External link 512 D-Limonene
/ (+)-S-Carvone
/ d-(+)-Limonene
CHEMBL15799
CHEMBL449062
7 / 21 / 48 No. 848 No. 35
C00010891 External link 512 (S)-(+)-Carvone
CHEMBL15676
CHEMBL501949
8 / 9 / 9 No. 1740 No. 35
C00002737 External link 512 Dillapiole
CHEMBL470874
C059115
1 / 0 / 0 No. 1917 No. 6

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10828 Thyroid hormone receptor beta NR1A2 C00010868 C00010891 3 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00010868 C00010891 0 / 0
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00010868 0 / 0
P06746 DNA polymerase beta Enzyme C00002737 0 / 0
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00010868 0 / 0
P02545 Prelamin-A/C Unclassified protein C00010868 11 / 10
P04637 Cellular tumor antigen p53 Transcription Factor C00010868 7 / 37
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00010868 0 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00010891 0 / 0
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00010891 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00010891 2 / 0
O00255 Menin Unclassified protein C00010891 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00010891 1 / 2
Q13148 TAR DNA-binding protein 43 Unclassified protein C00010891 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (27)

OMIM preferred title UniProt
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#133239 Esophageal cancer P04637
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#145000 Hyperparathyroidism 1; hrpt1 O00255
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#211980 Lung cancer P04637
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#260500 Papilloma of choroid plexus; cpp P04637
#275210 Restrictive dermopathy, lethal P02545
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (55)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
H00036 Osteosarcoma P04637 (related)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
P35354 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)