Flindersia bennettiana
Species
KNApSAcK Entry
| Organism name | Flindersia bennettiana |
|---|---|
| Genus | Flindersia |
| Family | Rutaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Flindersia bennettiana |
|---|---|
| Linked NCBI taxonomy ID | 67923 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Rutaceae |
|---|---|
| ID | 23513 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (3)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00002488
|
Osthol
/ Osthole |
CHEMBL52229
|
C046627
|
12 / 6 / 5 | 7 / 4 | No. 466 | No. 25 |
|
|
C00000583
|
Isopimpinellin
|
CHEMBL140796
|
C015304
|
9 / 3 / 4 | 2 / 0 | No. 606 | No. 25 |
|
|
C00000300
|
Seselin
/ Amyrolin / Seseline |
CHEMBL71358
|
2 / 0 / 0 | No. 750 | No. 25 |
|
Human Protein / Gene in interactions
19 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P56817 | Beta-secretase 1 | A1A | C00000300 C00000583 C00002488 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000583 C00002488 | 0 / 1 |
| P04406 | Glyceraldehyde-3-phosphate dehydrogenase | Enzyme | C00000300 C00002488 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00002488 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00002488 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002488 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00000583 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00002488 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00002488 | 0 / 0 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00002488 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00002488 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00002488 | 6 / 4 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000583 | 2 / 2 |
| P06746 | DNA polymerase beta | Enzyme | C00000583 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000583 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000583 | 0 / 0 |
| O14980 | Exportin-1 | Unclassified protein | C00002488 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000583 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00000583 | 1 / 1 |
9 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00000583
|
| 8856 | NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR | nuclear receptor subfamily 1, group I, member 2 |
C00000583
|
| 2180 | ACSL1, ACS1, FACL1, FACL2, LACS, LACS1, LACS2 | acyl-CoA synthetase long-chain family member 1 (EC:6.2.1.3) |
C00002488
|
| 1374 | CPT1A, CPT1, CPT1-L, L-CPT1 | carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21) |
C00002488
|
| 4313 | MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) |
C00002488
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00002488
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00002488
|
| 5465 | PPARA, NR1C1, PPAR, PPARalpha, hPPAR | peroxisome proliferator-activated receptor alpha |
C00002488
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002488
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (9)
| OMIM | preferred title | UniProt |
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
KEGG DISEASE (8)
| KEGG | name | UniProt |
|---|---|---|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|