Species

KNApSAcK Entry

Organism name Parameria laevigata MOLDENKE
Genus Parameria
Family Apocynaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Parameria
Linked NCBI taxonomy ID 429499
Linked level genus

Family

Family in NCBI taxonomy Apocynaceae
ID 4056

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002934 External link 512 Proanthocyanidin A2
/ Proanthocyanidin A-2
/ (+)-Proanthocyanidin A-2
CHEMBL286933
CHEMBL81646
CHEMBL450916
C473740
13 / 3 / 4 No. 16 No. 19
C00009276 External link 512 Proanthocyanidin A6
No. 16 No. 19
C00009291 External link 512 Cinnamtannin B1
CHEMBL540956
CHEMBL81478
CHEMBL445468
CHEMBL1213875
CHEMBL1213876
14 / 4 / 7 No. 29 No. 19
C00009293 External link 512 Aesculitannin B
CHEMBL540956
CHEMBL81478
CHEMBL445468
CHEMBL1213875
CHEMBL1213876
14 / 4 / 7 No. 29 No. 19
C00013285 External link 512 Parameritannin A1
/ (2R,3R,4S,8S,14R,15R)-2,8-bis(3,4-Dihydroxyphenyl)-6-[(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-4-yl]-4-[(2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-8-yl]-3,4-dihydro-8,14-methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol
CHEMBL1213878
CHEMBL1823107
1 / 0 / 3 No. 113 No. 19
C00033288 External link 512 Parameritannin A2
No. 113 No. 19

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00009291 C00009293 C00013285 0 / 3
Q15139 Serine/threonine-protein kinase D1 Pkd C00002934 C00009291 C00009293 0 / 0
P41743 Protein kinase C iota type Iota C00002934 C00009291 C00009293 0 / 0
P24723 Protein kinase C eta type Eta C00002934 C00009291 C00009293 1 / 0
P05771 Protein kinase C beta type Alpha C00002934 C00009291 C00009293 0 / 0
Q05513 Protein kinase C zeta type Iota C00002934 C00009291 C00009293 0 / 0
Q04759 Protein kinase C theta type Delta C00002934 C00009291 C00009293 0 / 1
Q02156 Protein kinase C epsilon type Eta C00002934 C00009291 C00009293 0 / 0
P05129 Protein kinase C gamma type Alpha C00002934 C00009291 C00009293 1 / 1
P17252 Protein kinase C alpha type Alpha C00002934 C00009291 C00009293 0 / 0
Q05655 Protein kinase C delta type Delta C00002934 C00009291 C00009293 0 / 0
O94806 Serine/threonine-protein kinase D3 Pkd C00002934 C00009291 C00009293 0 / 0
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00009291 C00009293 0 / 0
Q06187 Tyrosine-protein kinase BTK Tec C00009291 C00009293 2 / 2
P15692 Vascular endothelial growth factor A Secreted protein C00002934 1 / 2
P49763 Placenta growth factor Unclassified protein C00002934 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#300755 Agammaglobulinemia, x-linked; xla Q06187
#307200 Isolated growth hormone deficiency, type iii; ighd3 Q06187
#603933 Microvascular complications of diabetes, susceptibility to, 1; mvcd1 P15692
#605361 Spinocerebellar ataxia 14; sca14 P05129
#601367 Stroke, ischemic P24723

KEGG DISEASE (9)

KEGG name UniProt
H00063 Spinocerebellar ataxia (SCA) P05129 (related)
H00018 Gastric cancer P15692 (related)
H00021 Renal cell carcinoma P15692 (marker)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00408 Type I diabetes mellitus Q04759 (related)
H00085 Agammaglobulinemias Q06187 (related)
H00254 Pituitary Dwarfism (PD) Q06187 (related)