Species

KNApSAcK Entry

Organism name Cratoxylum cochinchinense (Lour.) Blume
Genus Cratoxylum
Family Hypericaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Cratoxylum cochinchinense
Linked NCBI taxonomy ID 271749
Linked level species

Family

Family in NCBI taxonomy Hypericaceae
ID 629714

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00034819 External link 512 Cochinchinone B
CHEMBL1173563
No. 14 No. 15
C00030356 External link 512 Garcinone B
CHEMBL560332
No. 18 No. 15
C00002961 External link 512 Macluraxanthone
/ 3-Hydroxyblancoxanthone
CHEMBL478960
5 / 11 / 11 No. 18 No. 15
C00030358 External link 512 Garcinone D
CHEMBL462879
3 / 2 / 2 No. 47 No. 15
C00034820 External link 512 Cochinchinone D
No. 2057

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein C00002961 4 / 1
Q04206 Transcription factor p65 Transcription Factor C00030358 0 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00030358 2 / 2
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00030358 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00002961 4 / 3
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002961 0 / 0
O00255 Menin Unclassified protein C00002961 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00002961 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (13)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P11511 (related)
H00794 Aromatase excess syndrome P11511 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)