Organism name | Hypericum aucheri |
---|---|
Genus | Hypericum |
Family | Hypericaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Hypericum aucheri |
---|---|
Linked NCBI taxonomy ID | 1321321 |
Linked level | species |
Family in NCBI taxonomy | Hypericaceae |
---|---|
ID | 629714 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | rosids |
---|---|
ID | 71275 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00006431
![]() |
3,8''-Biapigenin
|
CHEMBL515252
|
21 / 16 / 12 | No. 34 | No. 18 |
![]() |
||
C00002968
![]() |
Norathyriol
/ 1,3,6,7-Tetrahydroxyxanthoene |
CHEMBL187265
|
C069053
|
9 / 10 / 7 | 4 / 0 | No. 71 | No. 15 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00006431 | 0 / 0 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00006431 | 0 / 0 |
P14618 | Pyruvate kinase PKM | Enzyme | C00006431 | 0 / 0 |
P06746 | DNA polymerase beta | Enzyme | C00006431 | 0 / 0 |
P04062 | Glucosylceramidase | Enzyme | C00006431 | 6 / 4 |
P39900 | Macrophage metalloelastase | M10A | C00002968 | 0 / 0 |
P14780 | Matrix metalloproteinase-9 | M10A | C00002968 | 2 / 2 |
Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00006431 | 0 / 0 |
P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00002968 | 1 / 1 |
P49327 | Fatty acid synthase | Transferase | C00002968 | 0 / 0 |
P54132 | Bloom syndrome protein | Enzyme | C00006431 | 1 / 2 |
P39748 | Flap endonuclease 1 | Enzyme | C00006431 | 0 / 0 |
O75496 | Geminin | Unclassified protein | C00006431 | 0 / 0 |
P03956 | Interstitial collagenase | M10A | C00002968 | 0 / 1 |
Q9Y253 | DNA polymerase eta | Enzyme | C00006431 | 1 / 1 |
P45452 | Collagenase 3 | M10A | C00002968 | 1 / 1 |
P08253 | 72 kDa type IV collagenase | M10A | C00002968 | 1 / 3 |
P12821 | Angiotensin-converting enzyme | M2 | C00002968 | 4 / 2 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00006431 | 0 / 1 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00006431 | 0 / 0 |
O75164 | Lysine-specific demethylase 4A | Enzyme | C00006431 | 0 / 0 |
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00006431 | 0 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00006431 | 4 / 3 |
P08254 | Stromelysin-1 | M10A | C00002968 | 1 / 0 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00006431 | 0 / 0 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00006431 | 0 / 0 |
P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00006431 | 0 / 0 |
P63165 | Small ubiquitin-related modifier 1 | Unclassified protein | C00006431 | 1 / 1 |
Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00006431 | 2 / 1 |
Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00006431 | 1 / 1 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00002968
|
5465 | PPARA, NR1C1, PPAR, PPARalpha, hPPAR | peroxisome proliferator-activated receptor alpha |
C00002968
|
5467 | PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB | peroxisome proliferator-activated receptor delta |
C00002968
|
5468 | PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma | peroxisome proliferator-activated receptor gamma |
C00002968
|
OMIM | preferred title | UniProt |
---|---|---|
#612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
#210900 | Bloom syndrome; blm |
P54132
|
#300615 | Brunner syndrome |
P21397
|
#114500 | Colorectal cancer; crc |
Q14191
|
#614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#608013 | Gaucher disease, perinatal lethal |
P04062
|
#230800 | Gaucher disease, type i |
P04062
|
#230900 | Gaucher disease, type ii |
P04062
|
#231000 | Gaucher disease, type iii |
P04062
|
#231005 | Gaucher disease, type iiic |
P04062
|
#614519 | Hemorrhage, intracerebral, susceptibility to; ich |
P12821
|
#603932 | Intervertebral disc disease; idd |
P14780
|
#613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
#612624 | Microvascular complications of diabetes, susceptibility to, 3; mvcd3 |
P12821
|
#259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
#613705 | Orofacial cleft 10; ofc10 |
P63165
|
#168600 | Parkinson disease, late-onset; pd |
P04062
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#267430 | Renal tubular dysgenesis; rtd |
P12821
|
#602111 | Spondyloepimetaphyseal dysplasia, missouri type |
P45452
|
#601367 | Stroke, ischemic |
P12821
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#277700 | Werner syndrome; wrn |
Q14191
|
#278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG | name | UniProt |
---|---|---|
H00028 | Choriocarcinoma |
P03956
(related)
P08253 (related) |
H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
H00126 | Gaucher disease |
P04062
(related)
|
H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
H00025 | Penile cancer |
P08253
(related)
P14780 (related) |
H00472 | Torg-Winchester syndrome |
P08253
(related)
|
H00036 | Osteosarcoma |
P08684
(marker)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00083 | Allograft rejection |
P12821
(related)
|
H00575 | Renal tubular dysgenesis |
P12821
(related)
|
H00479 | Metaphyseal dysplasias |
P14780
(related)
P45452 (related) |
H00548 | Brunner syndrome |
P21397
(related)
|
H00094 | DNA repair defects |
P54132
(related)
|
H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
H00516 | Isolated orofacial clefts |
P63165
(related)
|
H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|