Garcinia cambogia
Species
KNApSAcK Entry
| Organism name | Garcinia cambogia |
|---|---|
| Genus | Garcinia |
| Family | Clusiaceae / Clusiaceae-Guttiferae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Garcinia |
|---|---|
| Linked NCBI taxonomy ID | 58227 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Clusiaceae |
|---|---|
| ID | 55961 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Natural Activity
List (8)
| Species | Activity |
|---|---|
| Garcinia cambogia (Gaertn.) Desr. | Anorectic |
| Garcinia cambogia (Gaertn.) Desr. | Antilipolytic |
| Garcinia cambogia (Gaertn.) Desr. | Antiobesity |
| Garcinia cambogia (Gaertn.) Desr. | Antiseptic |
| Garcinia cambogia (Gaertn.) Desr. | ATP-Citrate-Lyase Inhibitor |
| Garcinia cambogia (Gaertn.) Desr. | Hypocholesterolemic |
| Garcinia cambogia (Gaertn.) Desr. | Hypotryglyceridemic |
| Garcinia cambogia (Gaertn.) Desr. | Laxative |
Metabolite list (3)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00034889
|
Rheediaxanthone A
|
No. 18 | No. 15 |
|
||||
|
C00031902
|
Cambogin
/ Isogarcinol |
CHEMBL458934
CHEMBL1077027 CHEMBL1098255 CHEMBL2087611 |
2 / 1 / 1 | No. 123 |
|
|||
|
C00002991
|
Garcinol
|
CHEMBL454261
CHEMBL502489 CHEMBL2087609 |
C054597
|
2 / 1 / 1 | 17 / 0 | No. 123 |
|
Human Protein / Gene in interactions
2 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q09472 | Histone acetyltransferase p300 | Enzyme | C00002991 C00031902 | 1 / 1 |
| Q92831 | Histone acetyltransferase KAT2B | Enzyme | C00002991 C00031902 | 0 / 0 |
17 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00002991
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00002991
|
| 637 | BID, FP497 | BH3 interacting domain death agonist |
C00002991
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00002991
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00002991
|
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00002991
|
| 2033 | EP300, KAT3B, RSTS2, p300 | E1A binding protein p300 (EC:2.3.1.48) |
C00002991
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00002991
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00002991
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00002991
|
| 4316 | MMP7, MMP-7, MPSL1, PUMP-1 | matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23) |
C00002991
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00002991
|
| 5295 | PIK3R1, AGM7, GRB1, p85, p85-ALPHA | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
C00002991
|
| 5747 | PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK | protein tyrosine kinase 2 (EC:2.7.10.2) |
C00002991
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002991
|
| 6714 | SRC, ASV, SRC1, c-SRC, p60-Src | v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (EC:2.7.10.2) |
C00002991
|
| 7412 | VCAM1, CD106, INCAM-100 | vascular cell adhesion molecule 1 |
C00002991
|