Species

KNApSAcK Entry

Organism name Anabaena flos-aquae
Genus Anabaena
Family Euphorbiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Dolichospermum flos-aquae
Linked NCBI taxonomy ID 1166
Linked level species

Family

Family in NCBI taxonomy Nostocaceae
ID 1162

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00007247 External link 512 Linolenic acid
/ alpha-Linolenic acid
/ (Z,Z,Z)-Octadeca-9,12,15-trienoic acid
D017962
22 / 5
C00000922 External link 512 Canthaxanthin
/ beta-Carotene-4,4'-dione
CHEMBL1329004
D016644
4 / 4 / 3 0 / 1 No. 26 No. 59
C00000925 External link 512 Myxoxanthine
/ beta-Echinenone
C105515
No. 26 No. 59
C00000386 External link 512 9R-Hydroxy-10E,12Z,15Z-Octadecatrienoic acid
No. 300 No. 68
C00002273 External link 512 Anatoxin alpha
CHEMBL25619
CHEMBL2332144
C509790
5 / 4 / 1 No. 5263 No. 1

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P49798 Regulator of G-protein signaling 4 Unclassified protein C00002273 2 / 0
P17787 Neuronal acetylcholine receptor subunit beta-2 CHRN beta C00002273 1 / 1
P43681 Neuronal acetylcholine receptor subunit alpha-4 CHRN alpha C00002273 1 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00002273 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00000922 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00000922 0 / 0
P36544 Neuronal acetylcholine receptor subunit alpha-7 CHRN alpha C00002273 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00000922 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00000922 4 / 3

22 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
8647 ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP ATP-binding cassette, sub-family B (MDR/TAP), member 11 C00007247
1374 CPT1A, CPT1, CPT1-L, L-CPT1 carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21) C00007247
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00007247
1591 CYP24A1, CP24, CYP24, HCAI, P450-CC24 cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) C00007247
1557 CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19 cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00007247
1559 CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00007247
1571 CYP2E1, CPE1, CYP2E, P450-J, P450C2E cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) C00007247
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00007247
3992 FADS1, D5D, FADS6, FADSD5, LLCDL1, TU12 fatty acid desaturase 1 (EC:1.14.19.-) C00007247
2729 GCLC, GCL, GCS, GLCL, GLCLC glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) C00007247
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00007247
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00007247
3565 IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 interleukin 4 C00007247
3827 KNG1, BDK, BK, KNG kininogen 1 C00007247
9971 NR1H4, BAR, FXR, HRR-1, HRR1, RIP14 nuclear receptor subfamily 1, group H, member 4 C00007247
5465 PPARA, NR1C1, PPAR, PPARalpha, hPPAR peroxisome proliferator-activated receptor alpha C00007247
100136658 C00007247
5467 PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB peroxisome proliferator-activated receptor delta C00007247
5468 PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma peroxisome proliferator-activated receptor gamma C00007247
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00007247
6256 RXRA, NR2B1 retinoid X receptor, alpha C00007247
7421 VDR, NR1I1 vitamin D (1,25- dihydroxyvitamin D3) receptor C00007247

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#600513 Epilepsy, nocturnal frontal lobe, 1; enfl1 P43681
#605375 Epilepsy, nocturnal frontal lobe, 3; enfl3 P17787
#600274 Frontotemporal dementia; ftd P10636
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (4)

KEGG name UniProt
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00807 Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) P17787 (related)
P43681 (related)

Diseases related to CTD interactions

6 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D005128 Eye Diseases C00000922
D001930 Brain Injuries C00007247
D003866 Depressive Disorder C00007247
D064420 Drug-Related Side Effects and Adverse Reactions C00007247
D007249 Inflammation C00007247
D009422 Nervous System Diseases C00007247