Cosmos pringlei
Species
KNApSAcK Entry
| Organism name | Cosmos pringlei |
|---|---|
| Genus | Cosmos |
| Family | Asteraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Cosmos |
|---|---|
| Linked NCBI taxonomy ID | 41555 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Asteraceae |
|---|---|
| ID | 4210 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (9)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003240
|
Costunolide
|
CHEMBL86416
CHEMBL190377 CHEMBL1575037 |
C002602
|
10 / 7 / 15 | 0 / 3 | No. 107 | No. 38 |
|
|
C00045462
|
Zaluzanin C isobutyrate
/ (+)-Zaluzanin C isobutyrate |
No. 206 | No. 38 |
|
||||
|
C00045463
|
Zaluzanin C isovalerate
/ (+)-Zaluzanin C isovalerate |
No. 206 | No. 38 |
|
||||
|
C00045156
|
15-Isovaleroyloxycostunolide
|
No. 249 | No. 38 |
|
||||
|
C00003245
|
Dehydrocostus lactone
|
CHEMBL88985
CHEMBL487201 CHEMBL1939730 |
C083030
|
1 / 1 / 1 | No. 306 | No. 38 |
|
|
|
C00045352
|
Mokko lactone
|
CHEMBL453274
|
No. 363 |
|
||||
|
C00045179
|
3beta-Hydroxy-5alpha-pregn-16-en-20-one
/ (+)-3beta-Hydroxy-5alpha-pregn-16-en-20-one |
C028107
|
No. 1223 |
|
||||
|
C00045150
|
1',2'-Epoxy-3',4'-di-isobutyryl-Z-coniferyl alcohol
|
No. 4559 |
|
|||||
|
C00045164
|
1'-Isovaleroyloxy-4-O-isobutyryleugenol
/ (-)-1'-Isovaleroyloxy-4-O-isobutyryleugenol |
No. 4559 |
|
Human Protein / Gene in interactions
10 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P03372 | Estrogen receptor | NR3A1 | C00003240 C00003245 | 1 / 1 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00003240 | 1 / 1 |
| Q04206 | Transcription factor p65 | Transcription Factor | C00003240 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00003240 | 0 / 3 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00003240 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00003240 | 2 / 3 |
| O00255 | Menin | Unclassified protein | C00003240 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003240 | 1 / 2 |
| Q00653 | Nuclear factor NF-kappa-B p100 subunit | Transcription Factor | C00003240 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00003240 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (7)
| OMIM | preferred title | UniProt |
|---|---|---|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (15)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|