KEGG   Homo sapiens (human): 5861
Entry
5861              CDS       T01001                                 
Symbol
RAB1A, RAB1, YPT1
Name
(RefSeq) RAB1A, member RAS oncogene family
  KO
K07874  Ras-related protein Rab-1A
Organism
hsa  Homo sapiens (human)
Pathway
hsa04140  Autophagy - animal
hsa05014  Amyotrophic lateral sclerosis
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05130  Pathogenic Escherichia coli infection
hsa05134  Legionellosis
Network
nt06125  Membrane trafficking (bacteria)
nt06413  Autophagy
nt06464  Amyotrophic lateral sclerosis
  Element
N01142  C9orf72-mediated autophagy initiation
N01143  Mutation-inactivated C9orf72 to C9orf72-mediated autophagy initiation
N01291  TRAPPI-RAB1 signaling pathway
N01292  Escherichia EspG to RAB1 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    5861 (RAB1A)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    5861 (RAB1A)
   05134 Legionellosis
    5861 (RAB1A)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    5861 (RAB1A)
   05022 Pathways of neurodegeneration - multiple diseases
    5861 (RAB1A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    5861 (RAB1A)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5861 (RAB1A)
   04031 GTP-binding proteins [BR:hsa04031]
    5861 (RAB1A)
Membrane trafficking [BR:hsa04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   Rab GTPases
    5861 (RAB1A)
 Autophagy
  Other autophagy associated proteins
    5861 (RAB1A)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   5861 (RAB1A)
  Exosomal proteins of other body fluids (saliva and urine)
   5861 (RAB1A)
  Exosomal proteins of colorectal cancer cells
   5861 (RAB1A)
GTP-binding proteins [BR:hsa04031]
 Small (monomeric) G-proteins
  Rab Family
   Rab1/35 [OT]
    5861 (RAB1A)
SSDB
Motif
Pfam: Ras Roc Arf RsgA_GTPase GTP_EFTU MMR_HSR1 Gtr1_RagA SRPRB AAA FeoB_N PduV-EutP AAA_16 AAA_7 AAA_22 AAA_29 ABC_tran Septin AAA_5 LANC_like TniB Dioxygenase_N
Other DBs
NCBI-GeneID: 5861
NCBI-ProteinID: NP_004152
OMIM: 179508
HGNC: 9758
Ensembl: ENSG00000138069
Pharos: P62820(Tbio)
UniProt: P62820 Q5U0I6
Structure
Position
2:complement(65086854..65130106)
AA seq 205 aa
MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
KLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKL
LVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGA
TAGGAEKSNVKIQSTPVKQSGGGCC
NT seq 618 nt   +upstreamnt  +downstreamnt
atgtccagcatgaatcccgaatatgattatttattcaagttacttctgattggcgactca
ggggttggaaagtcttgccttcttcttaggtttgcagatgatacatatacagaaagctac
atcagcacaattggtgtggatttcaaaataagaactatagagttagacgggaaaacaatc
aagcttcaaatatgggacacagcaggccaggaaagatttcgaacaatcacctccagttat
tacagaggagcccatggcatcatagttgtgtatgatgtgacagatcaggagtccttcaat
aatgttaaacagtggctgcaggaaatagatcgttatgccagtgaaaatgtcaacaaattg
ttggtagggaacaaatgtgatctgaccacaaagaaagtagtagactacacaacagcgaag
gaatttgctgattcccttggaattccgtttttggaaaccagtgctaagaatgcaacgaat
gtagaacagtctttcatgacgatggcagctgagattaaaaagcgaatgggtcccggagca
acagctggtggtgctgagaagtccaatgttaaaattcagagcactccagtcaagcagtca
ggtggaggttgctgctaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (5)   
   KEGG PATHWAY (5)   
Network (4)   
   KEGG NETWORK (4)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (110)   
   KEGG ORTHOLOGY (1)   
   RefGene (94)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
   PHAROS (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (35)   
   RefSeq(nuc) (3)   
   GenBank (16)   
   EMBL (16)   
3D Structure (11)   
   PDB (11)   
Protein domain (21)   
   Pfam (21)   
All databases (198)   

Download RDF
DBGET integrated database retrieval system