KEGG   Homo sapiens (human): 5861
Entry
5861              CDS       T01001                                 
Symbol
RAB1A, RAB1, YPT1
Name
(RefSeq) RAB1A, member RAS oncogene family
  KO
K07874  Ras-related protein Rab-1A
Organism
hsa  Homo sapiens (human)
Pathway
hsa04140  Autophagy - animal
hsa05014  Amyotrophic lateral sclerosis
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05130  Pathogenic Escherichia coli infection
hsa05134  Legionellosis
Network
nt06180  Pathogenic Escherichia coli
nt06464  Amyotrophic lateral sclerosis
nt06466  Pathways of neurodegeneration
nt06532  Autophagy
  Element
N01142  C9orf72-mediated autophagy initiation
N01143  Mutation-inactivated C9orf72 to C9orf72-mediated autophagy initiation
N01291  TRAPPI-RAB1 signaling pathway
N01292  Escherichia EspG to RAB1 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    5861 (RAB1A)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    5861 (RAB1A)
   05134 Legionellosis
    5861 (RAB1A)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    5861 (RAB1A)
   05022 Pathways of neurodegeneration - multiple diseases
    5861 (RAB1A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    5861 (RAB1A)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5861 (RAB1A)
   04031 GTP-binding proteins [BR:hsa04031]
    5861 (RAB1A)
Membrane trafficking [BR:hsa04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   Rab GTPases
    5861 (RAB1A)
 Autophagy
  Other autophagy associated proteins
    5861 (RAB1A)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   5861 (RAB1A)
  Exosomal proteins of other body fluids (saliva and urine)
   5861 (RAB1A)
  Exosomal proteins of colorectal cancer cells
   5861 (RAB1A)
GTP-binding proteins [BR:hsa04031]
 Small (monomeric) G-proteins
  Rab Family
   Rab1/35 [OT]
    5861 (RAB1A)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 Gtr1_RagA SRPRB FeoB_N AAA ABC_tran AAA_7 PduV-EutP AAA_16 LANC_like AAA_29 Septin AAA_22 AAA_5 CRAL_TRIO_2
Other DBs
NCBI-GeneID: 5861
NCBI-ProteinID: NP_004152
OMIM: 179508
HGNC: 9758
Ensembl: ENSG00000138069
UniProt: P62820 Q5U0I6
Structure
Position
2:complement(65086854..65130106)
AA seq 205 aa
MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
KLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKL
LVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGA
TAGGAEKSNVKIQSTPVKQSGGGCC
NT seq 618 nt   +upstreamnt  +downstreamnt
atgtccagcatgaatcccgaatatgattatttattcaagttacttctgattggcgactca
ggggttggaaagtcttgccttcttcttaggtttgcagatgatacatatacagaaagctac
atcagcacaattggtgtggatttcaaaataagaactatagagttagacgggaaaacaatc
aagcttcaaatatgggacacagcaggccaggaaagatttcgaacaatcacctccagttat
tacagaggagcccatggcatcatagttgtgtatgatgtgacagatcaggagtccttcaat
aatgttaaacagtggctgcaggaaatagatcgttatgccagtgaaaatgtcaacaaattg
ttggtagggaacaaatgtgatctgaccacaaagaaagtagtagactacacaacagcgaag
gaatttgctgattcccttggaattccgtttttggaaaccagtgctaagaatgcaacgaat
gtagaacagtctttcatgacgatggcagctgagattaaaaagcgaatgggtcccggagca
acagctggtggtgctgagaagtccaatgttaaaattcagagcactccagtcaagcagtca
ggtggaggttgctgctaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (108)   
   RefGene (94)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (36)   
   RefSeq(nuc) (4)   
   GenBank (16)   
   EMBL (16)   
3D Structure (15)   
   PDB (15)   
Protein domain (20)   
   Pfam (20)   
All databases (187)   

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