KEGG   PATHWAY: hsa00052
Entry
hsa00052                    Pathway                                
Name
Galactose metabolism - Homo sapiens (human)
Class
Metabolism; Carbohydrate metabolism
Pathway map
hsa00052  Galactose metabolism
hsa00052

Module
hsa_M00554  Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:hsa00052]
hsa_M00632  Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:hsa00052]
Network
  Element
N00847  Galactose degradation
Drug
D00216  Acarbose (JAN/USAN/INN)
D00625  Miglitol (JP18/USAN/INN)
D01665  Voglibose (JP18/USAN/INN)
D01688  Epalrestat (JP18/INN)
D01715  Risarestat (INN)
D01842  Fidarestat (JAN/INN)
D02323  Tolrestat (USAN/INN)
D02328  Zopolrestat (USAN/INN)
D02835  Alrestatin sodium (USAN)
D03207  Alglucosidase alfa (USAN/INN)
D03342  Camiglibose (USAN)
D03803  Lidorestat (USAN)
D03805  Minalrestat (USAN/INN)
D03806  Ponalrestat (USAN/INN)
D03807  Zenarestat (USAN/INN)
D05893  Sorbinil (USAN/INN)
D06403  Ranirestat (JAN/INN)
D09605  Duvoglustat (USAN/INN)
D09606  Duvoglustat hydrochloride (USAN)
D09779  Emiglitate (JAN/INN)
D11744  Avalglucosidase alfa (USAN/INN)
D11798  Cipaglucosidase alfa (USAN)
D11828  Clervonafusp alfa (USAN/INN)
D12384  Govorestat (USAN/INN)
D12390  Caficrestat (USAN/INN)
Other DBs
GO: 0006012
Organism
Homo sapiens (human) [GN:hsa]
Gene
130589  GALM; galactose mutarotase [KO:K01785] [EC:5.1.3.3]
2584  GALK1; galactokinase 1 [KO:K00849] [EC:2.7.1.6]
2592  GALT; galactose-1-phosphate uridylyltransferase [KO:K00965] [EC:2.7.7.12]
2582  GALE; UDP-galactose-4-epimerase [KO:K01784] [EC:5.1.3.2]
7360  UGP2; UDP-glucose pyrophosphorylase 2 [KO:K00963] [EC:2.7.7.9]
5236  PGM1; phosphoglucomutase 1 [KO:K01835] [EC:5.4.2.2]
55276  PGM2; phosphoglucomutase 2 [KO:K15779] [EC:5.4.2.2 5.4.2.7]
3101  HK3; hexokinase 3 [KO:K00844] [EC:2.7.1.1]
3098  HK1; hexokinase 1 [KO:K00844] [EC:2.7.1.1]
3099  HK2; hexokinase 2 [KO:K00844] [EC:2.7.1.1]
80201  HKDC1; hexokinase domain containing 1 [KO:K00844] [EC:2.7.1.1]
2645  GCK; glucokinase [KO:K12407] [EC:2.7.1.2]
2538  G6PC1; glucose-6-phosphatase catalytic subunit 1 [KO:K01084] [EC:3.1.3.9]
57818  G6PC2; glucose-6-phosphatase catalytic subunit 2 [KO:K01084] [EC:3.1.3.9]
92579  G6PC3; glucose-6-phosphatase catalytic subunit 3 [KO:K01084] [EC:3.1.3.9]
2720  GLB1; galactosidase beta 1 [KO:K12309] [EC:3.2.1.23]
3938  LCT; lactase [KO:K01229] [EC:3.2.1.108 3.2.1.62]
3906  LALBA; lactalbumin alpha [KO:K00704] [EC:2.4.1.22]
2683  B4GALT1; beta-1,4-galactosyltransferase 1 [KO:K07966] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
8704  B4GALT2; beta-1,4-galactosyltransferase 2 [KO:K07967] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
2717  GLA; galactosidase alpha [KO:K01189] [EC:3.2.1.22]
231  AKR1B1; aldo-keto reductase family 1 member B [KO:K00011] [EC:1.1.1.21]
57016  AKR1B10; aldo-keto reductase family 1 member B10 [KO:K00011] [EC:1.1.1.21]
441282  AKR1B15; aldo-keto reductase family 1 member B15 [KO:K00011] [EC:1.1.1.21]
5213  PFKM; phosphofructokinase, muscle [KO:K00850] [EC:2.7.1.11]
5214  PFKP; phosphofructokinase, platelet [KO:K00850] [EC:2.7.1.11]
5211  PFKL; phosphofructokinase, liver type [KO:K00850] [EC:2.7.1.11]
8972  MGAM; maltase-glucoamylase [KO:K12047] [EC:3.2.1.20 3.2.1.3]
93432  MGAM2; maltase-glucoamylase 2 (putative) [KO:K12047] [EC:3.2.1.20 3.2.1.3]
2548  GAA; alpha glucosidase [KO:K12316] [EC:3.2.1.20]
2595  GANC; glucosidase alpha, neutral C [KO:K12317] [EC:3.2.1.20]
6476  SI; sucrase-isomaltase [KO:K01203] [EC:3.2.1.48 3.2.1.10]
Compound
C00029  UDP-glucose
C00031  D-Glucose
C00052  UDP-alpha-D-galactose
C00085  D-Fructose 6-phosphate
C00089  Sucrose
C00095  D-Fructose
C00103  D-Glucose 1-phosphate
C00111  Glycerone phosphate
C00116  Glycerol
C00118  D-Glyceraldehyde 3-phosphate
C00124  D-Galactose
C00137  myo-Inositol
C00159  D-Mannose
C00243  Lactose
C00267  alpha-D-Glucose
C00446  alpha-D-Galactose 1-phosphate
C00492  Raffinose
C00577  D-Glyceraldehyde
C00668  alpha-D-Glucose 6-phosphate
C00794  D-Sorbitol
C00795  D-Tagatose
C00880  D-Galactonate
C00984  alpha-D-Galactose
C01097  D-Tagatose 6-phosphate
C01113  D-Galactose 6-phosphate
C01132  N-Acetyl-D-galactosamine
C01216  2-Dehydro-3-deoxy-D-galactonate
C01235  alpha-D-Galactosyl-(1->3)-1D-myo-inositol
C01286  2-Dehydro-3-deoxy-6-phospho-D-galactonate
C01613  Stachyose
C01697  Galactitol
C02262  D-Galactosamine
C02669  D-Galactono-1,5-lactone
C03383  D-Galactono-1,4-lactone
C03733  UDP-alpha-D-galactofuranose
C03785  D-Tagatose 1,6-bisphosphate
C05396  Lactose 6'-phosphate
C05399  Melibiitol
C05400  Epimelibiose
C05401  3-beta-D-Galactosyl-sn-glycerol
C05402  Melibiose
C05404  D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose
C05796  Galactan
C06311  Galactitol 1-phosphate
C06376  N-Acetyl-D-galactosamine 6-phosphate
C06377  D-Galactosamine 6-phosphate
Related
pathway
hsa00010  Glycolysis / Gluconeogenesis
hsa00030  Pentose phosphate pathway
hsa00040  Pentose and glucuronate interconversions
hsa00051  Fructose and mannose metabolism
hsa00520  Amino sugar and nucleotide sugar metabolism
KO pathway
ko00052   

  All links  
Network (1)   
   KEGG NETWORK (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG GENES (32)   
All databases (34)   

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