KEGG   PATHWAY: hsa00650
Entry
hsa00650                    Pathway                                

Name
Butanoate metabolism - Homo sapiens (human)
Class
Metabolism; Carbohydrate metabolism
Pathway map
hsa00650  Butanoate metabolism
hsa00650

Module
hsa_M00027  GABA (gamma-Aminobutyrate) shunt [PATH:hsa00650]
Organism
Homo sapiens (human) [GN:hsa]
Gene
39  ACAT2; acetyl-CoA acetyltransferase 2 [KO:K00626] [EC:2.3.1.9]
38  ACAT1; acetyl-CoA acetyltransferase 1 [KO:K00626] [EC:2.3.1.9]
3033  HADH; hydroxyacyl-CoA dehydrogenase [KO:K00022] [EC:1.1.1.35]
3030  HADHA; hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha [KO:K07515] [EC:4.2.1.17 1.1.1.211]
1962  EHHADH; enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase [KO:K07514] [EC:4.2.1.17 1.1.1.35 5.3.3.8]
1892  ECHS1; enoyl-CoA hydratase, short chain 1 [KO:K07511] [EC:4.2.1.17]
35  ACADS; acyl-CoA dehydrogenase short chain [KO:K00248] [EC:1.3.8.1]
116285  ACSM1; acyl-CoA synthetase medium chain family member 1 [KO:K23756] [EC:6.2.1.2]
123876  ACSM2A; acyl-CoA synthetase medium chain family member 2A [KO:K01896] [EC:6.2.1.2]
341392  ACSM4; acyl-CoA synthetase medium chain family member 4 [KO:K01896] [EC:6.2.1.2]
54988  ACSM5; acyl-CoA synthetase medium chain family member 5 [KO:K01896] [EC:6.2.1.2]
6296  ACSM3; acyl-CoA synthetase medium chain family member 3 [KO:K01896] [EC:6.2.1.2]
348158  ACSM2B; acyl-CoA synthetase medium chain family member 2B [KO:K01896] [EC:6.2.1.2]
142827  ACSM6; acyl-CoA synthetase medium chain family member 6 [KO:K01896] [EC:6.2.1.2]
79944  L2HGDH; L-2-hydroxyglutarate dehydrogenase [KO:K00109] [EC:1.1.99.2]
2571  GAD1; glutamate decarboxylase 1 [KO:K01580] [EC:4.1.1.15]
2572  GAD2; glutamate decarboxylase 2 [KO:K01580] [EC:4.1.1.15]
18  ABAT; 4-aminobutyrate aminotransferase [KO:K13524] [EC:2.6.1.19 2.6.1.22]
7915  ALDH5A1; aldehyde dehydrogenase 5 family member A1 [KO:K00139] [EC:1.2.1.24]
3157  HMGCS1; 3-hydroxy-3-methylglutaryl-CoA synthase 1 [KO:K01641] [EC:2.3.3.10]
3158  HMGCS2; 3-hydroxy-3-methylglutaryl-CoA synthase 2 [KO:K01641] [EC:2.3.3.10]
3155  HMGCL; 3-hydroxy-3-methylglutaryl-CoA lyase [KO:K01640] [EC:4.1.3.4]
54511  HMGCLL1; 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1 [KO:K01640] [EC:4.1.3.4]
5019  OXCT1; 3-oxoacid CoA-transferase 1 [KO:K01027] [EC:2.8.3.5]
64064  OXCT2; 3-oxoacid CoA-transferase 2 [KO:K01027] [EC:2.8.3.5]
65985  AACS; acetoacetyl-CoA synthetase [KO:K01907] [EC:6.2.1.16]
622  BDH1; 3-hydroxybutyrate dehydrogenase 1 [KO:K00019] [EC:1.1.1.30]
56898  BDH2; 3-hydroxybutyrate dehydrogenase 2 [KO:K00019] [EC:1.1.1.30]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00042  Succinate
C00091  Succinyl-CoA
C00122  Fumarate
C00136  Butanoyl-CoA
C00164  Acetoacetate
C00232  Succinate semialdehyde
C00246  Butanoic acid
C00332  Acetoacetyl-CoA
C00334  4-Aminobutanoate
C00356  (S)-3-Hydroxy-3-methylglutaryl-CoA
C00497  (R)-Malate
C00741  Diacetyl
C00810  (R)-Acetoin
C00877  Crotonoyl-CoA
C00989  4-Hydroxybutanoic acid
C01089  (R)-3-Hydroxybutanoate
C01144  (S)-3-Hydroxybutanoyl-CoA
C01384  Maleic acid
C01412  Butanal
C01769  (S)-Acetoin
C02331  Vinylacetyl-CoA
C02411  Glutaconyl-1-CoA
C02527  Butanoylphosphate
C02630  2-Hydroxyglutarate
C03044  (R,R)-Butane-2,3-diol
C03046  (S,S)-Butane-2,3-diol
C03058  2-Hydroxyglutaryl-CoA
C03561  (R)-3-Hydroxybutanoyl-CoA
C04546  (R)-3-((R)-3-Hydroxybutanoyloxy)butanoate
C06010  (S)-2-Acetolactate
C06142  1-Butanol
C06143  Poly-beta-hydroxybutyrate
C06144  3-Butynoate
C06145  3-Butyn-1-al
C06146  3-Butyn-1-ol
C11062  4-Hydroxybutyryl-CoA
C20657  meso-2,3-Butanediol
C21390  Butane
Related
pathway
hsa00010  Glycolysis / Gluconeogenesis
hsa00020  Citrate cycle (TCA cycle)
hsa00072  Synthesis and degradation of ketone bodies
hsa00250  Alanine, aspartate and glutamate metabolism
hsa00330  Arginine and proline metabolism
hsa00620  Pyruvate metabolism
hsa00750  Vitamin B6 metabolism
KO pathway
ko00650   

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