#=GF ID FXMRP1_C_core
#=GF AC PF12235.9
#=GF DE Fragile X-related 1 protein core C terminal
#=GF PI FXR1P_C;
#=GF AU Assefa S;0000-0003-2178-533X
#=GF AU Gavin OL;
#=GF SE PFAM-B_2701 (release 23.0)
#=GF GA 29.60 29.60;
#=GF TC 29.80 29.80;
#=GF NC 29.40 28.70;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 47079205 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 16000371
#=GF RT The RNA-binding protein fragile X-related 1 regulates somite
#=GF RT formation in Xenopus laevis.
#=GF RA Huot ME, Bisson N, Davidovic L, Mazroui R, Labelle Y, Moss T,
#=GF RA Khandjian EW;
#=GF RL Mol Biol Cell. 2005;16:4350-4361.
#=GF RN [2]
#=GF RM 16707258
#=GF RT mRNPs, polysomes or granules: FMRP in neuronal protein
#=GF RT synthesis.
#=GF RA Zalfa F, Achsel T, Bagni C;
#=GF RL Curr Opin Neurobiol. 2006;16:265-269.
#=GF RN [3]
#=GF RM 20463240
#=GF RT Short- and long-term memory are modulated by multiple isoforms
#=GF RT of the fragile X mental retardation protein.
#=GF RA Banerjee P, Schoenfeld BP, Bell AJ, Choi CH, Bradley MP, Hinchey
#=GF RA P, Kollaros M, Park JH, McBride SM, Dockendorff TC;
#=GF RL J Neurosci. 2010;30:6782-6792.
#=GF DR INTERPRO; IPR022034;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC This domain family is found in eukaryotes, and is typically
#=GF CC between 126 and 160 amino acids in length. The family is found
#=GF CC in association with Pfam:PF05641, Pfam:PF00013. This family is
#=GF CC the core C terminal region of the fragile X related 1 proteins
#=GF CC FXR1P, FXR2 and FMR1. These different proteins have different
#=GF CC regions at their very C-terminus. The Glutamine-arginine rich
#=GF CC region facilitates protein interactions [3]. This family
#=GF CC contains two blocks of RGG repeats that bind to G-quartet
#=GF CC sequences in a wide variety of mRNAs [2].
#=GF SQ 1195
#=GS A0A2K6FRI5_PROCO/329-351 AC A0A2K6FRI5.1
#=GS A0A3Q1F2Q2_9TELE/359-468 AC A0A3Q1F2Q2.1
#=GS A0A2Y9JF56_ENHLU/354-380 AC A0A2Y9JF56.1
#=GS A0A2K5NFP6_CERAT/305-331 AC A0A2K5NFP6.1
#=GS H2QNT0_PANTR/512-590 AC H2QNT0.2
#=GS A0A452DKD5_CAPHI/420-542 AC A0A452DKD5.1
#=GS A0A0V1BAY0_TRISP/340-480 AC A0A0V1BAY0.1
#=GS A0A3Q1M5A0_BOVIN/378-456 AC A0A3Q1M5A0.1
#=GS A0A2K6LRU0_RHIBE/354-405 AC A0A2K6LRU0.1
#=GS W5K1B5_ASTMX/354-478 AC W5K1B5.1
#=GS A0A1S3SD84_SALSA/375-488 AC A0A1S3SD84.1
#=GS A0A1A9VAU8_GLOAU/357-459 AC A0A1A9VAU8.1
#=GS A0A3B3W2U2_9TELE/354-490 AC A0A3B3W2U2.1
#=GS A0A2D0RIU1_ICTPU/331-455 AC A0A2D0RIU1.1
#=GS H3ABK7_LATCH/326-446 AC H3ABK7.1
#=GS A0A383ZVX7_BALAS/399-487 AC A0A383ZVX7.1
#=GS A0A2K5NFH4_CERAT/335-466 AC A0A2K5NFH4.1
#=GS A0A087RJ11_APTFO/320-451 AC A0A087RJ11.1
#=GS K7CYT7_PANTR/379-456 AC K7CYT7.1
#=GS A0A3B3SY02_9TELE/360-488 AC A0A3B3SY02.1
#=GS A0A2I2ZYL2_GORGO/379-456 AC A0A2I2ZYL2.1
#=GS A0A2Y9MCL8_DELLE/420-509 AC A0A2Y9MCL8.1
#=GS A0A2K5TM89_MACFA/338-372 AC A0A2K5TM89.1
#=GS A0A3Q7UXY6_URSAR/420-542 AC A0A3Q7UXY6.1
#=GS A0A3Q2GSI8_HORSE/375-401 AC A0A3Q2GSI8.1
#=GS A0A2R9BJP6_PANPA/330-399 AC A0A2R9BJP6.1
#=GS M4AB72_XIPMA/370-496 AC M4AB72.1
#=GS A0A3B3Y4R6_9TELE/362-500 AC A0A3B3Y4R6.1
#=GS A0A3B4GNB0_9CICH/370-476 AC A0A3B4GNB0.1
#=GS A0A2U3XII8_LEPWE/379-456 AC A0A2U3XII8.1
#=GS F6RX02_CALJA/399-521 AC F6RX02.2
#=GS A0A443R1W7_9ACAR/433-575 AC A0A443R1W7.1
#=GS F1RQ52_PIG/314-399 AC F1RQ52.3
#=GS A0A2K6BVC9_MACNE/294-371 AC A0A2K6BVC9.1
#=GS A0A1D5PL30_CHICK/354-383 AC A0A1D5PL30.1
#=GS A0A2Y9RCM1_TRIMA/420-542 AC A0A2Y9RCM1.1
#=GS A0A2K5D5T5_AOTNA/354-380 AC A0A2K5D5T5.1
#=GS A0A452C4C4_BALAS/378-456 AC A0A452C4C4.1
#=GS A0A2K5U918_MACFA/399-521 AC A0A2K5U918.1
#=GS A0A402FGL2_9SAUR/364-476 AC A0A402FGL2.1
#=GS H2M8G1_ORYLA/354-484 AC H2M8G1.2
#=GS A0A452RW72_URSAM/343-403 AC A0A452RW72.1
#=GS C3ZEH7_BRAFL/376-513 AC C3ZEH7.1
#=GS A0A3B4EQ18_9CICH/348-478 AC A0A3B4EQ18.1
#=GS A0A3Q3E2A6_9LABR/372-484 AC A0A3Q3E2A6.1
#=GS G3V0J0_HUMAN/397-519 AC G3V0J0.1
#=GS A0A3Q7T619_VULVU/335-445 AC A0A3Q7T619.1
#=GS A0A455BTZ6_PHYMC/350-427 AC A0A455BTZ6.1
#=GS A0A3Q3M077_9TELE/356-488 AC A0A3Q3M077.1
#=GS G3X2U9_SARHA/395-472 AC G3X2U9.1
#=GS A0A3B4ZWP3_9TELE/343-451 AC A0A3B4ZWP3.1
#=GS A0A2I3GTR2_NOMLE/260-281 AC A0A2I3GTR2.1
#=GS A0A3B3Z5X1_9TELE/370-486 AC A0A3B3Z5X1.1
#=GS A0A340YC18_LIPVE/269-295 AC A0A340YC18.1
#=GS A0A4D9FBV4_9SAUR/375-502 AC A0A4D9FBV4.1
#=GS A0A3B3R9M4_9TELE/356-478 AC A0A3B3R9M4.1
#=GS A0A2U3ZUI2_ODORO/317-439 AC A0A2U3ZUI2.1
#=GS A0A2Y9JMZ5_ENHLU/354-485 AC A0A2Y9JMZ5.1
#=GS G1RSC8_NOMLE/420-542 AC G1RSC8.3
#=GS A0A1U7QAP8_MESAU/354-381 AC A0A1U7QAP8.1
#=GS A0A3Q3KZV7_9TELE/349-477 AC A0A3Q3KZV7.1
#=GS G5B5D2_HETGA/281-406 AC G5B5D2.1
#=GS E9QG02_DANRE/370-478 AC E9QG02.1
#=GS A0A1S3A0Z9_ERIEU/420-542 AC A0A1S3A0Z9.1
#=GS A0A3B4XU30_SERLL/343-453 AC A0A3B4XU30.1
#=GS A0A2K5DAY8_AOTNA/420-542 AC A0A2K5DAY8.1
#=GS A0A383ZV98_BALAS/420-509 AC A0A383ZV98.1
#=GS F7FHC1_MONDO/420-547 AC F7FHC1.2
#=GS A0A1D5PDA7_CHICK/379-458 AC A0A1D5PDA7.2
#=GS A0A2K6PXZ2_RHIRO/378-456 AC A0A2K6PXZ2.1
#=GS M3XTA9_MUSPF/378-456 AC M3XTA9.1
#=GS A0A3M0JM23_HIRRU/354-485 AC A0A3M0JM23.1
#=GS A0A087UUQ0_9ARAC/355-459 AC A0A087UUQ0.1
#=GS A0A2K5N0S4_CERAT/400-519 AC A0A2K5N0S4.1
#=GS A0A452RV51_URSAM/343-479 AC A0A452RV51.1
#=GS A0A2K5QFB4_CEBCA/337-468 AC A0A2K5QFB4.1
#=GS FXR1_HUMAN/378-456 AC P51114.3
#=GS A0A2K5D5V8_AOTNA/379-456 AC A0A2K5D5V8.1
#=GS A0A1L1RLY8_CHICK/357-436 AC A0A1L1RLY8.2
#=GS E9PFF5_HUMAN/305-331 AC E9PFF5.1
#=GS A0A2R9BNE2_PANPA/297-323 AC A0A2R9BNE2.1
#=GS I3M6H4_ICTTR/364-490 AC I3M6H4.1
#=GS A0A2K5N173_CERAT/335-457 AC A0A2K5N173.1
#=GS A0A2Y9KSN9_ENHLU/420-508 AC A0A2Y9KSN9.1
#=GS A0A2U3VSV8_ODORO/269-400 AC A0A2U3VSV8.1
#=GS A0A0D9R4K7_CHLSB/399-521 AC A0A0D9R4K7.1
#=GS A0A3B3XMT9_9TELE/356-493 AC A0A3B3XMT9.1
#=GS A0A1B0BRU4_9MUSC/368-471 AC A0A1B0BRU4.1
#=GS A0A452C4M8_BALAS/379-456 AC A0A452C4M8.1
#=GS A0A2K5PEX9_CEBCA/332-459 AC A0A2K5PEX9.1
#=GS L9L0L4_TUPCH/339-464 AC L9L0L4.1
#=GS A0A091EEE8_CORBR/321-452 AC A0A091EEE8.1
#=GS A0A2D0RTV2_ICTPU/354-484 AC A0A2D0RTV2.1
#=GS F7CVY9_ORNAN/269-297 AC F7CVY9.1
#=GS A0A1L8F2W4_XENLA/354-480 AC A0A1L8F2W4.1
#=GS I3KPT7_ORENI/370-478 AC I3KPT7.1
#=GS A0A2K5Z8K2_MANLE/399-521 AC A0A2K5Z8K2.1
#=GS W5QHM0_SHEEP/354-382 AC W5QHM0.1
#=GS A0A1S3N7N5_SALSA/359-474 AC A0A1S3N7N5.1
#=GS A0A1A9X406_9MUSC/329-454 AC A0A1A9X406.1
#=GS A0A3Q3M3S9_9LABR/342-476 AC A0A3Q3M3S9.1
#=GS A0A2K6BRC3_MACNE/364-491 AC A0A2K6BRC3.1
#=GS I0FIR3_MACMU/420-542 AC I0FIR3.1
#=GS A0A2Y9MZ11_DELLE/354-485 AC A0A2Y9MZ11.1
#=GS FMR1_DROME/362-490 AC Q9NFU0.1
#=GS A0A2Y9F8R6_PHYMC/378-456 AC A0A2Y9F8R6.1
#=GS A0A493TRX1_ANAPP/354-383 AC A0A493TRX1.1
#=GS F6XQE7_CANLF/379-456 AC F6XQE7.1
#=GS A0A3Q0FQH0_ALLSI/444-568 AC A0A3Q0FQH0.1
#=GS B4QVU1_DROSI/359-486 AC B4QVU1.1
#=GS FMR1_HUMAN/420-547 AC Q06787.1
#=GS FMR1_HUMAN/420-547 DR PDB; 5DE8 D; 6-19;
#=GS FMR1_HUMAN/420-547 DR PDB; 5UWO D; 11-20;
#=GS FMR1_HUMAN/420-547 DR PDB; 2QND A; 139-144;
#=GS FMR1_HUMAN/420-547 DR PDB; 5DE5 B; 5-18;
#=GS FMR1_HUMAN/420-547 DR PDB; 5DEA B; 5-18;
#=GS FMR1_HUMAN/420-547 DR PDB; 5DE5 D; 6-18;
#=GS FMR1_HUMAN/420-547 DR PDB; 5UWJ D; 427-437;
#=GS FMR1_HUMAN/420-547 DR PDB; 5DEA D; 5-18;
#=GS FMR1_HUMAN/420-547 DR PDB; 2QND B; 139-144;
#=GS FMR1_HUMAN/420-547 DR PDB; 2LA5 B; 3-17;
#=GS FMR1_HUMAN/420-547 DR PDB; 5DE8 B; 5-18;
#=GS A0A091WHN3_OPIHO/321-452 AC A0A091WHN3.1
#=GS A0A3B4CST7_PYGNA/386-512 AC A0A3B4CST7.1
#=GS A0A493U057_ANAPP/354-481 AC A0A493U057.1
#=GS A0A1W4VN56_DROFC/359-489 AC A0A1W4VN56.1
#=GS A0A2K6A360_MANLE/338-468 AC A0A2K6A360.1
#=GS A0A3Q2CA28_CYPVA/350-484 AC A0A3Q2CA28.1
#=GS FXR1_XENTR/354-485 AC Q5BJ56.2
#=GS A0A096P2R4_PAPAN/364-491 AC A0A096P2R4.1
#=GS A0A2Y9L6D9_ENHLU/399-487 AC A0A2Y9L6D9.1
#=GS W5JYG9_ASTMX/355-478 AC W5JYG9.2
#=GS H2S708_TAKRU/356-493 AC H2S708.2
#=GS A0A2Y9R6Y3_TRIMA/420-542 AC A0A2Y9R6Y3.1
#=GS A0A3P8TDE5_AMPPE/360-508 AC A0A3P8TDE5.1
#=GS I3LAK5_PIG/379-456 AC I3LAK5.2
#=GS A0A3P9A0S4_ESOLU/337-463 AC A0A3P9A0S4.1
#=GS A0A2Y9KSN5_ENHLU/420-542 AC A0A2Y9KSN5.1
#=GS A0A2I3HRU3_NOMLE/397-519 AC A0A2I3HRU3.1
#=GS A0A0V1L6V8_9BILA/364-485 AC A0A0V1L6V8.1
#=GS A0A3Q1CSU4_AMPOC/381-502 AC A0A3Q1CSU4.1
#=GS A0A0V1BB02_TRISP/340-450 AC A0A0V1BB02.1
#=GS A0A2K6PXZ1_RHIRO/354-380 AC A0A2K6PXZ1.1
#=GS F7BZ50_HORSE/364-491 AC F7BZ50.2
#=GS A0A2Y9RKW3_TRIMA/168-299 AC A0A2Y9RKW3.1
#=GS A0A1L1RLY8_CHICK/332-362 AC A0A1L1RLY8.2
#=GS A0A2Y9RB70_TRIMA/294-371 AC A0A2Y9RB70.1
#=GS F1MXQ7_BOVIN/399-521 AC F1MXQ7.3
#=GS A0A091VP35_NIPNI/338-465 AC A0A091VP35.1
#=GS A0A3B4UL92_SERDU/360-498 AC A0A3B4UL92.1
#=GS A0A067QSD0_ZOONE/403-431 AC A0A067QSD0.1
#=GS G3SF62_GORGO/269-295 AC G3SF62.2
#=GS A0A1U7QCZ1_MESAU/354-485 AC A0A1U7QCZ1.1
#=GS F7I1J4_CALJA/314-391 AC F7I1J4.2
#=GS I3J763_ORENI/354-489 AC I3J763.1
#=GS A0A2J7QG40_9NEOP/358-495 AC A0A2J7QG40.1
#=GS A0A452J2C0_9SAUR/356-483 AC A0A452J2C0.1
#=GS H0Z2U8_TAEGU/381-503 AC H0Z2U8.1
#=GS A0A1U8DQ50_ALLSI/342-461 AC A0A1U8DQ50.2
#=GS A0A2U3VSU4_ODORO/379-456 AC A0A2U3VSU4.1
#=GS A0A2K5N0P3_CERAT/334-441 AC A0A2K5N0P3.1
#=GS A3KMH8_XENLA/354-485 AC A3KMH8.1
#=GS A0A2Y9F7P1_PHYMC/354-380 AC A0A2Y9F7P1.1
#=GS G3S4X0_GORGO/391-513 AC G3S4X0.2
#=GS A0A1S2ZNU6_ERIEU/364-491 AC A0A1S2ZNU6.1
#=GS A0A0A0AUB4_CHAVO/338-465 AC A0A0A0AUB4.1
#=GS A0A1S3EY36_DIPOR/269-397 AC A0A1S3EY36.1
#=GS A0A3B3R950_9TELE/360-486 AC A0A3B3R950.1
#=GS A0A2U3VT43_ODORO/354-380 AC A0A2U3VT43.1
#=GS A0A3P8UQ81_CYNSE/356-480 AC A0A3P8UQ81.1
#=GS U3IRF4_ANAPP/354-485 AC U3IRF4.2
#=GS A0A2U4C8C7_TURTR/354-380 AC A0A2U4C8C7.1
#=GS H3AT50_LATCH/354-478 AC H3AT50.1
#=GS A0A3Q2GZ80_HORSE/354-380 AC A0A3Q2GZ80.1
#=GS A0A383ZVB7_BALAS/420-542 AC A0A383ZVB7.1
#=GS A0A1U8BZ10_MESAU/354-485 AC A0A1U8BZ10.1
#=GS A0A2I4CEH6_9TELE/354-468 AC A0A2I4CEH6.1
#=GS A0A2I3S815_PANTR/322-399 AC A0A2I3S815.1
#=GS A0A2Y9JF56_ENHLU/379-456 AC A0A2Y9JF56.1
#=GS A0A3Q2WS58_HAPBU/353-492 AC A0A3Q2WS58.1
#=GS A0A1A9Y638_GLOFF/357-461 AC A0A1A9Y638.1
#=GS A0A498MYT5_LABRO/361-473 AC A0A498MYT5.1
#=GS A0A2I2V070_FELCA/399-526 AC A0A2I2V070.2
#=GS A0A060X5W8_ONCMY/354-488 AC A0A060X5W8.1
#=GS A0A3B4C9N5_PYGNA/370-482 AC A0A3B4C9N5.1
#=GS A0A2K6B2A2_MACNE/420-542 AC A0A2K6B2A2.1
#=GS H3C8L7_TETNG/91-211 AC H3C8L7.1
#=GS A0A1V4K3N8_PATFA/354-485 AC A0A1V4K3N8.1
#=GS A0A2I3GF21_NOMLE/370-438 AC A0A2I3GF21.1
#=GS A0A2R9BKH9_PANPA/512-590 AC A0A2R9BKH9.1
#=GS G1T7S6_RABIT/420-542 AC G1T7S6.1
#=GS A0A2K6BV35_MACNE/354-380 AC A0A2K6BV35.1
#=GS A0A2I3SP60_PANTR/488-514 AC A0A2I3SP60.1
#=GS A0A3Q7T624_VULVU/314-424 AC A0A3Q7T624.1
#=GS A0A340Y5K4_LIPVE/379-456 AC A0A340Y5K4.1
#=GS H7C4S4_HUMAN/1-57 AC H7C4S4.8
#=GS G1P059_MYOLU/354-486 AC G1P059.1
#=GS A0A1S3SD93_SALSA/370-483 AC A0A1S3SD93.1
#=GS A0A0P7WY25_SCLFO/360-472 AC A0A0P7WY25.1
#=GS A0A384D960_URSMA/269-400 AC A0A384D960.1
#=GS A0A1V4K3G7_PATFA/354-485 AC A0A1V4K3G7.1
#=GS A0A3B0JI74_DROGU/362-465 AC A0A3B0JI74.1
#=GS A0A2I3HM61_NOMLE/362-439 AC A0A2I3HM61.1
#=GS A0A1J1HLK0_9DIPT/934-1066 AC A0A1J1HLK0.1
#=GS A0A0Q3MEQ6_AMAAE/354-485 AC A0A0Q3MEQ6.1
#=GS G1MEG5_AILME/354-481 AC G1MEG5.1
#=GS H9G467_ANOCA/343-466 AC H9G467.2
#=GS A0A2Y9MXG8_DELLE/379-456 AC A0A2Y9MXG8.1
#=GS F1Q2U8_CANLF/420-542 AC F1Q2U8.2
#=GS A0A2Y9F778_PHYMC/354-485 AC A0A2Y9F778.1
#=GS A0A3Q1J5M9_ANATE/359-505 AC A0A3Q1J5M9.1
#=GS K7GSF4_PIG/420-542 AC K7GSF4.1
#=GS A0A2Y9EFU1_PHYMC/420-530 AC A0A2Y9EFU1.1
#=GS A0A2K6PY24_RHIRO/269-320 AC A0A2K6PY24.1
#=GS G3WIB4_SARHA/420-499 AC G3WIB4.1
#=GS A0A455ANB1_PHYMC/420-501 AC A0A455ANB1.1
#=GS A0A452RWD4_URSAM/388-510 AC A0A452RWD4.1
#=GS A0A2U4C2N6_TURTR/364-491 AC A0A2U4C2N6.1
#=GS A0A3Q0TDG2_AMPCI/354-485 AC A0A3Q0TDG2.1
#=GS A0A3B3R9A7_9TELE/355-481 AC A0A3B3R9A7.1
#=GS A0A2K5U8V6_MACFA/388-471 AC A0A2K5U8V6.1
#=GS A0A226N6R9_CALSU/345-414 AC A0A226N6R9.1
#=GS A0A0V0VX38_9BILA/340-480 AC A0A0V0VX38.1
#=GS A0A2Y9F6V1_PHYMC/354-485 AC A0A2Y9F6V1.1
#=GS A0A3Q2CNC3_CYPVA/337-445 AC A0A3Q2CNC3.1
#=GS A0A3B0JE91_DROGU/295-398 AC A0A3B0JE91.1
#=GS FXR1_MOUSE/354-485 AC Q61584.2
#=GS A0A1S3T642_SALSA/360-484 AC A0A1S3T642.1
#=GS A0A2K6UTB8_SAIBB/308-335 AC A0A2K6UTB8.1
#=GS G3R3A0_GORGO/305-331 AC G3R3A0.2
#=GS A0A3Q7THS3_URSAR/420-542 AC A0A3Q7THS3.1
#=GS A0A3P8THY1_AMPPE/370-478 AC A0A3P8THY1.1
#=GS H0WZ54_OTOGA/354-380 AC H0WZ54.1
#=GS A0A3B4GAG4_9CICH/356-491 AC A0A3B4GAG4.1
#=GS A0A2K6PY23_RHIRO/337-468 AC A0A2K6PY23.1
#=GS A0A3B5AKK7_9TELE/355-486 AC A0A3B5AKK7.1
#=GS A0A286Y176_CAVPO/354-380 AC A0A286Y176.1
#=GS A0A286ZS04_PIG/354-485 AC A0A286ZS04.1
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