KEGG   REACTION: R08392
Entry
R08392                      Reaction                               

Definition
Retinoate + NADPH + H+ + Oxygen <=> all-trans-4-Hydroxyretinoic acid + NADP+ + H2O
Equation
Comment
CYP1A1/2, CYP2A6, CYP2B6, CYP2C8/9/18, CYP3A4/5/7, CYP26, CYP2S1
Reaction class
RC00001  C00005_C00006
RC00723  C00777_C16677
Enzyme
1.14.13.-       1.14.14.1       1.14.14.-
Pathway
rn00830  Retinol metabolism
rn01100  Metabolic pathways
Orthology
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07409  cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
K07411  cytochrome P450 family 2 subfamily A [EC:1.14.14.1]
K07412  cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K07413  cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07420  cytochrome P450 family 2 subfamily S1 [EC:1.14.14.1]
K07424  cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07437  cytochrome P450 family 26 subfamily A
K12664  cytochrome P450 family 26 subfamily B
K12665  cytochrome P450 family 26 subfamily C
K17683  cytochrome P450 family 2 subfamily A6 [EC:1.14.13.-]
K17689  cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.13.-]
K17690  cytochrome P450 family 3 subfamily A5 [EC:1.14.14.1]
K17691  cytochrome P450 family 3 subfamily A7 [EC:1.14.14.1]
K17709  cytochrome P450 family 2 subfamily B6 [EC:1.14.13.-]
K17718  cytochrome P450 family 2 subfamily C8 [EC:1.14.14.1]
K17719  cytochrome P450 family 2 subfamily C9 [EC:1.14.14.51 1.14.14.52 1.14.14.53 1.14.14.-]
K17720  cytochrome P450 family 2 subfamily C18 [EC:1.14.14.1]

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