PCIDB

KNApSAcK Metabolite C00001397

Metabolite

KNApSAcK Entry

id C00001397
Name L-Tyrosine
CAS RN 60-18-4
Standard InChI InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1
Standard InChI (Main Layer) InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)

Cluster

Phytochemical cluster
KCF-S cluster No. 3303

Link

ChEMBL

By standard InChI CHEMBL925
By standard InChI Main Layer CHEMBL925 CHEMBL108615 CHEMBL1076637

KEGG

By LinkDB C00082

CTD

By CAS RN

Human Protein / Gene in interaction

17 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P49798 Regulator of G-protein signaling 4 Unclassified protein CHEMBL1076637 CHEMBL1794499 (1)
2 / 0
P41240 Tyrosine-protein kinase CSK Csk CHEMBL925 CHEMBL913342 (1)
0 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase CHEMBL925 CHEMBL885804 (1)
0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase CHEMBL925 CHEMBL885803 (1)
0 / 0
P43166 Carbonic anhydrase 7 Lyase CHEMBL925 CHEMBL889439 (1)
0 / 0
P00918 Carbonic anhydrase 2 Lyase CHEMBL925 CHEMBL1076637 CHEMBL889437 (1) CHEMBL885802 (1)
CHEMBL887924 (1) CHEMBL932482 (1)
CHEMBL970751 (1) CHEMBL953311 (1)
CHEMBL953312 (1) CHEMBL1017972 (1)
CHEMBL1067709 (1) CHEMBL1106967 (2)
CHEMBL2156561 (2) CHEMBL2318049 (2)
1 / 2
P23280 Carbonic anhydrase 6 Lyase CHEMBL925 CHEMBL887925 (1) CHEMBL1067710 (1)
0 / 0
P05164 Myeloperoxidase Enzyme CHEMBL925 CHEMBL2352940 (1)
1 / 2
Q9ULX7 Carbonic anhydrase 14 Lyase CHEMBL925 CHEMBL889441 (1)
0 / 0
O43570 Carbonic anhydrase 12 Lyase CHEMBL925 CHEMBL932484 (1)
1 / 2
P00915 Carbonic anhydrase 1 Lyase CHEMBL925 CHEMBL1076637 CHEMBL889435 (1) CHEMBL885801 (1)
CHEMBL887923 (1) CHEMBL932481 (1)
CHEMBL970750 (1) CHEMBL965607 (1)
CHEMBL965608 (1) CHEMBL1067708 (1)
CHEMBL2156560 (2) CHEMBL2318048 (2)
0 / 0
Q16790 Carbonic anhydrase 9 Lyase CHEMBL925 CHEMBL932483 (1)
0 / 1
P07451 Carbonic anhydrase 3 Lyase CHEMBL925 CHEMBL970752 (1) CHEMBL953319 (1)
0 / 0
P22748 Carbonic anhydrase 4 Lyase CHEMBL925 CHEMBL970753 (1) CHEMBL1008327 (1)
1 / 1
O00255 Menin Unclassified protein CHEMBL1076637 CHEMBL1614531 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL1076637 CHEMBL1614531 (1)
1 / 3
Q05BR4 SLC16A10 protein Unclassified protein CHEMBL925 CHEMBL2076232 (1) CHEMBL2076248 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#143860 Hyperchlorhidrosis, isolated O43570
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#254600 Myeloperoxidase deficiency; mpod P05164
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#600852 Retinitis pigmentosa 17; rp17 P22748
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798

KEGG DISEASE (14)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00101 Other phagocyte defects P05164 (related)
H00003 Acute myeloid leukemia (AML) P05164 (marker)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)