PCIDB

KNApSAcK Metabolite C00019491

Metabolite

KNApSAcK Entry

id C00019491
Name Euscophic acid / Jacarandic acid / 2alpha,3alpha,19alpha-Trihydroxyurs-12-en-28-oic acid
CAS RN 53155-25-2
Standard InChI InChI=1S/C30H48O5/c1-17-10-13-30(24(33)34)15-14-27(5)18(22(30)29(17,7)35)8-9-21-26(4)16-19(31)23(32)25(2,3)20(26)11-12-28(21,27)6/h8,17,19-23,31-32,35H,9-16H2,1-7H3,(H,33,34)/t17-,19-,20+,21-,22-,23-,26+,27-,28-,29-,30+/m1/s1
Standard InChI (Main Layer) InChI=1S/C30H48O5/c1-17-10-13-30(24(33)34)15-14-27(5)18(22(30)29(17,7)35)8-9-21-26(4)16-19(31)23(32)25(2,3)20(26)11-12-28(21,27)6/h8,17,19-23,31-32,35H,9-16H2,1-7H3,(H,33,34)

Cluster

Phytochemical cluster No. 51
KCF-S cluster No. 13

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL223484 CHEMBL239077 CHEMBL1270647

KEGG

By LinkDB C17890

CTD

By CAS RN C007695

Human Protein / Gene in interaction

2 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P28845 Corticosteroid 11-beta-dehydrogenase isozyme 1 Enzyme CHEMBL239077 CHEMBL1072762 (1)
1 / 1
P80365 Corticosteroid 11-beta-dehydrogenase isozyme 2 Enzyme CHEMBL239077 CHEMBL1072765 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#218030 Apparent mineralocorticoid excess; ame P80365
#604931 Cortisone reductase deficiency 1; cortrd1 P28845

KEGG DISEASE (2)

KEGG disease name UniProt
H01111 Cortisone reductase deficiency (CRD) P28845 (related)
H00259 Apparent mineralocorticoid excess syndrome P80365 (related)