Species

KNApSAcK Entry

Organism name Cotoneaster simonsii
Genus Cotoneaster
Family Rosaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Cotoneaster
Linked NCBI taxonomy ID 36607
Linked level genus

Family

Family in NCBI taxonomy Rosaceae
ID 3745

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00010118 External link 512 Trifoside
/ Prunetrin
/ Prunitrin
/ Prunitroside
/ Prunetin 4'-O-glucoside
CHEMBL1568702
6 / 5 / 3 No. 2 No. 15
C00013810 External link 512 Kaempferol 7-methyl ether 4'-glucoside
/ 2-[4-(beta-D-Glucopyranosyloxy)phenyl]-3,5-dihydroxy-7-methoxy-4H-1-benzopyran-4-one
No. 2 No. 15
C00009452 External link 512 Isoprunetin
/ 5-O-Methylgenistein
CHEMBL1479463
6 / 0 / 0 No. 3 No. 15
C00019490 External link 512 Tormentic acid
/ 2alpha,3beta,19alpha-Trihydroxyurs-12-en-28-oic acid
CHEMBL223484
CHEMBL239077
CHEMBL1270647
2 / 2 / 2 No. 13 No. 51
C00003558 External link 512 Ursolic acid
CHEMBL297810
CHEMBL56048
CHEMBL300594
CHEMBL169
CHEMBL176234
CHEMBL491715
CHEMBL1316667
CHEMBL1555307
CHEMBL1593360
CHEMBL1979720
C005466
47 / 26 / 33 15 / 12 No. 13 No. 51
C00019491 External link 512 Euscophic acid
/ Jacarandic acid
/ 2alpha,3alpha,19alpha-Trihydroxyurs-12-en-28-oic acid
CHEMBL223484
CHEMBL239077
CHEMBL1270647
C007695
2 / 2 / 2 No. 13 No. 51
C00002638 External link 512 Arbutin
CHEMBL226495
CHEMBL232202
CHEMBL1357990
D001104
5 / 7 / 5 282 / 0 No. 45 No. 72
C00002724 External link 512 Heriguard
/ Chlorogenic acid
/ 3-O-Caffeoylquinic acid
CHEMBL284616
CHEMBL230481
CHEMBL249450
CHEMBL1332980
CHEMBL1394423
CHEMBL1419611
CHEMBL1473644
CHEMBL1552319
D002726
30 / 19 / 22 37 / 9 No. 314 No. 6

Human Protein / Gene in interactions

75 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002638 C00002724 C00003558 0 / 0
P28845 Corticosteroid 11-beta-dehydrogenase isozyme 1 Enzyme C00003558 C00019490 C00019491 1 / 1
P80365 Corticosteroid 11-beta-dehydrogenase isozyme 2 Enzyme C00003558 C00019490 C00019491 1 / 1
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00002638 C00002724 C00003558 0 / 3
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00002724 C00003558 0 / 0
O60218 Aldo-keto reductase family 1 member B10 Enzyme C00002724 C00003558 0 / 0
P06746 DNA polymerase beta Enzyme C00003558 C00009452 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002724 C00010118 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00002638 C00003558 1 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002724 C00009452 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00009452 C00010118 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002724 C00003558 0 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002724 C00003558 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00009452 C00010118 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002724 C00003558 0 / 0
P15121 Aldose reductase Enzyme C00002724 C00003558 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002724 C00003558 0 / 1
O75496 Geminin Unclassified protein C00002724 C00009452 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002724 C00003558 1 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002724 0 / 0
Q9UQL6 Histone deacetylase 5 Hydrolase C00003558 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00003558 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00002638 2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00003558 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00010118 0 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme C00002724 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00010118 4 / 2
P10586 Receptor-type tyrosine-protein phosphatase F Receptor tyrosine-protein phosphatase C00003558 0 / 0
P10145 Interleukin-8 Secreted protein C00002724 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00003558 0 / 0
P40763 Signal transducer and activator of transcription 3 Transcription Factor C00002724 1 / 2
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00009452 0 / 0
Q04206 Transcription factor p65 Transcription Factor C00003558 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00003558 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00003558 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00002724 0 / 1
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00003558 2 / 2
P14679 Tyrosinase Oxidoreductase C00002638 4 / 2
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00002724 0 / 0
Q96RI1 Bile acid receptor NR1H4 C00003558 0 / 0
O15379 Histone deacetylase 3 Hydrolase C00003558 0 / 0
P18433 Receptor-type tyrosine-protein phosphatase alpha Receptor tyrosine-protein phosphatase C00003558 0 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00003558 3 / 1
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00002724 3 / 3
P51692 Signal transducer and activator of transcription 5B Unclassified protein C00002724 1 / 1
O15118 Niemann-Pick C1 protein Unclassified protein C00010118 1 / 1
P16473 Thyrotropin receptor Glycohormone receptor C00002724 3 / 2
P56524 Histone deacetylase 4 Hydrolase C00003558 1 / 1
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00003558 0 / 0
P30305 M-phase inducer phosphatase 2 Ser_Thr_Tyr C00003558 0 / 0
P08047 Transcription factor Sp1 Unclassified protein C00003558 0 / 0
P02545 Prelamin-A/C Unclassified protein C00003558 11 / 10
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00003558 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00002724 0 / 0
Q8TDU6 G-protein coupled bile acid receptor 1 Steroid-like ligand receptor C00003558 0 / 0
P24666 Low molecular weight phosphotyrosine protein phosphatase Tyr C00003558 0 / 0
Q13547 Histone deacetylase 1 Hydrolase C00003558 0 / 0
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00003558 0 / 0
P06239 Tyrosine-protein kinase Lck Src C00002724 0 / 1
P17706 Tyrosine-protein phosphatase non-receptor type 2 Tyr C00003558 0 / 1
Q9UBN7 Histone deacetylase 6 Hydrolase C00003558 0 / 0
P29350 Tyrosine-protein phosphatase non-receptor type 6 Tyr C00003558 0 / 0
Q13093 Platelet-activating factor acetylhydrolase Enzyme C00002724 3 / 0
P23469 Receptor-type tyrosine-protein phosphatase epsilon Receptor tyrosine-protein phosphatase C00003558 0 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00002724 2 / 2
P46063 ATP-dependent DNA helicase Q1 Enzyme C00003558 0 / 0
P42224 Signal transducer and activator of transcription 1-alpha/beta Unclassified protein C00002724 3 / 3
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00002724 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00002724 1 / 1
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00003558 0 / 0
O00255 Menin Unclassified protein C00003558 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00003558 1 / 2
Q13951 Core-binding factor subunit beta Unclassified protein C00003558 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00003558 1 / 4
P19224 UDP-glucuronosyltransferase 1-6 Enzyme C00002724 0 / 0

333 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00002638 C00003558
7592 ZNF41, MRX89 zinc finger protein 41 C00002638
581 BAX, BCL2L4 BCL2-associated X protein C00003558
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00003558
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00003558
9131 AIFM1, AIF, CMTX4, COWCK, COXPD6, PDCD8 apoptosis-inducing factor, mitochondrion-associated, 1 C00003558
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00003558
1557 CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19 cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00003558
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00003558
4313 MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) C00003558
4318 MMP9, CLG4B, GELB, MANDP2, MMP-9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) C00003558
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00003558
7040 TGFB1, CED, DPD1, LAP, TGFB, TGFbeta transforming growth factor, beta 1 C00003558
7150 TOP1, TOPI topoisomerase (DNA) I (EC:5.99.1.2) C00003558
7153 TOP2A, TOP2, TP2A topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) C00003558
10349 ABCA10, EST698739 ATP-binding cassette, sub-family A (ABC1), member 10 C00002638
154664 ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 C00002638
150000 ABCC13, C21orf73, PRED6 ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene C00002638
130013 ACMSD aminocarboxymuconate semialdehyde decarboxylase (EC:4.1.1.45) C00002638
94 ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I activin A receptor type II-like 1 (EC:2.7.11.30) C00002638
8728 ADAM19, MADDAM, MLTNB ADAM metallopeptidase domain 19 C00002638
8748 ADAM20 ADAM metallopeptidase domain 20 C00002638
8756 ADAM7, ADAM_7, ADAM-7, EAPI, GP-83, GP83 ADAM metallopeptidase domain 7 C00002638
9508 ADAMTS3, ADAMTS-4 ADAM metallopeptidase with thrombospondin type 1 motif, 3 (EC:3.4.24.-) C00002638
56999 ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 C00002638
155 ADRB3, BETA3AR adrenoceptor beta 3 C00002638
121536 AEBP2 AE binding protein 2 C00002638
60312 AFAP1, AFAP, AFAP-110, AFAP110 actin filament associated protein 1 C00002638
84871 AGBL4, CCP6 ATP/GTP binding protein-like 4 C00002638
56894 AGPAT3, LPAAT-GAMMA1, LPAAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 (EC:2.3.1.51) C00002638
79026 AHNAK, AHNAKRS AHNAK nucleoprotein C00002638
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00002638
401138 AMTN, UNQ689 amelotin C00002638
26057 ANKRD17, GTAR, NY-BR-16 ankyrin repeat domain 17 C00002638
200539 ANKRD23, DARP, MARP3 ankyrin repeat domain 23 C00002638
1174 AP1S1, AP19, CLAPS1, MEDNIK, SIGMA1A, WUGSC:H_DJ0747G18.2 adaptor-related protein complex 1, sigma 1 subunit C00002638
55937 APOM, G3a, HSPC336, NG20, apo-M apolipoprotein M C00002638
54840 APTX, AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT aprataxin C00002638
23647 ARFIP2, POR1 ADP-ribosylation factor interacting protein 2 C00002638
9181 ARHGEF2, GEF, GEF-H1, GEFH1, LFP40, P40 Rho/Rac guanine nucleotide exchange factor (GEF) 2 C00002638
402 ARL2, ARFL2 ADP-ribosylation factor-like 2 C00002638
23204 ARL6IP1, AIP1, ARL6IP, ARMER ADP-ribosylation factor-like 6 interacting protein 1 C00002638
170302 ARX, CT121, EIEE1, ISSX, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS aristaless related homeobox C00002638
55616 ASAP3, ACAP4, CENTB6, DDEFL1, UPLC1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 C00002638
439 ASNA1, ARSA-I, ARSA1, ASNA-I, GET3, TRC40, hASNA-I arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) (EC:3.6.3.16) C00002638
83858 ATAD3B, AAA-TOB3, TOB3 ATPase family, AAA domain containing 3B C00002638
1388 ATF6B, CREB-RP, CREBL1, G13 activating transcription factor 6 beta C00002638
338707 B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 (EC:2.4.1.244) C00002638
9529 BAG5, BAG-5 BCL2-associated athanogene 5 C00002638
10286 BCAS2, DAM1, SPF27, Snt309 breast carcinoma amplified sequence 2 C00002638
10295 BCKDK, BCKDKD, BDK branched chain ketoacid dehydrogenase kinase (EC:2.7.11.4) C00002638
658 BMPR1B, ALK-6, ALK6, CDw293 bone morphogenetic protein receptor, type IB (EC:2.7.11.30) C00002638
663 BNIP2, BNIP-2, NIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 C00002638
84446 BRSK1, hSAD1 BR serine/threonine kinase 1 (EC:2.7.11.1 2.7.11.26) C00002638
684 BST2, CD317, TETHERIN bone marrow stromal cell antigen 2 C00002638
11120 BTN2A1, BK14H9.1, BT2.1, BTF1, DJ3E1.1 butyrophilin, subfamily 2, member A1 C00002638
9256 BZRAP1, PBR-IP, PRAX-1, PRAX1, RIM-BP1, RIMBP1 benzodiazapine receptor (peripheral) associated protein 1 C00002638
161502 C15orf26 chromosome 15 open reading frame 26 C00002638
84529 C15orf41, HH114 chromosome 15 open reading frame 41 C00002638
64073 C19orf33, H2RSP, IMUP, IMUP-1, IMUP-2 chromosome 19 open reading frame 33 C00002638
84808 C1orf170, RP11-54O7.8 chromosome 1 open reading frame 170 C00002638
10485 C1orf61, CROC4 chromosome 1 open reading frame 61 C00002638
127795 C1orf87 chromosome 1 open reading frame 87 C00002638
713 C1QB complement component 1, q subcomponent, B chain C00002638
59284 CACNG7 calcium channel, voltage-dependent, gamma subunit 7 C00002638
84290 CAPNS2 calpain, small subunit 2 C00002638
23466 CBX6 chromobox homolog 6 C00002638
55749 CCAR1, RP11-437A18.1 cell division cycle and apoptosis regulator 1 C00002638
80129 CCDC170, C6orf97, bA282P11.1 coiled-coil domain containing 170 C00002638
79140 CCDC28B, RP4-622L5.5 coiled-coil domain containing 28B C00002638
151195 CCNYL1 cyclin Y-like 1 C00002638
10694 CCT8, C21orf112, Cctq, D21S246, PRED71 chaperonin containing TCP1, subunit 8 (theta) C00002638
977 CD151, GP27, MER2, PETA-3, RAPH, SFA1, TSPAN24 CD151 molecule (Raph blood group) C00002638
11126 CD160, BY55, NK1, NK28 CD160 molecule C00002638
283316 CD163L1, CD163B, M160 CD163 molecule-like 1 C00002638
10421 CD2BP2, FWP010, LIN1, PPP1R59, Snu40, U5-52K CD2 (cytoplasmic tail) binding protein 2 C00002638
917 CD3G, CD3-GAMMA, T3G CD3g molecule, gamma (CD3-TCR complex) C00002638
5127 CDK16, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1 cyclin-dependent kinase 16 (EC:2.7.11.22) C00002638
634 CEACAM1, BGP, BGP1, BGPI carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) C00002638
170482 CLEC4C, BDCA2, CD303, CLECSF11, CLECSF7, DLEC, HECL, PRO34150 C-type lectin domain family 4, member C C00002638
22866 CNKSR2, CNK2, KSR2, MAGUIN connector enhancer of kinase suppressor of Ras 2 C00002638
1308 COL17A1, BA16H23.2, BP180, BPA-2, BPAG2, LAD-1 collagen, type XVII, alpha 1 C00002638
1360 CPB1, CPB, PASP, PCPB carboxypeptidase B1 (tissue) (EC:3.4.17.2) C00002638
1363 CPE carboxypeptidase E (EC:3.4.17.10) C00002638
57699 CPNE5, COPN5, CPN5 copine V C00002638
113612 CYP2U1, P450TEC, SPG49, SPG56 cytochrome P450, family 2, subfamily U, polypeptide 1 (EC:1.14.14.1) C00002638
326709 C00002638
9879 DDX46, PRPF5, Prp5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 (EC:3.6.4.13) C00002638
1730 DIAPH2, DIA, DIA2, DRF2, POF, POF2 diaphanous-related formin 2 C00002638
22839 DLGAP4, DAP4, DLP4, RP5-977B1.6, SAPAP4 discs, large (Drosophila) homolog-associated protein 4 C00002638
1745 DLX1 distal-less homeobox 1 C00002638
1657 DMXL1 Dmx-like 1 C00002638
56171 DNAH7 dynein, axonemal, heavy chain 7 C00002638
4189 DNAJB9, ERdj4, MDG-1, MDG1, MST049, MSTP049 DnaJ (Hsp40) homolog, subfamily B, member 9 C00002638
29952 DPP7, DPP2, DPPII, QPP dipeptidyl-peptidase 7 (EC:3.4.14.2) C00002638
1808 DPYSL2, CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2 dihydropyrimidinase-like 2 C00002638
1889 ECE1, ECE endothelin converting enzyme 1 (EC:3.4.24.71) C00002638
80820 EEPD1, HSPC107 endonuclease/exonuclease/phosphatase family domain containing 1 C00002638
80258 EFHC2, dJ1158H2.1 EF-hand domain (C-terminal) containing 2 C00002638
1944 EFNA3, EFL2, EPLG3, Ehk1-L, LERK3 ephrin-A3 C00002638
10278 EFS, CAS3, CASS3, EFS1, EFS2, HEFS, SIN embryonal Fyn-associated substrate C00002638
79631 EFTUD1, FAM42A, HsT19294, RIA1 elongation factor Tu GTP binding domain containing 1 C00002638
23741 EID1, C15orf3, CRI1, EID-1, IRO45620, PTD014, RBP21 EP300 interacting inhibitor of differentiation 1 C00002638
1991 ELANE, ELA2, GE, HLE, HNE, NE, PMN-E, SCN1 elastase, neutrophil expressed (EC:3.4.21.37) C00002638
2018 EMX2 empty spiracles homeobox 2 C00002638
5167 ENPP1, ARHR2, M6S1, NPP1, NPPS, PC-1, PCA1, PDNP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 (EC:3.1.4.1 3.6.1.9) C00002638
2059 EPS8 epidermal growth factor receptor pathway substrate 8 C00002638
8288 EPX, EPO, EPP, EPX-PEN eosinophil peroxidase (EC:1.11.1.7) C00002638
23085 ERC1, Cast2, ELKS, RAB6IP2 ELKS/RAB6-interacting/CAST family member 1 C00002638
711 ERC2-IT1, C1orf1, C3orf51, Po42 ERC2 intronic transcript 1 (non-protein coding) C00002638
2124 EVI2B, CD361, D17S376, EVDB ecotropic viral integration site 2B C00002638
161829 EXD1, EXDL1 exonuclease 3'-5' domain containing 1 C00002638
2165 F13B, FXIIIB coagulation factor XIII, B polypeptide (EC:2.3.2.13) C00002638
131177 FAM3D, EF7, OIT1 family with sequence similarity 3, member D C00002638
51571 FAM49B, L1 family with sequence similarity 49, member B C00002638
115795 FANCD2OS, C3orf24 FANCD2 opposite strand C00002638
356 FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 Fas ligand (TNF superfamily, member 6) C00002638
80204 FBXO11, FBX11, PRMT9, UBR6, VIT1 F-box protein 11 C00002638
157574 FBXO16, FBX16 F-box protein 16 C00002638
2250 FGF5, HBGF-5, Smag-82 fibroblast growth factor 5 C00002638
2261 FGFR3, ACH, CD333, CEK2, HSFGFR3EX, JTK4 fibroblast growth factor receptor 3 (EC:2.7.10.1) C00002638
91010 FMNL3, FHOD3, WBP-3, WBP3 formin-like 3 C00002638
8790 FPGT, GFPP fucose-1-phosphate guanylyltransferase (EC:2.7.7.30) C00002638
80144 FRAS1 Fraser syndrome 1 C00002638
9758 FRMPD4, PDZD10, PDZK10 FERM and PDZ domain containing 4 C00002638
2581 GALC galactosylceramidase (EC:3.2.1.46) C00002638
64762 GAREM, C18orf11, FAM59A, Gm944 GRB2 associated, regulator of MAPK1 C00002638
10755 GIPC1, C19orf3, GIPC, GLUT1CBP, Hs.6454, IIP-1, NIP, RGS19IP1, SEMCAP, SYNECTIIN, SYNECTIN, TIP-2 GIPC PDZ domain containing family, member 1 C00002638
83468 GLT8D2 glycosyltransferase 8 domain containing 2 C00002638
2766 GMPR, GMPR1 guanosine monophosphate reductase (EC:1.7.1.7) C00002638
29889 GNL2, HUMAUANTIG, NGP1, Ngp-1 guanine nucleotide binding protein-like 2 (nucleolar) C00002638
2719 GPC3, DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 glypican 3 C00002638
2820 GPD2, GDH2, GPDM, mGPDH glycerol-3-phosphate dehydrogenase 2 (mitochondrial) (EC:1.1.5.3) C00002638
151556 GPR155, DEP.7, DEPDC3, PGR22 G protein-coupled receptor 155 C00002638
2849 GPR26 G protein-coupled receptor 26 C00002638
2854 GPR32, RVDR1 G protein-coupled receptor 32 C00002638
9290 GPR55 G protein-coupled receptor 55 C00002638
55507 GPRC5D G protein-coupled receptor, family C, group 5, member D C00002638
284110 GSDMA, GSDM, GSDM1 gasdermin A C00002638
2977 GUCY1A2, GC-SA2, GUC1A2 guanylate cyclase 1, soluble, alpha 2 (EC:4.6.1.2) C00002638
9421 HAND1, Hxt, Thing1, bHLHa27, eHand heart and neural crest derivatives expressed 1 C00002638
3024 HIST1H1A, H1.1, H1A, H1F1, HIST1 histone cluster 1, H1a C00002638
8334 HIST1H2AC, H2A/l, H2AFL, dJ221C16.4 histone cluster 1, H2ac C00002638
3131 HLF hepatic leukemia factor C00002638
3218 HOXB8, HOX2, HOX2D, Hox-2.4 homeobox B8 C00002638
84343 HPS3, SUTAL Hermansky-Pudlak syndrome 3 C00002638
3283 HSD3B1, 3BETAHSD, HSD3B, HSDB3, HSDB3A, I, SDR11E1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (EC:1.1.1.145 5.3.3.1) C00002638
27336 HTATSF1, TAT-SF1, TATSF1, dJ196E23.2 HIV-1 Tat specific factor 1 C00002638
3437 IFIT3, CIG-49, GARG-49, IFI60, IFIT4, IRG2, ISG60, P60, RIG-G interferon-induced protein with tetratricopeptide repeats 3 C00002638
9543 IGDCC3, HsT18880, PUNC immunoglobulin superfamily, DCC subclass, member 3 C00002638
51561 IL23A, IL-23, IL-23A, IL23P19, P19, SGRF interleukin 23, alpha subunit p19 C00002638
3563 IL3RA, CD123, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra interleukin 3 receptor, alpha (low affinity) C00002638
3572 IL6ST, CD130, CDW130, GP130, IL-6RB interleukin 6 signal transducer (gp130, oncostatin M receptor) C00002638
9118 INA, NEF5, NF-66, TXBP-1 internexin neuronal intermediate filament protein, alpha C00002638
8821 INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa (EC:3.1.3.66) C00002638
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00002638
9196 KCNAB3, AKR6A9, KCNA3.1B, KCNA3B, KV-BETA-3 potassium voltage-gated channel, shaker-related subfamily, beta member 3 C00002638
79734 KCTD17 potassium channel tetramerization domain containing 17 C00002638
79070 KDELC1, EP58, KDEL1 KDEL (Lys-Asp-Glu-Leu) containing 1 C00002638
55083 KIF26B kinesin family member 26B C00002638
90293 KLHL13, BKLHD2, KIAA1309 kelch-like family member 13 C00002638
8302 KLRC4, NKG2-F, NKG2F killer cell lectin-like receptor subfamily C, member 4 C00002638
197021 LCTL, KLG, KLPH lactase-like C00002638
56891 LGALS14, CLC2, PPL13 lectin, galactoside-binding, soluble, 14 C00002638
79166 LILRP2, CD85m, ILT10, LILRA5 leukocyte immunoglobulin-like receptor pseudogene 2 C00002638
4041 LRP5, BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2 low density lipoprotein receptor-related protein 5 C00002638
4040 LRP6, ADCAD2 low density lipoprotein receptor-related protein 6 C00002638
64101 LRRC4, NGL-2 leucine rich repeat containing 4 C00002638
80059 LRRTM4 leucine rich repeat transmembrane neuronal 4 C00002638
7975 MAFK, NFE2U, P18 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K C00002638
11183 MAP4K5, GCKR, KHS, KHS1, MAPKKKK5 mitogen-activated protein kinase kinase kinase kinase 5 (EC:2.7.11.1) C00002638
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC:2.7.11.24) C00002638
84515 MCM8, C20orf154, dJ967N21.5 minichromosome maintenance complex component 8 (EC:3.6.4.12) C00002638
4188 MDFI, I-MF, I-mfa MyoD family inhibitor C00002638
4239 MFAP4 microfibrillar-associated protein 4 C00002638
90007 MIDN midnolin C00002638
4288 MKI67, KIA, MIB-1 marker of proliferation Ki-67 C00002638
93380 MMGT1, EMC5, TMEM32 membrane magnesium transporter 1 C00002638
245802 MS4A6E membrane-spanning 4-domains, subfamily A, member 6E C00002638
25902 MTHFD1L, FTHFSDC1, MTC1THFS, dJ292B18.2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (EC:6.3.4.3) C00002638
4597 MVD, FP17780, MPD mevalonate (diphospho) decarboxylase (EC:4.1.1.33) C00002638
140469 MYO3B myosin IIIB (EC:2.7.11.1) C00002638
83988 NCALD neurocalcin delta C00002638
257194 NEGR1, DMML2433, IGLON4, KILON, Ntra neuronal growth regulator 1 C00002638
129807 NEU4 sialidase 4 (EC:3.2.1.18) C00002638
85407 NKD1, Naked1 naked cuticle homolog 1 (Drosophila) C00002638
9111 NMI N-myc (and STAT) interactor C00002638
122945 NOXRED1, C14orf148 NADP-dependent oxidoreductase domain containing 1 C00002638
7025 NR2F1, COUP-TFI, EAR-3, EAR3, ERBAL3, NR2F2, SVP44, TCFCOUP1, TFCOUP1 nuclear receptor subfamily 2, group F, member 1 C00002638
8828 NRP2, NP2, NPN2, PRO2714, VEGF165R2 neuropilin 2 C00002638
4909 NTF4, GLC10, GLC1O, NT-4, NT-4/5, NT-5, NT4, NT5, NTF5 neurotrophin 4 C00002638
283298 OLFML1, UNQ564 olfactomedin-like 1 C00002638
23762 OSBP2, HLM, ORP-4, ORP4, OSBPL1, OSBPL4 oxysterol binding protein 2 C00002638
114885 OSBPL11, ORP-11, ORP11, OSBP12, TCCCIA00292 oxysterol binding protein-like 11 C00002638
5013 OTX1 orthodenticle homeobox 1 C00002638
11252 PACSIN2, SDPII protein kinase C and casein kinase substrate in neurons 2 C00002638
8505 PARG, PARG99 poly (ADP-ribose) glycohydrolase (EC:3.2.1.143) C00002638
84108 PCGF6, MBLR, RNF134 polycomb group ring finger 6 C00002638
55251 PCMTD2, C20orf36 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 C00002638
80003 PCNXL2 pecanex-like 2 (Drosophila) C00002638
5174 PDZK1, CAP70, CLAMP, NHERF-3, NHERF3, PDZD1 PDZ domain containing 1 C00002638
5196 PF4, CXCL4, PF-4, SCYB4 platelet factor 4 C00002638
55276 PGM2 phosphoglucomutase 2 (EC:5.4.2.2 5.4.2.7) C00002638
9091 PIGQ, GPI1, c407A10.1 phosphatidylinositol glycan anchor biosynthesis, class Q (EC:2.4.1.198) C00002638
5300 PIN1, DOD, UBL5 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 (EC:5.2.1.8) C00002638
23760 PITPNB, PI-TP-beta, PtdInsTP, VIB1B phosphatidylinositol transfer protein, beta C00002638
5314 PKHD1, ARPKD, FCYT, TIGM1 polycystic kidney and hepatic disease 1 (autosomal recessive) C00002638
5427 POLE2, DPE2 polymerase (DNA directed), epsilon 2, accessory subunit (EC:2.7.7.7) C00002638
51535 PPHLN1, HSPC232 periphilin 1 C00002638
5553 PRG2, BMPG, MBP, MBP1 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) C00002638
5613 PRKX, PKX1 protein kinase, X-linked (EC:2.7.11.1) C00002638
3275 PRMT2, HRMT1L1 protein arginine methyltransferase 2 (EC:2.1.1.125) C00002638
285800 PRR18 proline rich 18 C00002638
5396 PRRX1, AGOTC, PHOX1, PMX1, PRX-1, PRX1 paired related homeobox 1 C00002638
5645 PRSS2, TRY2, TRY8, TRYP2 protease, serine, 2 (trypsin 2) (EC:3.4.21.4) C00002638
5719 PSMD13, HSPC027, Rpn9, S11, p40.5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 C00002638
5709 PSMD3, P58, RPN3, S3, TSTA2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 C00002638
22930 RAB3GAP1, P130, RAB3GAP, RAB3GAP130, WARBM1 RAB3 GTPase activating protein subunit 1 (catalytic) C00002638
51560 RAB6B RAB6B, member RAS oncogene family C00002638
153020 RASGEF1B, GPIG4 RasGEF domain family, member 1B C00002638
10739 RFPL2, RNF79 ret finger protein-like 2 C00002638
10738 RFPL3 ret finger protein-like 3 C00002638
727800 RNF208 ring finger protein 208 C00002638
6197 RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2 ribosomal protein S6 kinase, 90kDa, polypeptide 3 (EC:2.7.11.1) C00002638
54665 RSBN1, ROSBIN, RP11-324J2.1 round spermatid basic protein 1 C00002638
6291 SAA4, C-SAA, CSAA serum amyloid A4, constitutive C00002638
51097 SCCPDH, NET11, RP11-439E19.2 saccharopine dehydrogenase (putative) (EC:1.5.1.9) C00002638
6324 SCN1B, ATFB13, BRGDA5, GEFSP1 sodium channel, voltage-gated, type I, beta subunit C00002638
6385 SDC4, SYND4 syndecan 4 C00002638
6406 SEMG1, CT103, SEMG, SGI, dJ172H20.2 semenogelin I C00002638
5104 SERPINA5, PAI-3, PAI3, PCI, PCI-B, PLANH3, PROCI serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 C00002638
3053 SERPIND1, D22S673, HC2, HCF2, HCII, HLS2, LS2, THPH10 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 C00002638
23451 SF3B1, Hsh155, MDS, PRP10, PRPF10, SAP155, SF3b155 splicing factor 3b, subunit 1, 155kDa C00002638
6425 SFRP5, SARP3 secreted frizzled-related protein 5 C00002638
118980 SFXN2 sideroflexin 2 C00002638
6456 SH3GL2, CNSA2, EEN-B1, SH3D2A, SH3P4 SH3-domain GRB2-like 2 C00002638
23309 SIN3B SIN3 transcription regulator family member B C00002638
9058 SLC13A2, NADC1, NaCT, NaDC-1, SDCT1 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 C00002638
51296 SLC15A3, OCTP, PHT2, PTR3 solute carrier family 15 (oligopeptide transporter), member 3 C00002638
6571 SLC18A2, SVAT, SVMT, VAT2, VMAT2 solute carrier family 18 (vesicular monoamine transporter), member 2 C00002638
151295 SLC23A3, E2BP3, SVCT3, Yspl1 solute carrier family 23, member 3 C00002638
83884 SLC25A2, ORC2, ORNT2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 C00002638
10999 SLC27A4, ACSVL4, FATP4, IPS solute carrier family 27 (fatty acid transporter), member 4 (EC:6.2.1.-) C00002638
84889 SLC7A3, ATRC3, CAT-3, CAT3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 C00002638
81796 SLCO5A1, OATP-J, OATP-RP4, OATP5A1, OATPRP4, SLC21A15 solute carrier organic anion transporter family, member 5A1 C00002638
79753 SNIP1, PMRED Smad nuclear interacting protein 1 C00002638
122809 SOCS4, SOCS7 suppressor of cytokine signaling 4 C00002638
221178 SPATA13, ARHGEF29, ASEF2 spermatogenesis associated 13 C00002638
64847 SPATA20, SSP411, Tisp78 spermatogenesis associated 20 C00002638
10558 SPTLC1, HSAN1, HSN1, LBC1, LCB1, SPT1, SPTI serine palmitoyltransferase, long chain base subunit 1 (EC:2.3.1.50) C00002638
9754 STARD8, ARHGAP38, DLC3, STARTGAP3 StAR-related lipid transfer (START) domain containing 8 C00002638
85360 SYDE1, 7h3 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) C00002638
8189 SYMPK, SPK, SYM symplekin C00002638
6886 TAL1, SCL, TCL5, bHLHa17, tal-1 T-cell acute lymphocytic leukemia 1 C00002638
23435 TARDBP, ALS10, TDP-43 TAR DNA binding protein C00002638
6938 TCF12, CRS3, HEB, HTF4, HsT17266, bHLHb20 transcription factor 12 C00002638
6947 TCN1, TC-1, TC1, TCI transcobalamin I (vitamin B12 binding protein, R binder family) C00002638
26136 TES, TESS, TESS-2 testis derived transcript (3 LIM domains) C00002638
56156 TEX13B, TGC3B, TSGA5 testis expressed 13B C00002638
7043 TGFB3, ARVD, ARVD1, TGF-beta3 transforming growth factor, beta 3 C00002638
7092 TLL1, ASD6, TLL tolloid-like 1 (EC:3.4.24.-) C00002638
25789 TMEM59L, BSMAP, C19orf4 transmembrane protein 59-like C00002638
54863 TOR4A, C9orf167 torsin family 4, member A C00002638
9697 TRAM2 translocation associated membrane protein 2 C00002638
11181 TREH, TRE, TREA trehalase (brush-border membrane glycoprotein) (EC:3.2.1.28) C00002638
7248 TSC1, LAM, TSC tuberous sclerosis 1 C00002638
9819 TSC22D2, TILZ4a, TILZ4b, TILZ4c TSC22 domain family, member 2 C00002638
128553 TSHZ2, C20orf17, OVC10-2, TSH2, ZABC2, ZNF218 teashirt zinc finger homeobox 2 C00002638
118491 TTC18 tetratricopeptide repeat domain 18 C00002638
55001 TTC22 tetratricopeptide repeat domain 22 C00002638
7289 TULP3, TUBL3 tubby like protein 3 C00002638
51619 UBE2D4, HBUCE1 ubiquitin-conjugating enzyme E2D 4 (putative) (EC:6.3.2.19) C00002638
9040 UBE2M, UBC-RS2, UBC12, hUbc12 ubiquitin-conjugating enzyme E2M (EC:6.3.2.19) C00002638
29979 UBQLN1, DA41, DSK2, PLIC-1, UBQN, XDRP1 ubiquilin 1 C00002638
84101 USP44 ubiquitin specific peptidase 44 (EC:3.4.19.12) C00002638
51118 UTP11L, CGI94 UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast) C00002638
157680 VPS13B, CHS1, COH1 vacuolar protein sorting 13 homolog B (yeast) C00002638
23339 VPS39, TLP, VAM6, hVam6p vacuolar protein sorting 39 homolog (S. cerevisiae) C00002638
146177 VWA3A von Willebrand factor A domain containing 3A C00002638
126820 WDR63, DIC3, NYD-SP29, RP11-507C22.2 WD repeat domain 63 C00002638
80326 WNT10A, OODD, SSPS, STHAG4 wingless-type MMTV integration site family, member 10A C00002638
9502 XAGE2, CT12.2, GAGED3, XAGE-2 X antigen family, member 2 C00002638
26137 ZBTB20, DPZF, HOF, ODA-8S, ZNF288 zinc finger and BTB domain containing 20 C00002638
51043 ZBTB7B, THPOK, ZBTB15, ZFP-67, ZFP67, ZNF857B, c-KROX, hcKROX zinc finger and BTB domain containing 7B C00002638
51201 ZDHHC2, DHHC2, ZNF372 zinc finger, DHHC-type containing 2 (EC:2.3.1.225) C00002638
55888 ZKSCAN7, ZFP, ZNF167, ZNF448, ZNF64, ZSCAN39 zinc finger with KRAB and SCAN domains 7 C00002638
7700 ZNF141, D4S90, PAPA6, pHZ-44 zinc finger protein 141 C00002638
162967 ZNF320, ZFPL zinc finger protein 320 C00002638
117608 ZNF354B, KID2 zinc finger protein 354B C00002638
578 BAK1, BAK, BAK-LIKE, BCL2L7, CDN1 BCL2-antagonist/killer 1 C00003558
84330 ZNF414, ZFP414 zinc finger protein 414 C00002638
158399 ZNF483, ZKSCAN16, ZSCAN48 zinc finger protein 483 C00002638
162968 ZNF497 zinc finger protein 497 C00002638
93474 ZNF670 zinc finger protein 670 C00002638
347344 ZNF81, HFZ20, MRX45, dJ54B20.6 zinc finger protein 81 C00002638
7783 ZP2, ZPA, Zp-2 zona pellucida glycoprotein 2 (sperm receptor) C00002638
47 ACLY, ACL, ATPCL, CLATP ATP citrate lyase (EC:2.3.3.8) C00002724
358 AQP1, AQP-CHIP, CHIP28, CO aquaporin 1 C00002724
360 AQP3, AQP-3, GIL aquaporin 3 (Gill blood group) C00002724
367 AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM androgen receptor C00002724
960 CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1 CD44 molecule (Indian blood group) C00002724
999 CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO cadherin 1, type 1, E-cadherin (epithelial) C00002724
1277 COL1A1, OI4 collagen, type I, alpha 1 C00002724
4512 COX1, COI, MTCO1, MT-CO1 cytochrome c oxidase subunit I C00002724
114757 CYGB, HGB, STAP cytoglobin C00002724
1830 DSG3, CDHF6, PVA desmoglein 3 C00002724
1950 EGF, HOMG4, URG epidermal growth factor C00002724
2200 FBN1, ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFS1, OCTD, SGS, SSKS, WMS, WMS2 fibrillin 1 C00002724
2201 FBN2, CCA, DA9 fibrillin 2 C00002724
2246 FGF1, AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1, HBGF1 fibroblast growth factor 1 (acidic) C00002724
2896 GRN, CLN11, GEP, GP88, PCDGF, PEPI, PGRN granulin C00002724
3036 HAS1, HAS hyaluronan synthase 1 (EC:2.4.1.212) C00002724
3315 HSPB1, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27 heat shock 27kDa protein 1 C00002724
3552 IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1 interleukin 1, alpha C00002724
3852 KRT5, CK5, DDD, DDD1, EBS2, K5, KRT5A keratin 5 C00002724
4157 MC1R, CMM5, MSH-R, SHEP2 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) C00002724
4846 NOS3, ECNOS, eNOS nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) C00002724
5241 PGR, NR3C3, PR progesterone receptor C00002724
8985 PLOD3, LH3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (EC:1.14.11.4) C00002724
5468 PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma peroxisome proliferator-activated receptor gamma C00002724
5886 RAD23A, HHR23A, HR23A RAD23 homolog A (S. cerevisiae) C00002724
5914 RARA, NR1B1, RAR retinoic acid receptor, alpha C00002724
6256 RXRA, NR2B1 retinoid X receptor, alpha C00002724
6649 SOD3, EC-SOD superoxide dismutase 3, extracellular (EC:1.15.1.1) C00002724
6716 SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (EC:1.3.1.22) C00002724
7178 TPT1, HRF, TCTP, p02, p23 tumor protein, translationally-controlled 1 C00002724
7295 TXN, TRDX, TRX, TRX1 thioredoxin C00002724
7299 TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 tyrosinase (EC:1.14.18.1) C00002724
7306 TYRP1, CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP, b-PROTEIN tyrosinase-related protein 1 (EC:1.14.18.-) C00002724
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00002724
54659 UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) C00002724
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00002724
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00002724

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (54)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#218030 Apparent mineralocorticoid excess; ame P80365
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#600807 Asthma, susceptibility to Q13093
#209950 Atypical mycobacteriosis, familial P42224
#600430 Brachydactyly-mental retardation syndrome; bdmr P56524
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#614162 Candidiasis, familial, 7; candf7 P42224
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#604931 Cortisone reductase deficiency 1; cortrd1 P28845
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#137800 Glioma susceptibility 1; glm1 O75874
#245590 Growth hormone insensitivity with immunodeficiency P51692
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#147060 Hyper-ige recurrent infection syndrome, autosomal dominant P40763
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#147050 Ige responsiveness, atopic; iger Q13093
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613688 Long qt syndrome 2; lqt2 Q12809
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#613796 Mycobacterial and viral infections, susceptibility to, autosomal recessive P42224
#257220 Niemann-pick disease, type c1; npc1 O15118
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093
#275210 Restrictive dermopathy, lethal P02545
#609620 Short qt syndrome 1; sqt1 Q12809
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (53)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
P11511 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00036 Osteosarcoma P08684 (marker)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00794 Aromatase excess syndrome P11511 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00408 Type I diabetes mellitus P17706 (related)
H01111 Cortisone reductase deficiency (CRD) P28845 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00027 Ovarian cancer P38398 (related)
H00031 Breast cancer P38398 (related)
H00016 Oral cancer P40763 (related)
H00107 Other well-defined immunodeficiency syndromes P40763 (related)
H00089 IFN-gamma/IL-12 axis P42224 (related)
H00363 Candidiasis P42224 (related)
H01109 Chronic mucocutaneous candidiasis (CMC) P42224 (related)
H00931 Growth hormone insensitivity with immunodeficiency P51692 (related)
H00561 Brachydacytly-mental retardation syndrome and Smith-Magenis syndrome P56524 (related)
H00259 Apparent mineralocorticoid excess syndrome P80365 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)

Diseases related to CTD interactions

21 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D001284 Atrophy C00003558
D006528 Carcinoma, Hepatocellular C00003558
D002471 Cell Transformation, Neoplastic C00003558
D003921 Diabetes Mellitus, Experimental C00003558
D006943 Hyperglycemia C00003558
D006949 Hyperlipidemias C00003558
D006965 Hyperplasia C00003558
D007249 Inflammation C00003558
D008103 Liver Cirrhosis C00003558
D017202 Myocardial Ischemia C00003558
D009369 Neoplasms C00003558
D012878 Skin Neoplasms C00003558
D000647 Amnesia C00002724
D056486 Drug-Induced Liver Injury C00002724
D006937 Hypercholesterolemia C00002724
D006951 Hyperlipoproteinemias C00002724
D015228 Hypertriglyceridemia C00002724
D052456 Hypoalphalipoproteinemias C00002724
D008545 Melanoma C00002724
D009336 Necrosis C00002724
D015431 Weight Loss C00002724