PCIDB

KNApSAcK Metabolite C00023313

Metabolite

KNApSAcK Entry

id C00023313
Name Allmatrine / 6-Allomatrine / 6beta-Matrine / (+)-Allomatrine / Tetrahydroisosophoramine
CAS RN 641-39-4
Standard InChI InChI=1S/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15+/m0/s1
Standard InChI (Main Layer) InChI=1S/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2

Cluster

Phytochemical cluster No. 3
KCF-S cluster No. 85

Link

ChEMBL

By standard InChI CHEMBL383443
By standard InChI Main Layer CHEMBL204860 CHEMBL383443 CHEMBL525227 CHEMBL1396816 CHEMBL1733145 CHEMBL1824581

KEGG

By LinkDB

CTD

By CAS RN

Human Protein / Gene in interaction

5 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P11387 DNA topoisomerase 1 Isomerase CHEMBL1824581 CHEMBL1826307 (1)
0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme CHEMBL1733145 CHEMBL1738606 (1)
0 / 0
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL1396816 CHEMBL1613808 (1)
0 / 0
O00255 Menin Unclassified protein CHEMBL1396816 CHEMBL1614531 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL1396816 CHEMBL1614531 (1)
1 / 3

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255

KEGG DISEASE (7)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)