PCIDB

KNApSAcK Metabolite C00003780

Metabolite

KNApSAcK Entry

id C00003780
Name Neoxanthin / Folioxanthin
CAS RN 14660-91-4
Standard InChI InChI=1S/C40H56O4/c1-29(17-13-19-31(3)21-22-35-36(5,6)25-33(41)27-38(35,9)43)15-11-12-16-30(2)18-14-20-32(4)23-24-40-37(7,8)26-34(42)28-39(40,10)44-40/h11-21,23-24,33-34,41-43H,25-28H2,1-10H3/b12-11+,17-13+,18-14+,24-23+,29-15+,30-16+,31-19+,32-20+/t22-,33-,34-,38+,39+,40-/m0/s1
Standard InChI (Main Layer) InChI=1S/C40H56O4/c1-29(17-13-19-31(3)21-22-35-36(5,6)25-33(41)27-38(35,9)43)15-11-12-16-30(2)18-14-20-32(4)23-24-40-37(7,8)26-34(42)28-39(40,10)44-40/h11-21,23-24,33-34,41-43H,25-28H2,1-10H3

Cluster

Phytochemical cluster No. 59
KCF-S cluster No. 114

Link

ChEMBL

By standard InChI
By standard InChI Main Layer

KEGG

By LinkDB C08606

CTD

By CAS RN C011947

Human Protein / Gene in interaction

CTD interaction (4)

compound gene gene name gene description interaction interaction type form reference
pmid
C011947 9131 AIFM1
AIF
CMTX4
COWCK
COXPD6
PDCD8
apoptosis-inducing factor, mitochondrion-associated, 1 neoxanthin affects the localization of AIFM1 protein affects localization
protein 17186379
C011947 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) neoxanthin results in increased cleavage of and results in increased activity of CASP3 protein increases activity
/ increases cleavage
protein 17186379
C011947 841 CASP8
ALPS2B
CAP4
Casp-8
FLICE
MACH
MCH5
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) neoxanthin results in increased activity of CASP8 protein increases activity
protein 17186379
C011947 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) neoxanthin results in increased cleavage of and results in increased activity of CASP9 protein increases activity
/ increases cleavage
protein 17186379