PCIDB

KNApSAcK Metabolite C00003794

Metabolite

KNApSAcK Entry

id C00003794
Name Chrysin / 5,7-Dihydroxyflavone / 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one
CAS RN 480-40-0
Standard InChI InChI=1S/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H
Standard InChI (Main Layer) InChI=1S/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 76

Link

ChEMBL

By standard InChI CHEMBL117
By standard InChI Main Layer CHEMBL117

KEGG

By LinkDB C10028

CTD

By CAS RN C043561

Species

Summary

Plant class

class name count
asterids 17
rosids 11
Spermatophyta 2
Magnoliophyta 2
eudicotyledons 1
Euphyllophyta 1
Liliopsida 1

Family (Top 10)

family name count
Asteraceae 5
Fabaceae 5
Lamiaceae 5
Annonaceae 2
Pinaceae 2
Passifloraceae 2
Boraginaceae 1
Cistaceae 1
Hydrophyllaceae 1
Escalloniaceae 1

List (35)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Acacia constricta 138020 Fabaceae rosids Viridiplantae
Acacia neovernicosa 199150 Fabaceae rosids Viridiplantae
Adina cordifolia Roxb. 170034 Rubiaceae asterids Viridiplantae
Anaxagorea luzonensis A.GRAY 235716 Annonaceae Magnoliophyta Viridiplantae
Anomianthus dulcis 174962 Annonaceae Magnoliophyta Viridiplantae
Artemisia campestris ssp. glutinosa 4219 Asteraceae asterids Viridiplantae
Baccharis viminea 41487 Asteraceae asterids Viridiplantae
Centaurea pseudoscabiosa subsp.pseudoscabiosa Boiss.et aBuhse 41503 Asteraceae asterids Viridiplantae
Cheilanthes kaulfussii 1108060 Pteridaceae Euphyllophyta Viridiplantae
Chenopodium graveolens 1072218 Amaranthaceae eudicotyledons Viridiplantae
Cistus populifolius 335177 Cistaceae rosids Viridiplantae
Cypripedium macranthos var. rebunense 332480 Orchidaceae Liliopsida Viridiplantae
Elsholtzia bodinieri 41225 Lamiaceae asterids Viridiplantae
Eriodictyon sessilifolium 79350 Hydrophyllaceae asterids Viridiplantae
Escallonia spp. 23075 Escalloniaceae asterids Viridiplantae
Flourensia resinosa 191157 Asteraceae asterids Viridiplantae
Heliotropium pycnophyllum 244104 Boraginaceae asterids Viridiplantae
Lonicera japonica 105884 Caprifoliaceae asterids Viridiplantae
Malus doumeri varl formosana 3749 Rosaceae rosids Viridiplantae
Mikania hirsutissima 102786 Asteraceae asterids Viridiplantae
Mimulus moschatus 270993 Phrymaceae asterids Viridiplantae
Ononis vaginalis 798051 Fabaceae rosids Viridiplantae
Oxytropis pseudoglandulosa 20802 Fabaceae rosids Viridiplantae
Pajanelia multijuga 24079 Bignoniaceae asterids Viridiplantae
Passiflora caerulea 159428 Passifloraceae rosids Viridiplantae
Passiflora serratodigitata 231192 Passifloraceae rosids Viridiplantae
Pinus spp. 3318 Pinaceae Spermatophyta Viridiplantae
Populus spp. 3689 Salicaceae rosids Viridiplantae
Pseudotsuga wilsoniana 71408 Pinaceae Spermatophyta Viridiplantae
Scutellaria discolor 4139 Lamiaceae asterids Viridiplantae
Scutellaria oreophila 4139 Lamiaceae asterids Viridiplantae
Scutellaria orientalis 53170 Lamiaceae asterids Viridiplantae
Scutellaria strigillosa 4139 Lamiaceae asterids Viridiplantae
Spartium junceum 49843 Fabaceae rosids Viridiplantae
Ulmus sieboldiana 24735 Ulmaceae rosids Viridiplantae

Human Protein / Gene in interaction

100 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 CHEMBL117 CHEMBL1261123 (1) CHEMBL1614110 (1)
CHEMBL1741321 (1)
1 / 0
P14061 Estradiol 17-beta-dehydrogenase 1 Enzyme CHEMBL117 CHEMBL957998 (1) CHEMBL957999 (1)
0 / 0
P33527 Multidrug resistance-associated protein 1 drugs CHEMBL117 CHEMBL2076026 (1) CHEMBL2076036 (1)
0 / 0
P22310 UDP-glucuronosyltransferase 1-4 Enzyme CHEMBL117 CHEMBL1908082 (1)
3 / 0
P04637 Cellular tumor antigen p53 Transcription Factor CHEMBL117 CHEMBL1613992 (1) CHEMBL1613995 (2)
7 / 44
Q16637 Survival motor neuron protein Unclassified protein CHEMBL117 CHEMBL1613842 (3)
4 / 2
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme CHEMBL117 CHEMBL1908087 (1)
0 / 0
Q99700 Ataxin-2 Unclassified protein CHEMBL117 CHEMBL2114784 (1)
1 / 1
P35354 Prostaglandin G/H synthase 2 Oxidoreductase CHEMBL117 CHEMBL1014033 (1)
0 / 3
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 CHEMBL117 CHEMBL1794524 (1) CHEMBL1794552 (1)
CHEMBL2341203 (1) CHEMBL2341207 (1)
0 / 0
P20813 Cytochrome P450 2B6 Cytochrome P450 2B6 CHEMBL117 CHEMBL2354042 (1)
1 / 0
P62158 Calmodulin Unclassified protein CHEMBL117 CHEMBL1647727 (2) CHEMBL1647728 (1)
1 / 0
P08047 Transcription factor Sp1 Unclassified protein CHEMBL117 CHEMBL1058704 (1)
0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase CHEMBL117 CHEMBL1023248 (1)
1 / 1
P19793 Retinoic acid receptor RXR-alpha NR2B1 CHEMBL117 CHEMBL1794371 (1) CHEMBL1794471 (1)
0 / 0
P00918 Carbonic anhydrase 2 Lyase CHEMBL117 CHEMBL2019838 (1) CHEMBL2019839 (1)
1 / 2
P05091 Aldehyde dehydrogenase, mitochondrial Oxidoreductase CHEMBL117 CHEMBL641179 (1) CHEMBL693590 (1)
CHEMBL693591 (1) CHEMBL693592 (1)
CHEMBL693593 (1)
1 / 1
Q00534 Cyclin-dependent kinase 6 CMGC serine/threonine protein kinase family CHEMBL117 CHEMBL832923 (1)
1 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim CHEMBL117 CHEMBL862675 (1) CHEMBL862676 (1)
CHEMBL926333 (1)
0 / 0
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 CHEMBL117 CHEMBL1225717 (1) CHEMBL1780345 (1)
CHEMBL1780385 (1) CHEMBL2354055 (1)
0 / 0
P08183 Multidrug resistance protein 1 drug CHEMBL117 CHEMBL1827948 (1)
1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 CHEMBL117 CHEMBL1261122 (1) CHEMBL1614027 (1)
CHEMBL1741325 (1)
0 / 1
Q00535 Cyclin-dependent kinase 5 Cdk5 CHEMBL117 CHEMBL876996 (1)
0 / 0
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family CHEMBL117 CHEMBL876996 (1)
0 / 0
O75828 Carbonyl reductase [NADPH] 3 Enzyme CHEMBL117 CHEMBL1004501 (1) CHEMBL1004502 (1)
CHEMBL1004503 (1)
0 / 0
P11473 Vitamin D3 receptor NR1I1 CHEMBL117 CHEMBL1794376 (1) CHEMBL1794339 (1)
2 / 3
Q9Y3R4 Sialidase-2 Enzyme CHEMBL117 CHEMBL1100507 (1)
0 / 0
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL117 CHEMBL1614458 (4)
0 / 0
P16581 E-selectin Adhesion CHEMBL117 CHEMBL917094 (1)
0 / 0
O43570 Carbonic anhydrase 12 Lyase CHEMBL117 CHEMBL2019842 (1) CHEMBL2019843 (1)
1 / 2
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr CHEMBL117 CHEMBL2342404 (1)
1 / 1
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 CHEMBL117 CHEMBL2354043 (1)
0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor CHEMBL117 CHEMBL1614456 (1) CHEMBL1613803 (1)
0 / 0
P16152 Carbonyl reductase [NADPH] 1 Enzyme CHEMBL117 CHEMBL1004498 (1) CHEMBL1004499 (1)
CHEMBL1004500 (1) CHEMBL1004504 (1)
CHEMBL1004505 (2)
0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL117 CHEMBL1794584 (1)
2 / 0
O75496 Geminin Unclassified protein CHEMBL117 CHEMBL2114843 (1)
0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme CHEMBL117 CHEMBL2114807 (1)
4 / 2
P54855 UDP-glucuronosyltransferase 2B15 Enzyme CHEMBL117 CHEMBL1908090 (1)
0 / 0
P15121 Aldose reductase Enzyme CHEMBL117 CHEMBL936594 (1) CHEMBL1670631 (1)
0 / 0
P00915 Carbonic anhydrase 1 Lyase CHEMBL117 CHEMBL2019836 (1) CHEMBL2019837 (1)
0 / 0
O00519 Fatty-acid amide hydrolase 1 Enzyme CHEMBL117 CHEMBL1099470 (1)
0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein CHEMBL117 CHEMBL2114810 (1)
7 / 3
P51843 Nuclear receptor subfamily 0 group B member 1 Nuclear hormone receptor subfamily 0 group B member 1 CHEMBL117 CHEMBL2354292 (1)
2 / 2
P04150 Glucocorticoid receptor NR3C1 CHEMBL117 CHEMBL1052488 (1) CHEMBL1052489 (1)
CHEMBL1052497 (1) CHEMBL1794382 (1)
0 / 1
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 CHEMBL117 CHEMBL827396 (1) CHEMBL1105634 (1)
CHEMBL2014374 (1)
2 / 2
P14679 Tyrosinase Oxidoreductase CHEMBL117 CHEMBL814347 (1)
4 / 2
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 CHEMBL117 CHEMBL1059360 (1) CHEMBL1059361 (1)
CHEMBL1062054 (1) CHEMBL1794293 (1)
5 / 3
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 CHEMBL117 CHEMBL1225718 (1) CHEMBL1780346 (1)
CHEMBL2354050 (1)
4 / 4
Q96RI1 Bile acid receptor NR1H4 CHEMBL117 CHEMBL1794415 (1)
0 / 0
P28482 Mitogen-activated protein kinase 1 Erk CHEMBL117 CHEMBL1613808 (1)
0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 CHEMBL117 CHEMBL1225716 (1) CHEMBL1261121 (1)
CHEMBL1741322 (1) CHEMBL2354054 (1)
0 / 0
Q16790 Carbonic anhydrase 9 Lyase CHEMBL117 CHEMBL2019840 (1) CHEMBL2019841 (1)
0 / 1
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme CHEMBL117 CHEMBL1614227 (1)
3 / 3
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette CHEMBL117 CHEMBL1687393 (1) CHEMBL1687394 (1)
CHEMBL2076243 (1) CHEMBL2076828 (1)
CHEMBL2076842 (1)
2 / 0
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein CHEMBL117 CHEMBL1006005 (1)
1 / 1
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme CHEMBL117 CHEMBL1614038 (2)
2 / 2
Q9HAW9 UDP-glucuronosyltransferase 1-8 Enzyme CHEMBL117 CHEMBL1908085 (1)
0 / 0
P03372 Estrogen receptor NR3A1 CHEMBL117 CHEMBL1794364 (1) CHEMBL1794542 (1)
1 / 1
Q02880 DNA topoisomerase 2-beta Isomerase CHEMBL117 CHEMBL880106 (1)
0 / 0
P14151 L-selectin Adhesion CHEMBL117 CHEMBL917098 (1)
0 / 0
P16109 P-selectin Adhesion CHEMBL117 CHEMBL917096 (1)
1 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 CHEMBL117 CHEMBL1613777 (1) CHEMBL1741323 (1)
1 / 1
P37059 Estradiol 17-beta-dehydrogenase 2 Enzyme CHEMBL117 CHEMBL958788 (1) CHEMBL958789 (1)
0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL117 CHEMBL1261124 (1) CHEMBL1614108 (3)
CHEMBL1613886 (3) CHEMBL1741324 (1)
0 / 1
P22309 UDP-glucuronosyltransferase 1-1 Enzyme CHEMBL117 CHEMBL1908080 (1)
5 / 1
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL117 CHEMBL1614250 (3) CHEMBL1614421 (2)
4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL117 CHEMBL2114890 (1) CHEMBL2114908 (1)
0 / 0
P10275 Androgen receptor NR3C4 CHEMBL117 CHEMBL1052486 (1) CHEMBL1052498 (1)
CHEMBL1794321 (1) CHEMBL1794560 (1)
3 / 4
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 CHEMBL117 CHEMBL1059364 (1) CHEMBL1059365 (1)
0 / 0
P06239 Tyrosine-protein kinase Lck Src CHEMBL117 CHEMBL941407 (1)
0 / 1
Q04760 Lactoylglutathione lyase Enzyme CHEMBL117 CHEMBL684310 (1)
0 / 0
P35869 Aryl hydrocarbon receptor Transcription Factor CHEMBL117 CHEMBL2114849 (1)
0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme CHEMBL117 CHEMBL1613914 (1)
0 / 0
P56937 3-keto-steroid reductase Enzyme CHEMBL117 CHEMBL1106724 (1) CHEMBL1106725 (1)
0 / 0
O00255 Menin Unclassified protein CHEMBL117 CHEMBL1614257 (2) CHEMBL1614531 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL117 CHEMBL1614257 (2) CHEMBL1614531 (1)
1 / 3
Q9UN88 Gamma-aminobutyric acid receptor subunit theta GABA-A theta CHEMBL117 CHEMBL877825 (1)
0 / 0
P28472 Gamma-aminobutyric acid receptor subunit beta-3 GABA-A beta CHEMBL117 CHEMBL877825 (1)
1 / 0
P14867 Gamma-aminobutyric acid receptor subunit alpha-1 GABA-A alpha CHEMBL117 CHEMBL877825 (1)
1 / 1
P48169 Gamma-aminobutyric acid receptor subunit alpha-4 GABA-A alpha CHEMBL117 CHEMBL877825 (1)
0 / 0
O14764 Gamma-aminobutyric acid receptor subunit delta GABA-A delta CHEMBL117 CHEMBL877825 (1)
1 / 1
P31644 Gamma-aminobutyric acid receptor subunit alpha-5 GABA-A alpha CHEMBL117 CHEMBL877825 (1)
0 / 0
Q99928 Gamma-aminobutyric acid receptor subunit gamma-3 GABA-A gamma CHEMBL117 CHEMBL877825 (1)
0 / 0
P78334 Gamma-aminobutyric acid receptor subunit epsilon GABA-A epsilon CHEMBL117 CHEMBL877825 (1)
0 / 0
Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1 GABA-A gamma CHEMBL117 CHEMBL877825 (1)
0 / 0
P34903 Gamma-aminobutyric acid receptor subunit alpha-3 GABA-A alpha CHEMBL117 CHEMBL877825 (1)
0 / 0
O00591 Gamma-aminobutyric acid receptor subunit pi GABA-A pi CHEMBL117 CHEMBL877825 (1)
0 / 0
P47870 Gamma-aminobutyric acid receptor subunit beta-2 GABA-A beta CHEMBL117 CHEMBL877825 (1)
0 / 0
P18507 Gamma-aminobutyric acid receptor subunit gamma-2 GABA-A gamma CHEMBL117 CHEMBL877825 (1)
4 / 2
P18505 Gamma-aminobutyric acid receptor subunit beta-1 GABA-A beta CHEMBL117 CHEMBL877825 (1)
0 / 0
Q16445 Gamma-aminobutyric acid receptor subunit alpha-6 GABA-A alpha CHEMBL117 CHEMBL877825 (1)
0 / 0
P47869 Gamma-aminobutyric acid receptor subunit alpha-2 GABA-A alpha CHEMBL117 CHEMBL877825 (1)
1 / 0
O95067 G2/mitotic-specific cyclin-B2 Other cytosolic protein CHEMBL117 CHEMBL832848 (1)
0 / 0
P14635 G2/mitotic-specific cyclin-B1 Other cytosolic protein CHEMBL117 CHEMBL832848 (1)
0 / 0
P06493 Cyclin-dependent kinase 1 Cdc2 CHEMBL117 CHEMBL832848 (1)
0 / 0
Q8WWL7 G2/mitotic-specific cyclin-B3 Other cytosolic protein CHEMBL117 CHEMBL832848 (1)
0 / 0
P49840 Glycogen synthase kinase-3 alpha Gsk CHEMBL117 CHEMBL832706 (1)
0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk CHEMBL117 CHEMBL832706 (1)
0 / 0
P27338 Amine oxidase [flavin-containing] B Oxidoreductase CHEMBL117 CHEMBL879881 (1) CHEMBL689869 (1)
CHEMBL689870 (1) CHEMBL689871 (1)
CHEMBL731143 (1)
0 / 0
P21397 Amine oxidase [flavin-containing] A Oxidoreductase CHEMBL117 CHEMBL879881 (1) CHEMBL689869 (1)
CHEMBL689870 (1) CHEMBL689871 (1)
CHEMBL731143 (1)
1 / 1

CTD interaction (159)

compound gene gene name gene description interaction interaction type form reference
pmid
C043561 5243 ABCB1
ABC20
CD243
CLCS
GP170
MDR1
P-GP
PGY1
ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) chrysin affects the activity of ABCB1 protein affects activity
protein 15796199
C043561 5243 ABCB1
ABC20
CD243
CLCS
GP170
MDR1
P-GP
PGY1
ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) chrysin results in decreased activity of ABCB1 protein decreases activity
protein 20457140
C043561 5243 ABCB1
ABC20
CD243
CLCS
GP170
MDR1
P-GP
PGY1
ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) [chrysin results in decreased activity of ABCB1 protein] which results in decreased export of Topotecan decreases activity
/ decreases export
protein 20457140
C043561 5243 ABCB1
ABC20
CD243
CLCS
GP170
MDR1
P-GP
PGY1
ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) chrysin results in increased expression of ABCB1 protein increases expression
protein 20457140
C043561 4363 ABCC1
ABC29
ABCC
GS-X
MRP
MRP1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1 ABCC1 protein affects the reaction [chrysin results in increased transport of Glutathione] affects reaction
/ increases transport
protein 21856323
C043561 1244 ABCC2
ABC30
CMOAT
DJS
MRP2
cMRP
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 chrysin inhibits the reaction [ABCC2 protein affects the export of ochratoxin A] affects export
/ decreases reaction
protein 15955639
C043561 1244 ABCC2
ABC30
CMOAT
DJS
MRP2
cMRP
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 chrysin results in decreased activity of ABCC2 protein decreases activity
protein 20457140
C043561 1244 ABCC2
ABC30
CMOAT
DJS
MRP2
cMRP
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 [chrysin results in decreased activity of ABCC2 protein] which results in decreased export of Topotecan decreases activity
/ decreases export
protein 20457140
C043561 1244 ABCC2
ABC30
CMOAT
DJS
MRP2
cMRP
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 chrysin results in increased expression of ABCC2 protein increases expression
protein 20457140
C043561 8714 ABCC3
ABC31
EST90757
MLP2
MOAT-D
MRP3
cMOAT2
ATP-binding cassette, sub-family C (CFTR/MRP), member 3 ABCC3 protein affects the reaction [chrysin results in increased transport of Glutathione] affects reaction
/ increases transport
protein 21856323
C043561 10057 ABCC5
ABC33
EST277145
MOAT-C
MOATC
MRP5
SMRP
pABC11
ATP-binding cassette, sub-family C (CFTR/MRP), member 5 ABCC5 protein affects the reaction [chrysin results in increased transport of Glutathione] affects reaction
/ increases transport
protein 21856323
C043561 9429 ABCG2
ABC15
ABCP
BCRP
BCRP1
BMDP
CD338
CDw338
EST157481
GOUT1
MRX
MXR
MXR1
UAQTL1
ATP-binding cassette, sub-family G (WHITE), member 2 chrysin inhibits the reaction [ABCG2 protein results in increased secretion of Mitoxantrone] decreases reaction
/ increases secretion
protein 17093006
C043561 9429 ABCG2
ABC15
ABCP
BCRP
BCRP1
BMDP
CD338
CDw338
EST157481
GOUT1
MRX
MXR
MXR1
UAQTL1
ATP-binding cassette, sub-family G (WHITE), member 2 chrysin inhibits the reaction [ABCG2 protein results in increased transport of Nitrofurantoin] decreases reaction
/ increases transport
protein 17093006
C043561 9429 ABCG2
ABC15
ABCP
BCRP
BCRP1
BMDP
CD338
CDw338
EST157481
GOUT1
MRX
MXR
MXR1
UAQTL1
ATP-binding cassette, sub-family G (WHITE), member 2 chrysin results in decreased activity of ABCG2 protein decreases activity
protein 20457140
C043561 9429 ABCG2
ABC15
ABCP
BCRP
BCRP1
BMDP
CD338
CDw338
EST157481
GOUT1
MRX
MXR
MXR1
UAQTL1
ATP-binding cassette, sub-family G (WHITE), member 2 [chrysin results in decreased activity of ABCG2 protein] which results in decreased export of Topotecan decreases activity
/ decreases export
protein 20457140
C043561 9429 ABCG2
ABC15
ABCP
BCRP
BCRP1
BMDP
CD338
CDw338
EST157481
GOUT1
MRX
MXR
MXR1
UAQTL1
ATP-binding cassette, sub-family G (WHITE), member 2 chrysin results in decreased expression of ABCG2 mRNA decreases expression
mRNA 20816778
C043561 9429 ABCG2
ABC15
ABCP
BCRP
BCRP1
BMDP
CD338
CDw338
EST157481
GOUT1
MRX
MXR
MXR1
UAQTL1
ATP-binding cassette, sub-family G (WHITE), member 2 chrysin results in increased expression of ABCG2 mRNA increases expression
mRNA 17077187
C043561 9429 ABCG2
ABC15
ABCP
BCRP
BCRP1
BMDP
CD338
CDw338
EST157481
GOUT1
MRX
MXR
MXR1
UAQTL1
ATP-binding cassette, sub-family G (WHITE), member 2 chrysin results in increased expression of ABCG2 protein increases expression
protein 20457140
C043561 196 AHR
bHLHe76
aryl hydrocarbon receptor chrysin affects the activity of AHR protein affects activity
protein 19286049
C043561 196 AHR
bHLHe76
aryl hydrocarbon receptor chrysin binds to and results in increased activity of AHR protein affects binding
/ increases activity
protein 14644660
16972788
C043561 196 AHR
bHLHe76
aryl hydrocarbon receptor [chrysin co-treated with Methylcholanthrene] affects the activity of AHR protein affects activity
/ affects cotreatment
protein 19286049
C043561 196 AHR
bHLHe76
aryl hydrocarbon receptor [chrysin co-treated with Tetrachlorodibenzodioxin] affects the activity of AHR protein affects activity
/ affects cotreatment
protein 19286049
C043561 196 AHR
bHLHe76
aryl hydrocarbon receptor chrysin inhibits the reaction [AHR protein binds to CYP1A1 promoter] affects binding
/ decreases reaction
protein 17256720
C043561 196 AHR
bHLHe76
aryl hydrocarbon receptor chrysin inhibits the reaction [AHR protein binds to UGT1A1 promoter] affects binding
/ decreases reaction
protein 17256720
C043561 196 AHR
bHLHe76
aryl hydrocarbon receptor chrysin inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein] affects binding
/ decreases reaction
protein 17256720
C043561 196 AHR
bHLHe76
aryl hydrocarbon receptor chrysin promotes the reaction [AHR protein binds to CYP1A1 promoter] affects binding
/ increases reaction
protein 16972788
C043561 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) BCL2 protein inhibits the reaction [chrysin results in decreased phosphorylation of and results in decreased activity of AKT1 protein] decreases activity
/ decreases phosphorylation
/ decreases reaction
protein 16215670
C043561 207 AKT1
AKT
CWS6
PKB
PKB-ALPHA
PRKBA
RAC
RAC-ALPHA
v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) chrysin results in decreased phosphorylation of and results in decreased activity of AKT1 protein decreases activity
/ decreases phosphorylation
protein 16215670
C043561 405 ARNT
HIF-1-beta
HIF-1beta
HIF1-beta
HIF1B
HIF1BETA
TANGO
bHLHe2
aryl hydrocarbon receptor nuclear translocator chrysin promotes the reaction [ARNT protein binds to CYP1A1 promoter] affects binding
/ increases reaction
protein 16972788
C043561 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 BCL2 protein inhibits the reaction [chrysin results in decreased expression of XIAP protein] decreases expression
/ decreases reaction
protein 16215670
C043561 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 BCL2 protein inhibits the reaction [chrysin results in decreased phosphorylation of and results in decreased activity of AKT1 protein] decreases activity
/ decreases phosphorylation
/ decreases reaction
protein 16215670
C043561 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 BCL2 protein inhibits the reaction [chrysin results in increased cleavage of and results in increased activity of CASP3 protein] decreases reaction
/ increases activity
/ increases cleavage
protein 16215670
C043561 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 BCL2 protein inhibits the reaction [chrysin results in increased degradation of PLCG1 protein] decreases reaction
/ increases degradation
protein 16215670
C043561 596 BCL2
Bcl-2
PPP1R50
B-cell CLL/lymphoma 2 BCL2 protein results in decreased susceptibility to chrysin decreases response to substance
protein 16215670
C043561 834 CASP1
ICE
IL1BC
P45
caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36) chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP1 protein] affects cotreatment
/ decreases reaction
/ increases activity
protein 21515303
C043561 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) BCL2 protein inhibits the reaction [chrysin results in increased cleavage of and results in increased activity of CASP3 protein] decreases reaction
/ increases activity
/ increases cleavage
protein 16215670
C043561 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) chrysin inhibits the reaction [Topotecan results in increased activity of CASP3 protein] decreases reaction
/ increases activity
protein 20457140
C043561 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) chrysin promotes the reaction [TNFSF10 protein results in increased degradation of CASP3 protein] increases degradation
/ increases reaction
protein 21195158
C043561 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) chrysin results in increased cleavage of and results in increased activity of CASP3 protein increases activity
/ increases cleavage
protein 16215670
C043561 836 CASP3
CPP32
CPP32B
SCA-1
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) chrysin results in increased cleavage of CASP3 protein increases cleavage
protein 18331776
19397994
C043561 841 CASP8
ALPS2B
CAP4
Casp-8
FLICE
MACH
MCH5
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) chrysin inhibits the reaction [Topotecan results in increased activity of CASP8 protein] decreases reaction
/ increases activity
protein 20457140
C043561 841 CASP8
ALPS2B
CAP4
Casp-8
FLICE
MACH
MCH5
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) chrysin promotes the reaction [TNFSF10 protein results in increased degradation of CASP8 protein] increases degradation
/ increases reaction
protein 21195158
C043561 842 CASP9
APAF-3
APAF3
ICE-LAP6
MCH6
PPP1R56
caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) chrysin results in increased cleavage of CASP9 protein increases cleavage
protein 18331776
C043561 891 CCNB1
CCNB
cyclin B1 chrysin results in decreased expression of CCNB1 mRNA decreases expression
mRNA 18331776
19397994
C043561 891 CCNB1
CCNB
cyclin B1 chrysin results in decreased expression of CCNB1 protein decreases expression
protein 18331776
19397994
C043561 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) chrysin results in increased expression of CDKN1A mRNA increases expression
mRNA 19397994
C043561 1026 CDKN1A
CAP20
CDKN1
CIP1
MDA-6
P21
SDI1
WAF1
p21CIP1
cyclin-dependent kinase inhibitor 1A (p21, Cip1) chrysin results in increased expression of CDKN1A protein increases expression
protein 19397994
C043561 1031 CDKN2C
INK4C
p18
p18-INK4C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) chrysin results in decreased expression of CDKN2C mRNA decreases expression
mRNA 18331776
C043561 1499 CTNNB1
CTNNB
MRD19
armadillo
catenin (cadherin-associated protein), beta 1, 88kDa chrysin inhibits the reaction [Topotecan results in increased cleavage of CTNNB1 protein] decreases reaction
/ increases cleavage
protein 20457140
C043561 1588 CYP19A1
ARO
ARO1
CPV1
CYAR
CYP19
CYPXIX
P-450AROM
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) chrysin binds to and results in decreased activity of CYP19A1 protein affects binding
/ decreases activity
protein 9435150
C043561 1588 CYP19A1
ARO
ARO1
CPV1
CYAR
CYP19
CYPXIX
P-450AROM
cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) chrysin results in decreased activity of CYP19A1 protein decreases activity
protein 10403137
15319488
C043561 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) chrysin inhibits the reaction [AHR protein binds to CYP1A1 promoter] affects binding
/ decreases reaction
promoter 17256720
C043561 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) chrysin inhibits the reaction [CYP1A1 results in increased activity of Benzo(a)pyrene] decreases reaction
/ increases activity
11752233
C043561 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) chrysin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] decreases reaction
/ increases activity
protein 19766177
C043561 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) chrysin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] decreases reaction
/ increases expression
mRNA 17012224
C043561 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) chrysin promotes the reaction [AHR protein binds to CYP1A1 promoter] affects binding
/ increases reaction
promoter 16972788
C043561 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) chrysin promotes the reaction [ARNT protein binds to CYP1A1 promoter] affects binding
/ increases reaction
promoter 16972788
C043561 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) chrysin promotes the reaction [ESR1 protein binds to CYP1A1 promoter] affects binding
/ increases reaction
promoter 16972788
C043561 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) chrysin results in decreased activity of CYP1A1 protein decreases activity
protein 21053930
21482471
C043561 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) chrysin results in increased activity of CYP1A1 protein increases activity
protein 19766177
C043561 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) chrysin results in increased expression of CYP1A1 mRNA increases expression
mRNA 20816778
C043561 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) chrysin results in increased expression of CYP1A1 protein increases expression
protein 16972788
C043561 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) CYP1A1 protein results in increased metabolism of chrysin increases metabolic processing
protein 19666078
C043561 1543 CYP1A1
AHH
AHRR
CP11
CYP1
P1-450
P450-C
P450DX
cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) [CYP1A1 protein results in increased metabolism of chrysin] which results in increased chemical synthesis of baicalein increases chemical synthesis
/ increases metabolic processing
protein 19666078
C043561 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) chrysin results in decreased activity of CYP1A2 protein decreases activity
protein 20806393
21053930
C043561 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) CYP1A2 protein results in increased metabolism of chrysin increases metabolic processing
protein 19666078
C043561 1544 CYP1A2
CP12
P3-450
P450(PA)
cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) [CYP1A2 protein results in increased metabolism of chrysin] which results in increased chemical synthesis of baicalein increases chemical synthesis
/ increases metabolic processing
protein 19666078
C043561 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) chrysin binds to and results in decreased activity of CYP1B1 protein affects binding
/ decreases activity
protein 21053930
C043561 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) chrysin results in decreased activity of CYP1B1 protein decreases activity
protein 21482471
C043561 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) CYP1B1 protein results in increased metabolism of chrysin increases metabolic processing
protein 19666078
C043561 1545 CYP1B1
CP1B
CYPIB1
GLC3A
P4501B1
cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) [CYP1B1 protein results in increased metabolism of chrysin] which results in increased chemical synthesis of baicalein increases chemical synthesis
/ increases metabolic processing
protein 19666078
C043561 1559 CYP2C9
CPC9
CYP2C
CYP2C10
CYPIIC9
P450IIC9
cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) chrysin inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen] decreases reaction
/ increases hydroxylation
protein 21053930
C043561 1576 CYP3A4
CP33
CP34
CYP3A
CYP3A3
CYPIIIA3
CYPIIIA4
HLP
NF-25
P450C3
P450PCN1
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) chrysin binds to and results in decreased activity of CYP3A4 protein affects binding
/ decreases activity
protein 21053930
C043561 1576 CYP3A4
CP33
CP34
CYP3A
CYP3A3
CYPIIIA3
CYPIIIA4
HLP
NF-25
P450C3
P450PCN1
cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) chrysin inhibits the reaction [Calcitriol results in increased activity of CYP3A4 protein] decreases reaction
/ increases activity
protein 19766177
C043561 1906 EDN1
ET1
HDLCQ7
PPET1
endothelin 1 chrysin results in increased expression of EDN1 mRNA increases expression
mRNA 18457675
C043561 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 chrysin binds to and results in increased activity of ESR1 protein affects binding
/ increases activity
protein 9751507
16972788
C043561 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 chrysin promotes the reaction [ESR1 protein binds to CYP1A1 promoter] affects binding
/ increases reaction
protein 16972788
C043561 2099 ESR1
ER
ESR
ESRA
ESTRR
Era
NR3A1
estrogen receptor 1 chrysin promotes the reaction [ESR1 protein binds to TFF1 promoter] affects binding
/ increases reaction
protein 16972788
C043561 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) chrysin binds to and results in increased activity of ESR2 protein affects binding
/ increases activity
protein 9751507
C043561 2100 ESR2
ER-BETA
ESR-BETA
ESRB
ESTRB
Erb
NR3A2
estrogen receptor 2 (ER beta) chrysin binds to ESR2 protein affects binding
protein 12224631
C043561 9415 FADS2
D6D
DES6
FADSD6
LLCDL2
SLL0262
TU13
fatty acid desaturase 2 (EC:1.14.19.-) chrysin results in decreased expression of FADS2 mRNA decreases expression
mRNA 20816778
C043561 2203 FBP1
FBP
fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) chrysin results in decreased expression of FBP1 mRNA decreases expression
mRNA 18331776
C043561 2353 FOS
AP-1
C-FOS
p55
FBJ murine osteosarcoma viral oncogene homolog chrysin inhibits the reaction [TNF protein results in increased activity of [FOS protein binds to JUN protein]] affects binding
/ decreases reaction
/ increases activity
protein 15322261
C043561 4616 GADD45B
GADD45BETA
MYD118
growth arrest and DNA-damage-inducible, beta chrysin results in increased expression of GADD45B mRNA increases expression
mRNA 18331776
C043561 4616 GADD45B
GADD45BETA
MYD118
growth arrest and DNA-damage-inducible, beta chrysin results in increased expression of GADD45B protein increases expression
protein 18331776
C043561 3122 HLA-DRA
HLA-DRA1
MLRW
major histocompatibility complex, class II, DR alpha chrysin results in decreased expression of HLA-DRA mRNA decreases expression
mRNA 20816778
C043561 3383 ICAM1
BB2
CD54
P3.58
intercellular adhesion molecule 1 chrysin inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] decreases reaction
/ increases expression
mRNA 15322261
C043561 3383 ICAM1
BB2
CD54
P3.58
intercellular adhesion molecule 1 chrysin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] decreases reaction
/ increases expression
protein 15322261
C043561 3600 IL15
IL-15
interleukin 15 chrysin results in decreased expression of IL15 mRNA decreases expression
mRNA 20816778
C043561 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B mRNA] affects cotreatment
/ decreases reaction
/ increases expression
mRNA 21515303
C043561 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta chrysin inhibits the reaction [IL1B protein results in increased phosphorylation of NFKBIA protein] decreases reaction
/ increases phosphorylation
protein 18377686
C043561 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta chrysin inhibits the reaction [IL1B protein results in increased secretion of IL8 protein] decreases reaction
/ increases secretion
protein 18377686
C043561 3553 IL1B
IL-1
IL1-BETA
IL1F2
interleukin 1, beta chrysin results in decreased expression of IL1B mRNA decreases expression
mRNA 20816778
C043561 3554 IL1R1
CD121A
D2S1473
IL-1R-alpha
IL1R
IL1RA
P80
interleukin 1 receptor, type I chrysin results in decreased expression of IL1R1 mRNA decreases expression
mRNA 20816778
C043561 3565 IL4
BCGF-1
BCGF1
BSF-1
BSF1
IL-4
interleukin 4 chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 mRNA] affects cotreatment
/ decreases reaction
/ increases expression
mRNA 21515303
C043561 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA] affects cotreatment
/ decreases reaction
/ increases expression
mRNA 21515303
C043561 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) chrysin results in decreased expression of IL6 mRNA decreases expression
mRNA 20816778
C043561 3569 IL6
BSF2
HGF
HSF
IFNB2
IL-6
interleukin 6 (interferon, beta 2) chrysin results in increased expression of IL6 mRNA increases expression
mRNA 18457675
C043561 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 chrysin inhibits the reaction [IL1B protein results in increased secretion of IL8 protein] decreases reaction
/ increases secretion
protein 18377686
C043561 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 chrysin results in increased expression of IL8 mRNA increases expression
mRNA 18457675
C043561 3725 JUN
AP-1
AP1
c-Jun
jun proto-oncogene chrysin inhibits the reaction [TNF protein results in increased activity of [FOS protein binds to JUN protein]] affects binding
/ decreases reaction
/ increases activity
protein 15322261
C043561 3725 JUN
AP-1
AP1
c-Jun
jun proto-oncogene chrysin inhibits the reaction [TNF protein results in increased expression of JUN mRNA] decreases reaction
/ increases expression
mRNA 15322261
C043561 4792 NFKBIA
IKBA
MAD-3
NFKBI
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased degradation of NFKBIA protein] affects cotreatment
/ decreases reaction
/ increases degradation
protein 21515303
C043561 4792 NFKBIA
IKBA
MAD-3
NFKBI
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha chrysin inhibits the reaction [IL1B protein results in increased phosphorylation of NFKBIA protein] decreases reaction
/ increases phosphorylation
protein 18377686
C043561 5335 PLCG1
NCKAP3
PLC-II
PLC1
PLC148
PLCgamma1
phospholipase C, gamma 1 (EC:3.1.4.11) BCL2 protein inhibits the reaction [chrysin results in increased degradation of PLCG1 protein] decreases reaction
/ increases degradation
protein 16215670
C043561 5335 PLCG1
NCKAP3
PLC-II
PLC1
PLC148
PLCgamma1
phospholipase C, gamma 1 (EC:3.1.4.11) chrysin results in increased degradation of PLCG1 protein increases degradation
protein 16215670
C043561 5465 PPARA
NR1C1
PPAR
PPARalpha
hPPAR
peroxisome proliferator-activated receptor alpha chrysin results in decreased expression of PPARA mRNA decreases expression
mRNA 20816778
C043561 8000 PSCA
PRO232
prostate stem cell antigen chrysin results in decreased expression of PSCA mRNA decreases expression
mRNA 18331776
C043561 5743 PTGS2
COX-2
COX2
GRIPGHS
PGG/HS
PGHS-2
PHS-2
hCox-2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) chrysin results in increased expression of PTGS2 mRNA increases expression
mRNA 18457675
C043561 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A Acetylcysteine inhibits the reaction [chrysin results in increased activity of RELA protein] decreases reaction
/ increases activity
protein 18457675
C043561 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of RELA protein] affects cotreatment
/ affects localization
/ decreases reaction
protein 21515303
C043561 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A chrysin results in increased activity of RELA protein increases activity
protein 18457675
C043561 5970 RELA
NFKB3
p65
v-rel avian reticuloendotheliosis viral oncogene homolog A SB 203580 inhibits the reaction [chrysin results in increased activity of RELA protein] decreases reaction
/ increases activity
protein 18457675
C043561 6309 SC5D
ERG3
S5DES
SC5DL
sterol-C5-desaturase (EC:1.14.21.6) chrysin results in decreased expression of SC5D mRNA decreases expression
mRNA 20816778
C043561 6319 SCD
FADS5
MSTP008
SCD1
SCDOS
stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) chrysin results in decreased expression of SCD mRNA decreases expression
mRNA 20816778
C043561 2810 SFN
YWHAS
stratifin chrysin results in increased expression of SFN mRNA increases expression
mRNA 18331776
C043561 2810 SFN
YWHAS
stratifin chrysin results in increased expression of SFN protein increases expression
protein 18331776
C043561 6817 SULT1A1
HAST1/HAST2
P-PST
PST
ST1A1
ST1A3
STP
STP1
TSPST1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) SULT1A1 protein SNP results in increased sulfation of chrysin increases sulfation
protein 17293380
C043561 6783 SULT1E1
EST
EST-1
ST1E1
STE
sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4) SULT1E1 protein results in increased sulfation of and results in decreased activity of chrysin decreases activity
/ increases sulfation
protein 17293380
C043561 29110 TBK1
NAK
T2K
TANK-binding kinase 1 (EC:2.7.11.1) chrysin results in decreased activity of TBK1 protein decreases activity
protein 19426678
C043561 7031 TFF1
BCEI
D21S21
HP1.A
HPS2
pNR-2
pS2
trefoil factor 1 chrysin promotes the reaction [ESR1 protein binds to TFF1 promoter] affects binding
/ increases reaction
promoter 16972788
C043561 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA] affects cotreatment
/ decreases reaction
/ increases expression
mRNA 21515303
C043561 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein] affects cotreatment
/ decreases reaction
/ increases secretion
protein 21515303
C043561 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor chrysin inhibits the reaction [TNF protein results in increased activity of [FOS protein binds to JUN protein]] affects binding
/ decreases reaction
/ increases activity
protein 15322261
C043561 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor chrysin inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] decreases reaction
/ increases expression
protein 15322261
C043561 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor chrysin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] decreases reaction
/ increases expression
protein 15322261
C043561 7124 TNF
DIF
TNF-alpha
TNFA
TNFSF2
tumor necrosis factor chrysin inhibits the reaction [TNF protein results in increased expression of JUN mRNA] decreases reaction
/ increases expression
protein 15322261
C043561 8743 TNFSF10
APO2L
Apo-2L
CD253
TL2
TRAIL
tumor necrosis factor (ligand) superfamily, member 10 chrysin promotes the reaction [TNFSF10 protein results in increased degradation of CASP3 protein] increases degradation
/ increases reaction
protein 21195158
C043561 8743 TNFSF10
APO2L
Apo-2L
CD253
TL2
TRAIL
tumor necrosis factor (ligand) superfamily, member 10 chrysin promotes the reaction [TNFSF10 protein results in increased degradation of CASP8 protein] increases degradation
/ increases reaction
protein 21195158
C043561 8743 TNFSF10
APO2L
Apo-2L
CD253
TL2
TRAIL
tumor necrosis factor (ligand) superfamily, member 10 chrysin results in increased susceptibility to TNFSF10 protein increases response to substance
protein 21195158
C043561 7157 TP53
BCC7
LFS1
P53
TRP53
tumor protein p53 chrysin results in increased degradation of TP53 protein increases degradation
protein 14634213
C043561 9540 TP53I3
PIG3
tumor protein p53 inducible protein 3 chrysin results in increased expression of TP53I3 mRNA increases expression
mRNA 18331776
19397994
C043561 9540 TP53I3
PIG3
tumor protein p53 inducible protein 3 chrysin results in increased expression of TP53I3 protein increases expression
protein 18331776
19397994
C043561 8626 TP63
AIS
B(p51A)
B(p51B)
EEC3
KET
LMS
NBP
OFC8
RHS
SHFM4
TP53CP
TP53L
TP73L
p40
p51
p53CP
p63
p73H
p73L
tumor protein p63 chrysin results in increased expression of TP63 protein increases expression
protein 18331776
19397994
C043561 7161 TP73
P73
tumor protein p73 chrysin results in increased expression of TP73 protein increases expression
protein 18331776
19397994
C043561 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [chrysin results in increased expression of UGT1A1 mRNA] decreases reaction
/ increases expression
mRNA 17256720
C043561 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [chrysin results in increased expression of UGT1A1 mRNA] decreases reaction
/ increases expression
mRNA 17256720
C043561 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) chrysin inhibits the reaction [AHR protein binds to UGT1A1 promoter] affects binding
/ decreases reaction
promoter 17256720
C043561 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) chrysin promotes the reaction [UGT1A1 protein affects the glucuronidation of Bilirubin] affects glucuronidation
/ increases reaction
protein 10950852
C043561 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) chrysin promotes the reaction [UGT1A1 protein affects the glucuronidation of Ethinyl Estradiol] affects glucuronidation
/ increases reaction
protein 10950852
C043561 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) chrysin promotes the reaction [UGT1A1 protein results in increased glucuronidation of Quercetin] increases glucuronidation
/ increases reaction
protein 11442279
C043561 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) chrysin results in increased expression of UGT1A1 increases expression
16003560
C043561 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) chrysin results in increased expression of UGT1A1 mRNA increases expression
mRNA 10950852
11442279
15104253
17256720
C043561 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) chrysin results in increased expression of UGT1A1 protein increases expression
protein 10950852
11442279
C043561 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) SB 203580 inhibits the reaction [chrysin results in increased expression of UGT1A1 mRNA] decreases reaction
/ increases expression
mRNA 17256720
C043561 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) U 0126 inhibits the reaction [chrysin results in increased expression of UGT1A1 mRNA] decreases reaction
/ increases expression
mRNA 17256720
C043561 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) UGT1A1 protein affects the glucuronidation of chrysin affects glucuronidation
protein 10950852
C043561 54658 UGT1A1
BILIQTL1
GNT1
HUG-BR1
UDPGT
UDPGT_1-1
UGT1
UGT1A
UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) UGT1A1 protein results in increased glucuronidation of chrysin increases glucuronidation
protein 14557274
C043561 54575 UGT1A10
UDPGT
UGT-1J
UGT1-10
UGT1.10
UGT1J
UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) UGT1A10 protein results in increased glucuronidation of chrysin increases glucuronidation
protein 14557274
C043561 54578 UGT1A6
GNT1
HLUGP
HLUGP1
UDPGT
UDPGT_1-6
UGT1
UGT1A6S
UGT1F
UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) UGT1A6 protein affects the glucuronidation of chrysin affects glucuronidation
protein 10950852
C043561 54577 UGT1A7
UDPGT
UDPGT_1-7
UGT-1G
UGT1-07
UGT1.7
UGT1G
UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) UGT1A7 protein results in increased glucuronidation of chrysin increases glucuronidation
protein 14557274
C043561 54576 UGT1A8
UDPGT
UDPGT_1-8
UGT-1H
UGT1-08
UGT1.8
UGT1A8S
UGT1H
UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) UGT1A8 protein results in increased glucuronidation of chrysin increases glucuronidation
protein 14557274
C043561 54600 UGT1A9
HLUGP4
LUGP4
UDPGT
UDPGT_1-9
UGT-1I
UGT1-09
UGT1-9
UGT1.9
UGT1AI
UGT1I
UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) UGT1A9 protein affects the glucuronidation of chrysin affects glucuronidation
protein 10950852
C043561 54600 UGT1A9
HLUGP4
LUGP4
UDPGT
UDPGT_1-9
UGT-1I
UGT1-09
UGT1-9
UGT1.9
UGT1AI
UGT1I
UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) UGT1A9 protein results in increased glucuronidation of chrysin increases glucuronidation
protein 14557274
C043561 7366 UGT2B15
HLUG4
UDPGT_2B8
UDPGT2B15
UDPGTH3
UGT2B8
UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) UGT2B15 protein results in increased metabolism of chrysin increases metabolic processing
protein 7835232
C043561 7402 UTRN
DMDL
DRP
DRP1
utrophin chrysin results in increased expression of UTRN mRNA increases expression
mRNA 22028826
C043561 7412 VCAM1
CD106
INCAM-100
vascular cell adhesion molecule 1 chrysin results in increased expression of VCAM1 mRNA increases expression
mRNA 18457675
C043561 331 XIAP
API3
BIRC4
IAP-3
ILP1
MIHA
XLP2
hIAP-3
hIAP3
X-linked inhibitor of apoptosis BCL2 protein inhibits the reaction [chrysin results in decreased expression of XIAP protein] decreases expression
/ decreases reaction
protein 16215670
C043561 331 XIAP
API3
BIRC4
IAP-3
ILP1
MIHA
XLP2
hIAP-3
hIAP3
X-linked inhibitor of apoptosis chrysin results in decreased expression of XIAP protein decreases expression
protein 16215670

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (89)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#300018 46,xy sex reversal 2; srxy2 P51843
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#300200 Adrenal hypoplasia, congenital; ahc P51843
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#103780 Alcohol dependence P47869
#610251 Alcohol sensitivity, acute P05091
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#614490 Blood group, junior system; jr Q9UNQ0
%606641 Body mass index; bmi P37231
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#300615 Brunner syndrome P21397
#609338 Carotid intimal medial thickness 1 P37231
#114500 Colorectal cancer; crc P84022
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#119900 Digital clubbing, isolated congenital P15428
#607208 Dravet syndrome P18507
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#237500 Dubin-johnson syndrome; djs Q92887
#614546 Efavirenz, poor metabolism of P20813
#607681 Epilepsy, childhood absence, susceptibility to, 2; eca2 P18507
#612269 Epilepsy, childhood absence, susceptibility to, 5; eca5 P28472
#613060 Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 O14764
#611136 Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 P14867
#133239 Esophageal cancer P04637
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#604233 Generalized epilepsy with febrile seizures plus, type 1; gefsp1 P18507
#611277 Generalized epilepsy with febrile seizures plus, type 3; gefsp3 P18507
#143500 Gilbert syndrome P22309
P22310
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#137800 Glioma susceptibility 1; glm1 P37231
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#143860 Hyperchlorhidrosis, isolated O43570
#145000 Hyperparathyroidism 1; hrpt1 O00255
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#612244 Inflammatory bowel disease 13; ibd13 P08183
#601626 Leukemia, acute myeloid; aml P36888
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#211980 Lung cancer P04637
#174800 Mccune-albright syndrome; mas P63092
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#601665 Obesity P37231
#166350 Osseous heteroplasia, progressive; poh P63092
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#260540 Parkinson-dementia syndrome P10636
#604229 Peters anomaly Q16678
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
%612223 Stature quantitative trait locus 11; stqtl11 Q00534
#601367 Stroke, ischemic P16109
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#614916 Ventricular tachycardia, catecholaminergic polymorphic, 4; cpvt4 P62158
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#278300 Xanthinuria, type i P47989

KEGG DISEASE (87)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00783 Febrile seizures O14764 (related)
P18507 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
P04637 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00026 Endometrial Cancer P03372 (marker)
P04637 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
P11511 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00027 Ovarian cancer P04637 (related)
P38398 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
P38398 (related)
H00032 Thyroid cancer P04637 (related)
P37231 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
P14679 (marker)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
P35354 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H01071 Acute alcohol sensitivity P05091 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00794 Aromatase excess syndrome P11511 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00808 Idiopathic generalized epilepsies (IGEs) P14867 (related)
P18507 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00548 Brunner syndrome P21397 (related)
H00208 Hyperbilirubinemia P22309 (related)
Q92887 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)
H00192 Xanthinuria P47989 (related)
H00552 Glycerol kinase deficiency (GKD) P51843 (related)
H00607 46,XY disorders of sex development (Disorders of gonadal development) P51843 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
Q16637 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)

Diseases related to CTD interactions

6 disease from interactions of metabolites

MeSH disease OMIM compound disease name evidence type reference
pmid
D000707 C043561 Anaphylaxis therapeutic
21515303
D003110 C043561 Colonic Neoplasms therapeutic
19914226
D007249 C043561 Inflammation therapeutic
23194824
D007680 C043561 Kidney Neoplasms therapeutic
23194824
D008175 C043561 Lung Neoplasms therapeutic
21856323
D011230 C043561 Precancerous Conditions therapeutic
19914226