Populus spp.
Species
KNApSAcK Entry
| Organism name | Populus spp. |
|---|---|
| Genus | Populus |
| Family | Salicaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Populus |
|---|---|
| Linked NCBI taxonomy ID | 3689 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Salicaceae |
|---|---|
| ID | 3688 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (11)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00000992
|
Pinocembrin
|
CHEMBL70518
CHEMBL399910 CHEMBL399249 |
C016063
|
18 / 23 / 23 | 5 / 0 | No. 25 | No. 14 |
|
|
C00002631
|
(+)-Lirioresinol B
/ (+)-Syringaresinol |
CHEMBL361362
CHEMBL402653 |
C042192
|
1 / 0 / 0 | No. 38 | No. 21 |
|
|
|
C00002672
|
Salicin
/ Saligenin beta-D-glucopyranoside |
CHEMBL334657
CHEMBL462997 CHEMBL1595746 |
C005696
|
5 / 1 / 4 | No. 45 | No. 72 |
|
|
|
C00003794
|
Chrysin
/ 5,7-Dihydroxyflavone / 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one |
CHEMBL117
|
C043561
|
100 / 89 / 87 | 69 / 6 | No. 76 | No. 15 |
|
|
C00003795
|
Tectochrysin
/ 5-hydroxy-7-methoxyflavone |
CHEMBL164841
|
12 / 19 / 14 | No. 76 | No. 15 |
|
||
|
C00006934
|
Pinostrobin chalcone
/ 2',6'-Dihydroxy-4'-methoxychalcone |
CHEMBL317221
CHEMBL1705800 |
3 / 1 / 2 | No. 92 | No. 13 |
|
||
|
C00006935
|
Cardamomin
|
CHEMBL378104
|
13 / 18 / 14 | No. 92 | No. 13 |
|
||
|
C00000170
|
trans-Cinnamate
/ trans-Cinnamic acid |
CHEMBL27246
|
5 / 2 / 2 | No. 904 | No. 6 |
|
||
|
C00002644
|
Catechol
/ Pyrocatechol |
CHEMBL280998
|
C034221
|
148 / 82 / 64 | 22 / 5 | No. 1590 | No. 82 |
|
|
C00002766
|
Phenetyl caffeate
|
CHEMBL319244
CHEMBL1397711 |
C055494
|
139 / 92 / 90 | 37 / 20 | No. 1829 |
|
|
|
C00002768
|
Prenyl cafeate
|
CHEMBL471184
|
No. 2545 |
|
Human Protein / Gene in interactions
243 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000992 C00002644 C00002766 C00003794 C00003795 C00006934 | 0 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000992 C00002644 C00002766 C00003794 C00003795 C00006935 | 4 / 3 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000992 C00002644 C00002766 C00003794 C00003795 C00006934 | 1 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000992 C00002644 C00002672 C00002766 C00006934 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000992 C00002644 C00002766 C00003794 C00003795 | 0 / 1 |
| O75496 | Geminin | Unclassified protein | C00002644 C00002766 C00003794 C00003795 C00006935 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00002644 C00002766 C00003794 C00003795 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00000992 C00002766 C00003794 C00006935 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000992 C00002766 C00003794 C00006935 | 1 / 2 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000992 C00002644 C00002766 C00003794 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00000170 C00002644 C00002766 C00003794 | 1 / 1 |
| Q99700 | Ataxin-2 | Unclassified protein | C00002644 C00002766 C00003794 C00006935 | 1 / 1 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000992 C00002644 C00002766 C00003794 | 3 / 3 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000992 C00002644 C00002766 C00003794 | 1 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00002644 C00002672 C00002766 C00003794 | 0 / 3 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00002644 C00002766 C00003794 | 0 / 1 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002644 C00002766 C00003794 | 2 / 2 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002644 C00002766 C00003794 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00000992 C00002766 C00003795 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00000170 C00002766 C00003794 | 0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00002644 C00002766 C00003794 | 0 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00002644 C00002766 C00003794 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002644 C00002766 C00003794 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00002644 C00002766 C00003794 | 4 / 1 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00002644 C00002672 C00002766 | 1 / 1 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00000992 C00003794 C00006935 | 7 / 3 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00002644 C00002766 C00003794 | 1 / 1 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00002644 C00002766 C00003794 | 1 / 2 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00002644 C00002766 C00003794 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002644 C00002672 C00006935 | 0 / 0 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00000170 C00002644 C00003794 | 1 / 1 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00002644 C00002766 C00006935 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000992 C00002644 C00002766 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00002644 C00002766 C00003794 | 0 / 1 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00000992 C00002644 C00002766 | 0 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00002644 C00002766 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00002644 C00002766 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00002644 C00002766 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00002644 C00002766 | 11 / 10 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00000992 C00003794 | 0 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00002766 C00003795 | 4 / 2 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00002766 C00003795 | 3 / 2 |
| P29466 | Caspase-1 | C14 | C00002644 C00002766 | 0 / 0 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00002644 C00002766 | 0 / 0 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00002644 C00002766 | 1 / 1 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00002644 C00002766 | 0 / 0 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00002644 C00002766 | 0 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00002644 C00002766 | 0 / 0 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00002644 C00002766 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00002644 C00002766 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00002644 C00002766 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00002644 C00002766 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00002644 C00002766 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00002644 C00002766 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00002644 C00002766 | 0 / 0 |
| P11309 | Serine/threonine-protein kinase pim-1 | Pim | C00000992 C00003794 | 0 / 0 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00000992 C00003794 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00003794 C00003795 | 1 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00002644 C00002766 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00002644 C00002766 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00002644 C00002766 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00002644 C00002766 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00002644 C00002766 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00002644 C00002766 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00002644 C00002766 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00002644 C00002766 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00002644 C00002766 | 1 / 2 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00002644 C00002766 | 1 / 8 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00002644 C00002766 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00002644 C00002766 | 0 / 0 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00002644 C00002766 | 2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00002644 C00002766 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00002644 C00002766 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00002644 C00002766 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00002644 C00002766 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00002644 C00002766 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00002644 C00002766 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00002644 C00002766 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00002644 C00002766 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00002644 C00002766 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00002644 C00002766 | 1 / 1 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00002644 C00002766 | 0 / 0 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00002644 C00002766 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00002644 C00002766 | 1 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00002644 C00002766 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00002644 C00002766 | 1 / 1 |
| P22303 | Acetylcholinesterase | Hydrolase | C00002644 C00002766 | 1 / 0 |
| O43570 | Carbonic anhydrase 12 | Lyase | C00002644 C00003794 | 1 / 2 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00002644 C00002766 | 1 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00002644 C00002766 | 0 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00002644 C00002766 | 0 / 0 |
| P08246 | Neutrophil elastase | S1A | C00002644 C00002766 | 2 / 1 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00002644 C00002766 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00002644 C00002766 | 2 / 2 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00002644 C00002766 | 5 / 2 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00003794 C00006935 | 2 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00002644 C00002766 | 0 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00002644 C00003795 | 1 / 1 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00002644 C00002766 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00002644 C00002766 | 2 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00002644 C00002766 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00002644 C00002766 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00002644 C00002766 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00002644 C00002766 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00002644 C00002766 | 1 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00002644 C00002766 | 2 / 2 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00002644 C00002766 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00002644 C00002766 | 0 / 0 |
| P40225 | Thrombopoietin | Unclassified protein | C00002644 C00002766 | 1 / 1 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00002644 C00002766 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00002644 C00002766 | 0 / 0 |
| Q16790 | Carbonic anhydrase 9 | Lyase | C00002644 C00003794 | 0 / 1 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00002644 C00002766 | 1 / 0 |
| P00915 | Carbonic anhydrase 1 | Lyase | C00002644 C00003794 | 0 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00002644 C00002766 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00002644 C00002766 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00002644 C00002766 | 1 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00002644 C00002766 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00002644 C00002766 | 2 / 1 |
| P03956 | Interstitial collagenase | M10A | C00002644 C00002766 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00002644 C00002766 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00002766 C00003794 | 7 / 37 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00002644 C00002766 | 1 / 1 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002644 C00002766 | 1 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00002644 C00002766 | 0 / 0 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00002644 C00006935 | 0 / 0 |
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00002644 C00002766 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00002644 C00002766 | 1 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00002644 C00003794 | 0 / 0 |
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00002644 C00002766 | 0 / 0 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00002644 C00002766 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00002644 C00002766 | 0 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00002644 C00002766 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00002644 C00002766 | 3 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00002644 C00002766 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00002644 C00002766 | 2 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00002644 C00003794 | 5 / 3 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00002644 C00002766 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00002644 C00002766 | 1 / 0 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00000992 C00003794 | 4 / 4 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00002644 C00002766 | 0 / 0 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00002644 C00002766 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00003794 | 4 / 2 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00003794 | 2 / 2 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00002766 | 2 / 0 |
| P51843 | Nuclear receptor subfamily 0 group B member 1 | Nuclear hormone receptor subfamily 0 group B member 1 | C00003794 | 2 / 2 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00002766 | 0 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00002644 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00002766 | 0 / 0 |
| O00519 | Fatty-acid amide hydrolase 1 | Enzyme | C00003794 | 0 / 0 |
| P10145 | Interleukin-8 | Secreted protein | C00002644 | 0 / 0 |
| P08253 | 72 kDa type IV collagenase | M10A | C00002644 | 1 / 3 |
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00003794 | 0 / 0 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00003794 | 2 / 0 |
| Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | C00003794 | 1 / 1 |
| Q04828 | Aldo-keto reductase family 1 member C1 | Enzyme | C00002766 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00003794 | 4 / 2 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00002644 | 0 / 0 |
| P16152 | Carbonyl reductase [NADPH] 1 | Enzyme | C00003794 | 0 / 0 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00002644 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00002644 | 0 / 0 |
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00003794 | 0 / 0 |
| Q8TDS4 | Hydroxycarboxylic acid receptor 2 | Hydroxycarboxylic acid receptor | C00000170 | 0 / 0 |
| P42330 | Aldo-keto reductase family 1 member C3 | Enzyme | C00002766 | 0 / 0 |
| P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00003794 | 1 / 1 |
| P16581 | E-selectin | Adhesion | C00003794 | 0 / 0 |
| Q9ULX7 | Carbonic anhydrase 14 | Lyase | C00002644 | 0 / 0 |
| Q9Y3R4 | Sialidase-2 | Enzyme | C00003794 | 0 / 0 |
| P11216 | Glycogen phosphorylase, brain form | Enzyme | C00002672 | 0 / 0 |
| P23280 | Carbonic anhydrase 6 | Lyase | C00002644 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00003794 | 2 / 3 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00002631 | 0 / 0 |
| Q9GZT9 | Egl nine homolog 1 | Enzyme | C00002644 | 1 / 1 |
| O75828 | Carbonyl reductase [NADPH] 3 | Enzyme | C00003794 | 0 / 0 |
| Q02880 | DNA topoisomerase 2-beta | Isomerase | C00003794 | 0 / 0 |
| Q15078 | Cyclin-dependent kinase 5 activator 1 | REG serine/threonine protein kinase family | C00003794 | 0 / 0 |
| P14151 | L-selectin | Adhesion | C00003794 | 0 / 0 |
| P16109 | P-selectin | Adhesion | C00003794 | 1 / 0 |
| Q00535 | Cyclin-dependent kinase 5 | Cdk5 | C00003794 | 0 / 0 |
| P37059 | Estradiol 17-beta-dehydrogenase 2 | Enzyme | C00003794 | 0 / 0 |
| Q00534 | Cyclin-dependent kinase 6 | CMGC serine/threonine protein kinase family | C00003794 | 1 / 0 |
| P05091 | Aldehyde dehydrogenase, mitochondrial | Oxidoreductase | C00003794 | 1 / 1 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00003794 | 0 / 0 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00006935 | 1 / 0 |
| P52895 | Aldo-keto reductase family 1 member C2 | Enzyme | C00002766 | 1 / 0 |
| P62158 | Calmodulin | Unclassified protein | C00003794 | 1 / 0 |
| P20813 | Cytochrome P450 2B6 | Cytochrome P450 2B6 | C00003794 | 1 / 0 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00003794 | 5 / 1 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00003794 | 0 / 0 |
| P22894 | Neutrophil collagenase | M10A | C00002644 | 0 / 0 |
| P43166 | Carbonic anhydrase 7 | Lyase | C00002644 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00003794 | 3 / 4 |
| P35218 | Carbonic anhydrase 5A, mitochondrial | Lyase | C00002644 | 0 / 0 |
| Q9Y2D0 | Carbonic anhydrase 5B, mitochondrial | Lyase | C00002644 | 0 / 0 |
| P04062 | Glucosylceramidase | Enzyme | C00003795 | 6 / 4 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00003794 | 0 / 0 |
| P22001 | Potassium voltage-gated channel subfamily A member 3 | KCNA, Kv1.x (Shaker) | C00006935 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00002644 | 0 / 0 |
| P07451 | Carbonic anhydrase 3 | Lyase | C00002644 | 0 / 0 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00002644 | 0 / 0 |
| Q04760 | Lactoylglutathione lyase | Enzyme | C00003794 | 0 / 0 |
| P35869 | Aryl hydrocarbon receptor | Transcription Factor | C00003794 | 0 / 0 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00002766 | 0 / 0 |
| P08254 | Stromelysin-1 | M10A | C00002644 | 1 / 0 |
| P22748 | Carbonic anhydrase 4 | Lyase | C00002644 | 1 / 1 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00002644 | 0 / 0 |
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00002766 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00002644 | 0 / 0 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00003794 | 0 / 0 |
| P56937 | 3-keto-steroid reductase | Enzyme | C00003794 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00006935 | 0 / 0 |
| P17516 | Aldo-keto reductase family 1 member C4 | Enzyme | C00002766 | 1 / 0 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000170 | 0 / 0 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00002766 | 0 / 0 |
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00003794 | 3 / 0 |
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00003794 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00002766 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00002766 | 1 / 4 |
| Q9UN88 | Gamma-aminobutyric acid receptor subunit theta | GABA-A theta | C00003794 | 0 / 0 |
| P28472 | Gamma-aminobutyric acid receptor subunit beta-3 | GABA-A beta | C00003794 | 1 / 0 |
| P14867 | Gamma-aminobutyric acid receptor subunit alpha-1 | GABA-A alpha | C00003794 | 1 / 1 |
| P48169 | Gamma-aminobutyric acid receptor subunit alpha-4 | GABA-A alpha | C00003794 | 0 / 0 |
| O14764 | Gamma-aminobutyric acid receptor subunit delta | GABA-A delta | C00003794 | 1 / 1 |
| P31644 | Gamma-aminobutyric acid receptor subunit alpha-5 | GABA-A alpha | C00003794 | 0 / 0 |
| Q99928 | Gamma-aminobutyric acid receptor subunit gamma-3 | GABA-A gamma | C00003794 | 0 / 0 |
| P78334 | Gamma-aminobutyric acid receptor subunit epsilon | GABA-A epsilon | C00003794 | 0 / 0 |
| Q8N1C3 | Gamma-aminobutyric acid receptor subunit gamma-1 | GABA-A gamma | C00003794 | 0 / 0 |
| P34903 | Gamma-aminobutyric acid receptor subunit alpha-3 | GABA-A alpha | C00003794 | 0 / 0 |
| O00591 | Gamma-aminobutyric acid receptor subunit pi | GABA-A pi | C00003794 | 0 / 0 |
| P47870 | Gamma-aminobutyric acid receptor subunit beta-2 | GABA-A beta | C00003794 | 0 / 0 |
| P18507 | Gamma-aminobutyric acid receptor subunit gamma-2 | GABA-A gamma | C00003794 | 4 / 2 |
| P18505 | Gamma-aminobutyric acid receptor subunit beta-1 | GABA-A beta | C00003794 | 0 / 0 |
| Q16445 | Gamma-aminobutyric acid receptor subunit alpha-6 | GABA-A alpha | C00003794 | 0 / 0 |
| P47869 | Gamma-aminobutyric acid receptor subunit alpha-2 | GABA-A alpha | C00003794 | 1 / 0 |
| O95067 | G2/mitotic-specific cyclin-B2 | Other cytosolic protein | C00003794 | 0 / 0 |
| P14635 | G2/mitotic-specific cyclin-B1 | Other cytosolic protein | C00003794 | 0 / 0 |
| P06493 | Cyclin-dependent kinase 1 | Cdc2 | C00003794 | 0 / 0 |
| Q8WWL7 | G2/mitotic-specific cyclin-B3 | Other cytosolic protein | C00003794 | 0 / 0 |
| P49840 | Glycogen synthase kinase-3 alpha | Gsk | C00003794 | 0 / 0 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00003794 | 0 / 0 |
| P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00003794 | 0 / 0 |
| P14061 | Estradiol 17-beta-dehydrogenase 1 | Enzyme | C00003794 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00002766 | 1 / 1 |
115 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 6817 | SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) |
C00000992
C00002644
C00003794
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00002644
C00002766
C00003794
|
| 7412 | VCAM1, CD106, INCAM-100 | vascular cell adhesion molecule 1 |
C00002766
C00003794
|
| 6818 | SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) |
C00000992
C00002644
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00002766
C00003794
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00002766
C00003794
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00002644
C00003794
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002766
C00003794
|
| 331 | XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 | X-linked inhibitor of apoptosis |
C00002766
C00003794
|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00002644
C00002766
|
| 1906 | EDN1, ET1, HDLCQ7, PPET1 | endothelin 1 |
C00002766
C00003794
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00002766
C00003794
|
| 891 | CCNB1, CCNB | cyclin B1 |
C00002766
C00003794
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00002766
C00003794
|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00002766
C00003794
|
| 3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00002766
C00003794
|
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00003794
|
| 3145 | HMBS, PBG-D, PBGD, PORC, UPS | hydroxymethylbilane synthase (EC:2.5.1.61) |
C00002644
|
| 3586 | IL10, CSIF, GVHDS, IL-10, IL10A, TGIF | interleukin 10 |
C00002644
|
| 2623 | GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT | GATA binding protein 1 (globin transcription factor 1) |
C00002644
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00002644
|
| 1728 | NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 | NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) |
C00002644
|
| 6799 | SULT1A2, HAST4, P-PST, ST1A2, STP2, TSPST2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 (EC:2.8.2.1) |
C00002644
|
| 6819 | SULT1C2, ST1C1, ST1C2, SULT1C1, humSULTC2 | sulfotransferase family, cytosolic, 1C, member 2 (EC:2.8.2.-) |
C00002644
|
| 7037 | TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90 | transferrin receptor |
C00002644
|
| 5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00003794
|
| 1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) |
C00002644
|
| 1244 | ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
C00003794
|
| 8714 | ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
C00003794
|
| 10057 | ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
C00003794
|
| 9429 | ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1 | ATP-binding cassette, sub-family G (WHITE), member 2 |
C00003794
|
| 1312 | COMT | catechol-O-methyltransferase (EC:2.1.1.6) |
C00002644
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00003794
|
| 405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator |
C00003794
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00003794
|
| 834 | CASP1, ICE, IL1BC, P45 | caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36) |
C00003794
|
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00003794
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00003794
|
| 6352 | CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP | chemokine (C-C motif) ligand 5 |
C00002644
|
| 6351 | CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 | chemokine (C-C motif) ligand 4 |
C00002644
|
| 1031 | CDKN2C, INK4C, p18, p18-INK4C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
C00003794
|
| 1499 | CTNNB1, CTNNB, MRD19, armadillo | catenin (cadherin-associated protein), beta 1, 88kDa |
C00003794
|
| 1588 | CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM | cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00003794
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00003794
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00003794
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00003794
|
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00003794
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00003794
|
| 6348 | CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 | chemokine (C-C motif) ligand 3 |
C00002644
|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00003794
|
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00003794
|
| 9415 | FADS2, D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13 | fatty acid desaturase 2 (EC:1.14.19.-) |
C00003794
|
| 2203 | FBP1, FBP | fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) |
C00003794
|
| 2353 | FOS, AP-1, C-FOS, p55 | FBJ murine osteosarcoma viral oncogene homolog |
C00003794
|
| 4616 | GADD45B, GADD45BETA, MYD118 | growth arrest and DNA-damage-inducible, beta |
C00003794
|
| 3122 | HLA-DRA, HLA-DRA1, MLRW | major histocompatibility complex, class II, DR alpha |
C00003794
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00003794
|
| 3600 | IL15, IL-15 | interleukin 15 |
C00003794
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00003794
|
| 3554 | IL1R1, CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80 | interleukin 1 receptor, type I |
C00003794
|
| 3565 | IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 | interleukin 4 |
C00003794
|
| 3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00003794
|
| 6356 | CCL11, SCYA11 | chemokine (C-C motif) ligand 11 |
C00002644
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00003794
|
| 5335 | PLCG1, NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1 | phospholipase C, gamma 1 (EC:3.1.4.11) |
C00003794
|
| 5465 | PPARA, NR1C1, PPAR, PPARalpha, hPPAR | peroxisome proliferator-activated receptor alpha |
C00003794
|
| 8000 | PSCA, PRO232 | prostate stem cell antigen |
C00003794
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00003794
|
| 840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00002644
|
| 6309 | SC5D, ERG3, S5DES, SC5DL | sterol-C5-desaturase (EC:1.14.21.6) |
C00003794
|
| 6319 | SCD, FADS5, MSTP008, SCD1, SCDOS | stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) |
C00003794
|
| 2810 | SFN, YWHAS | stratifin |
C00003794
|
| 6783 | SULT1E1, EST, EST-1, ST1E1, STE | sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4) |
C00003794
|
| 29110 | TBK1, NAK, T2K | TANK-binding kinase 1 (EC:2.7.11.1) |
C00003794
|
| 7031 | TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 | trefoil factor 1 |
C00003794
|
| 212 | ALAS2, ALAS-E, ALASE, ANH1, ASB, XLDPP, XLEPP, XLSA | aminolevulinate, delta-, synthase 2 (EC:2.3.1.37) |
C00002644
|
| 8743 | TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL | tumor necrosis factor (ligand) superfamily, member 10 |
C00003794
|
| 7052 | TGM2, G-ALPHA-h, GNAH, TG2, TGC | transglutaminase 2 (EC:2.3.2.13) |
C00000992
|
| 9540 | TP53I3, PIG3 | tumor protein p53 inducible protein 3 |
C00003794
|
| 8626 | TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L | tumor protein p63 |
C00003794
|
| 7161 | TP73, P73 | tumor protein p73 |
C00003794
|
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00003794
|
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00003794
|
| 54578 | UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F | UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) |
C00003794
|
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00003794
|
| 3043 | HBB, CD113t-C, beta-globin | hemoglobin, beta |
C00002644
|
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00003794
|
| 7366 | UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 | UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) |
C00003794
|
| 7402 | UTRN, DMDL, DRP, DRP1 | utrophin |
C00003794
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00000992
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00000992
|
| 9564 | BCAR1, CAS, CAS1, CASS1, CRKAS, P130Cas | breast cancer anti-estrogen resistance 1 |
C00002766
|
| 329 | BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 | baculoviral IAP repeat containing 2 |
C00002766
|
| 330 | BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 | baculoviral IAP repeat containing 3 |
C00002766
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00002766
|
| 898 | CCNE1, CCNE | cyclin E1 |
C00002766
|
| 929 | CD14 | CD14 molecule |
C00002766
|
| 983 | CDK1, CDC2, CDC28A, P34CDC2 | cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) |
C00002766
|
| 1017 | CDK2, p33(CDK2) | cyclin-dependent kinase 2 (EC:2.7.11.22) |
C00002766
|
| 1053 | CEBPE, C/EBP-epsilon, CRP1 | CCAAT/enhancer binding protein (C/EBP), epsilon |
C00002766
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00002766
|
| 3458 | IFNG, IFG, IFI | interferon, gamma |
C00002766
|
| 3606 | IL18, IGIF, IL-18, IL-1g, IL1F4 | interleukin 18 (interferon-gamma-inducing factor) |
C00002766
|
| 3552 | IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1 | interleukin 1, alpha |
C00002766
|
| 3558 | IL2, IL-2, TCGF, lymphokine | interleukin 2 |
C00002766
|
| 3684 | ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6 | integrin, alpha M (complement component 3 receptor 3 subunit) |
C00002766
|
| 4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00002766
|
| 4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00002766
|
| 4791 | NFKB2, H2TF1, LYT-10, LYT10, NF-kB2, p105, p52 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
C00002766
|
| 5320 | PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2 | phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4) |
C00002766
|
| 5747 | PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK | protein tyrosine kinase 2 (EC:2.7.10.2) |
C00002766
|
| 5914 | RARA, NR1B1, RAR | retinoic acid receptor, alpha |
C00002766
|
| 6196 | RPS6KA2, HU-2, MAPKAPK1C, RSK, RSK3, S6K-alpha, S6K-alpha2, p90-RSK3, pp90RSK3 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 (EC:2.7.11.1) |
C00002766
|
| 7042 | TGFB2, LDS4, TGF-beta2 | transforming growth factor, beta 2 |
C00002766
|
| 7299 | TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 | tyrosinase (EC:1.14.18.1) |
C00002766
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (158)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #300018 | 46,xy sex reversal 2; srxy2 |
P51843
|
| #614279 | 46,xy sex reversal 8; srxy8 |
P17516
P52895 |
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #300200 | Adrenal hypoplasia, congenital; ahc |
P51843
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 P47869 |
| #610251 | Alcohol sensitivity, acute |
P05091
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| %606641 | Body mass index; bmi |
P37231
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #114500 | Colorectal cancer; crc |
P18054
P84022 |
| #614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
P22310 |
| #606785 | Crigler-najjar syndrome, type ii |
P22309
P22310 |
| #162800 | Cyclic neutropenia |
P08246
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #607208 | Dravet syndrome |
P18507
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #237500 | Dubin-johnson syndrome; djs |
Q92887
|
| #614546 | Efavirenz, poor metabolism of |
P20813
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #607681 | Epilepsy, childhood absence, susceptibility to, 2; eca2 |
P18507
|
| #612269 | Epilepsy, childhood absence, susceptibility to, 5; eca5 |
P28472
|
| #613060 | Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 |
O14764
|
| #611136 | Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 |
P14867
|
| #609820 | Erythrocytosis, familial, 3; ecyt3 |
Q9GZT9
|
| #133239 | Esophageal cancer |
P04637
P18054 |
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #604233 | Generalized epilepsy with febrile seizures plus, type 1; gefsp1 |
P18507
|
| #611277 | Generalized epilepsy with febrile seizures plus, type 3; gefsp3 |
P18507
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #143500 | Gilbert syndrome |
P22309
P22310 |
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P04626 P37231 |
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #143860 | Hyperchlorhidrosis, isolated |
O43570
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #601626 | Leukemia, acute myeloid; aml |
P36888
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 P04637 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #159900 | Myoclonic dystonia |
P14416
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P32245
P37231 |
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
P38398 |
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
P37840 |
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #604229 | Peters anomaly |
Q16678
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #600852 | Retinitis pigmentosa 17; rp17 |
P22748
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| %612223 | Stature quantitative trait locus 11; stqtl11 |
Q00534
|
| #601367 | Stroke, ischemic |
P16109
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #614916 | Ventricular tachycardia, catecholaminergic polymorphic, 4; cpvt4 |
P62158
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278300 | Xanthinuria, type i |
P47989
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (122)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00783 | Febrile seizures |
O14764
(related)
P18507 (related) |
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H01302 | Hyperchlorhidrosis isolated (HCHLH) |
O43570
(related)
|
| H00021 | Renal cell carcinoma |
O43570
(marker)
P04637 (marker) Q16790 (marker) |
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) P08253 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
P37840 (related) |
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
P11511 (related) |
| H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
| H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) P38398 (related) |
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) P38398 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P35354 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P08253 (related) P14780 (related) P35354 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
P14679 (marker) |
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H01071 | Acute alcohol sensitivity |
P05091
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00808 | Idiopathic generalized epilepsies (IGEs) |
P14867
(related)
P18507 (related) |
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
Q92887 (related) |
| H00527 | Retinitis pigmentosa (RP) |
P22748
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00003 | Acute myeloid leukemia (AML) |
P36888
(related)
Q01196 (related) Q01196 (marker) Q13951 (marker) |
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00552 | Glycerol kinase deficiency (GKD) |
P51843
(related)
|
| H00607 | 46,XY disorders of sex development (Disorders of gonadal development) |
P51843
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00236 | Congenital polycythemia |
Q9GZT9
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
Diseases related to CTD interactions
29 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D011041 | Poisoning |
C00002644
C00002766 |
| D011230 | Precancerous Conditions |
C00003794
C00002766 |
| D020925 | Hypoxia-Ischemia, Brain |
C00002766
|
| D002869 | Chromosome Aberrations |
C00002644
|
| D012640 | Seizures |
C00002644
|
| D000707 | Anaphylaxis |
C00003794
|
| D003110 | Colonic Neoplasms |
C00003794
|
| D007249 | Inflammation |
C00003794
|
| D007680 | Kidney Neoplasms |
C00003794
|
| D008175 | Lung Neoplasms |
C00003794
|
| D048629 | Micronuclei, Chromosome-Defective |
C00002644
|
| D002286 | Carcinoma, Ehrlich Tumor |
C00002766
|
| D005910 | Glioma |
C00002766
|
| D006331 | Heart Diseases |
C00002766
|
| D009784 | Occupational Diseases |
C00002644
|
| D007414 | Intestinal Neoplasms |
C00002766
|
| D007674 | Kidney Diseases |
C00002766
|
| D015473 | Leukemia, Promyelocytic, Acute |
C00002766
|
| D008107 | Liver Diseases |
C00002766
|
| D008113 | Liver Neoplasms |
C00002766
|
| D008545 | Melanoma |
C00002766
|
| D028361 | Mitochondrial Diseases |
C00002766
|
| D009203 | Myocardial Infarction |
C00002766
|
| D009336 | Necrosis |
C00002766
|
| D009361 | Neoplasm Invasiveness |
C00002766
|
| D009362 | Neoplasm Metastasis |
C00002766
|
| D009410 | Nerve Degeneration |
C00002766
|
| D015427 | Reperfusion Injury |
C00002766
|
| D013118 | Spinal Cord Diseases |
C00002766
|