Species

KNApSAcK Entry

Organism name Pseudotsuga wilsoniana
Genus Pseudotsuga
Family Pinaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Pseudotsuga sinensis var. wilsoniana
Linked NCBI taxonomy ID 71408
Linked level varietas

Family

Family in NCBI taxonomy Pinaceae
ID 3318

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Spermatophyta
ID 58024

Metabolite list (22)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000982 External link 512 Naringenin
/ (-)-Naringenin
CHEMBL9352
CHEMBL32571
C005273
57 / 46 / 40 35 / 10 No. 25 No. 14
C00000992 External link 512 Pinocembrin
CHEMBL70518
CHEMBL399910
CHEMBL399249
C016063
18 / 23 / 23 5 / 0 No. 25 No. 14
C00001006 External link 512 Strobopinin
CHEMBL227611
CHEMBL1556958
12 / 5 / 3 No. 25 No. 14
C00014147 External link 512 (2R)-5,4'-Dihydroxy-7-methoxy-6-methylflavanone
No. 25 No. 14
C00008237 External link 512 Poriol
CHEMBL484640
20 / 14 / 14 No. 25 No. 14
C00003672 External link 512 Sitosterol
/ beta-sitosterl
/ (-)-beta-Sitosterol
/ Stigmast-5-en-3beta-ol
CHEMBL221542
CHEMBL1398443
CHEMBL1875388
17 / 19 / 12 No. 53 No. 11
C00029821 External link 512 Sitostenone
/ beta-Sitostenone
/ Stigmast-4-en-3-one
/ Stigmast-4-ene-3-one
CHEMBL66926
No. 53 No. 11
C00003794 External link 512 Chrysin
/ 5,7-Dihydroxyflavone
/ 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one
CHEMBL117
C043561
100 / 89 / 87 69 / 6 No. 76 No. 15
C00020065 External link 512 alpha-Cadinol
/ (-)-alpha-Cadinol
CHEMBL486795
No. 205 No. 38
C00031283 External link 512 Sandaracopimaric acid
/ (-)-Sandaracopimaric acid
CHEMBL513197
CHEMBL1397211
CHEMBL1410398
CHEMBL1735595
C082072
14 / 13 / 7 No. 208 No. 48
C00042455 External link 512 Dehydroabietic acid
CHEMBL12850
C013913
No. 323 No. 41
C00034167 External link 512 Pomiferin A
/ (+)-Pomiferin A
/ 18-Hydroxy-dehydroabietane
CHEMBL12799
No. 359 No. 40
C00042729 External link 512 Meridinol
No. 629 No. 21
C00003028 External link 512 Borneol
/ (+/-)-Borneol
CHEMBL296404
CHEMBL486208
CHEMBL1097205
CHEMBL1968981
8 / 5 / 1 No. 649 No. 35
C00003166 External link 512 Nerolidol
CHEMBL25424
CHEMBL508801
CHEMBL561014
CHEMBL1923157
3 / 3 / 1 No. 726 No. 38
C00002683 External link 512 Vanillin
CHEMBL13883
18 / 8 / 9 No. 1003
C00048973 External link 512 Epijuvabione
/ (+)-Epijuvabione
No. 2112 No. 38
C00048972 External link 512 Epijuvabiol
No. 2112 No. 38
C00049001 External link 512 Methyl 15-hydroxydehydroabietate
No. 2322
C00048957 External link 512 Atlantolone
No. 3871
C00049003 External link 512 Methyl atlantonate
No. 4194 No. 38
C00048953 External link 512 9-Oxo-bis-abola-1,3,5,7E-tetraen-15-oic acid methyl ester
No. 7906

Human Protein / Gene in interactions

158 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000982 C00000992 C00003672 C00003794 C00031283 0 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000982 C00000992 C00003672 C00003794 C00031283 1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000982 C00000992 C00003672 C00003794 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000982 C00000992 C00003672 C00003794 1 / 0
O75496 Geminin Unclassified protein C00000982 C00001006 C00003794 C00031283 0 / 0
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00000982 C00000992 C00003794 C00008237 1 / 2
O00255 Menin Unclassified protein C00000982 C00000992 C00003794 C00008237 2 / 5
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00000992 C00003794 C00008237 C00031283 7 / 3
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000982 C00000992 C00003672 C00003794 0 / 1
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00000982 C00002683 C00003672 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00001006 C00003794 C00031283 2 / 0
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme C00000982 C00002683 C00003794 0 / 0
P10275 Androgen receptor NR3C4 C00000982 C00002683 C00003794 3 / 4
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002683 C00003794 C00031283 0 / 0
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00000982 C00003028 C00003794 3 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00000982 C00000992 C00003794 3 / 3
P06746 DNA polymerase beta Enzyme C00001006 C00003672 C00008237 0 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00000982 C00001006 C00003794 2 / 0
Q9HAW9 UDP-glucuronosyltransferase 1-8 Enzyme C00000982 C00003028 C00003794 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00000992 C00008237 C00031283 0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00000982 C00003028 C00003794 5 / 1
P54855 UDP-glucuronosyltransferase 2B15 Enzyme C00000982 C00003028 C00003794 0 / 0
P08047 Transcription factor Sp1 Unclassified protein C00000992 C00003672 C00003794 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00000992 C00001006 C00008237 0 / 0
P08183 Multidrug resistance protein 1 drug C00000982 C00003672 C00003794 1 / 0
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00000982 C00000992 C00003794 0 / 0
P03372 Estrogen receptor NR3A1 C00000982 C00003672 C00003794 1 / 1
Q9UNA4 DNA polymerase iota Enzyme C00000982 C00001006 C00008237 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00000982 C00001006 C00003794 0 / 3
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00000982 C00000992 C00003794 4 / 4
P37059 Estradiol 17-beta-dehydrogenase 2 Enzyme C00000982 C00003794 0 / 0
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00002683 C00003794 0 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim C00000992 C00003794 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00008237 C00031283 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00000982 C00003794 1 / 1
P62158 Calmodulin Unclassified protein C00000982 C00003794 1 / 0
Q9Y4X1 UDP-glucuronosyltransferase 2A1 Enzyme C00002683 C00003028 0 / 0
P47870 Gamma-aminobutyric acid receptor subunit beta-2 GABA-A beta C00003794 C00031283 0 / 0
P14867 Gamma-aminobutyric acid receptor subunit alpha-1 GABA-A alpha C00003794 C00031283 1 / 1
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00000982 C00003794 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00000992 C00031283 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00002683 C00003794 2 / 2
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein C00000982 C00003794 1 / 1
O75828 Carbonyl reductase [NADPH] 3 Enzyme C00000982 C00003794 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00000992 C00003794 4 / 3
P19224 UDP-glucuronosyltransferase 1-6 Enzyme C00002683 C00003028 0 / 0
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00000982 C00003794 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00003794 C00008237 2 / 3
Q96RI1 Bile acid receptor NR1H4 C00002683 C00003794 0 / 0
Q04760 Lactoylglutathione lyase Enzyme C00000982 C00003794 0 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00000982 C00003794 5 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00002683 C00003794 0 / 0
P14679 Tyrosinase Oxidoreductase C00003672 C00003794 4 / 2
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00000982 C00003794 2 / 2
P04150 Glucocorticoid receptor NR3C1 C00000982 C00003794 0 / 1
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00000982 C00003794 1 / 1
P15121 Aldose reductase Enzyme C00000982 C00003794 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00000992 C00001006 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00008237 C00031283 1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00001006 C00031283 1 / 0
P16152 Carbonyl reductase [NADPH] 1 Enzyme C00000982 C00003794 0 / 0
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00000982 C00003672 0 / 0
P33527 Multidrug resistance-associated protein 1 drugs C00000982 C00003794 0 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme C00002683 C00003028 0 / 0
O00519 Fatty-acid amide hydrolase 1 Enzyme C00002683 C00003794 0 / 0
P14061 Estradiol 17-beta-dehydrogenase 1 Enzyme C00000982 C00003794 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00003672 C00003794 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00000982 C00003166 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00000982 0 / 1
P00915 Carbonic anhydrase 1 Lyase C00003794 0 / 0
P41143 Delta-type opioid receptor Opioid receptor C00000982 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00003794 4 / 2
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00031283 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00001006 0 / 0
P39748 Flap endonuclease 1 Enzyme C00008237 0 / 0
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00008237 0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00003794 0 / 0
Q9NPD5 Solute carrier organic anion transporter family member 1B3 Electrochemical transporter C00000982 1 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein C00001006 0 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00003794 0 / 0
P51843 Nuclear receptor subfamily 0 group B member 1 Nuclear hormone receptor subfamily 0 group B member 1 C00003794 2 / 2
P00734 Prothrombin S1A C00003672 4 / 2
P04278 Sex hormone-binding globulin Secreted protein C00000982 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00003794 1 / 2
P16581 E-selectin Adhesion C00003794 0 / 0
Q9Y3R4 Sialidase-2 Enzyme C00003794 0 / 0
P80404 4-aminobutyrate aminotransferase, mitochondrial Transferase C00002683 1 / 1
P41145 Kappa-type opioid receptor Opioid receptor C00000982 0 / 0
P04745 Alpha-amylase 1 Enzyme C00000982 0 / 0
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00000982 2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00001006 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00003794 0 / 0
Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 Enzyme C00008237 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00003794 0 / 1
Q9HAW7 UDP-glucuronosyltransferase 1-7 Enzyme C00002683 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00008237 1 / 0
P24864 G1/S-specific cyclin-E1 Other cytosolic protein C00000982 0 / 2
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family C00003794 0 / 0
P24941 Cyclin-dependent kinase 2 Cdc2 C00000982 0 / 0
Q00535 Cyclin-dependent kinase 5 Cdk5 C00003794 0 / 0
P16662 UDP-glucuronosyltransferase 2B7 Enzyme C00003028 0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00000982 0 / 0
Q00534 Cyclin-dependent kinase 6 CMGC serine/threonine protein kinase family C00003794 1 / 0
P22303 Acetylcholinesterase Hydrolase C00000982 1 / 0
P35372 Mu-type opioid receptor Opioid receptor C00000982 0 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00003794 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00003166 0 / 0
P14151 L-selectin Adhesion C00003794 0 / 0
P16109 P-selectin Adhesion C00003794 1 / 0
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00002683 0 / 0
P05091 Aldehyde dehydrogenase, mitochondrial Oxidoreductase C00003794 1 / 1
P00918 Carbonic anhydrase 2 Lyase C00003794 1 / 2
P51649 Succinate-semialdehyde dehydrogenase, mitochondrial Oxidoreductase C00002683 1 / 1
P10828 Thyroid hormone receptor beta NR1A2 C00003166 3 / 1
P16473 Thyrotropin receptor Glycohormone receptor C00003672 3 / 2
P20813 Cytochrome P450 2B6 Cytochrome P450 2B6 C00003794 1 / 0
P04062 Glucosylceramidase Enzyme C00000982 6 / 4
P78527 DNA-dependent protein kinase catalytic subunit Atypical serine/threonine protein kinase PIKK subfamily C00002683 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00003672 2 / 0
Q99700 Ataxin-2 Unclassified protein C00003794 1 / 1
O94956 Solute carrier organic anion transporter family member 2B1 Unclassified protein C00000982 0 / 0
P06239 Tyrosine-protein kinase Lck Src C00003794 0 / 1
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00008237 0 / 0
P35869 Aryl hydrocarbon receptor Transcription Factor C00003794 0 / 0
P49888 Estrogen sulfotransferase Enzyme C00000982 0 / 0
P80365 Corticosteroid 11-beta-dehydrogenase isozyme 2 Enzyme C00003672 1 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00008237 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00003794 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00008237 0 / 0
P56937 3-keto-steroid reductase Enzyme C00003794 0 / 0
Q9Y6L6 Solute carrier organic anion transporter family member 1B1 Electrochemical transporter C00000982 1 / 0
Q16637 Survival motor neuron protein Unclassified protein C00003794 4 / 1
Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 Other cytosolic protein C00008237 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00003794 7 / 37
Q9UN88 Gamma-aminobutyric acid receptor subunit theta GABA-A theta C00003794 0 / 0
P28472 Gamma-aminobutyric acid receptor subunit beta-3 GABA-A beta C00003794 1 / 0
P48169 Gamma-aminobutyric acid receptor subunit alpha-4 GABA-A alpha C00003794 0 / 0
O14764 Gamma-aminobutyric acid receptor subunit delta GABA-A delta C00003794 1 / 1
P31644 Gamma-aminobutyric acid receptor subunit alpha-5 GABA-A alpha C00003794 0 / 0
Q99928 Gamma-aminobutyric acid receptor subunit gamma-3 GABA-A gamma C00003794 0 / 0
P78334 Gamma-aminobutyric acid receptor subunit epsilon GABA-A epsilon C00003794 0 / 0
Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1 GABA-A gamma C00003794 0 / 0
P34903 Gamma-aminobutyric acid receptor subunit alpha-3 GABA-A alpha C00003794 0 / 0
O00591 Gamma-aminobutyric acid receptor subunit pi GABA-A pi C00003794 0 / 0
P18507 Gamma-aminobutyric acid receptor subunit gamma-2 GABA-A gamma C00003794 4 / 2
P18505 Gamma-aminobutyric acid receptor subunit beta-1 GABA-A beta C00003794 0 / 0
Q16445 Gamma-aminobutyric acid receptor subunit alpha-6 GABA-A alpha C00003794 0 / 0
P47869 Gamma-aminobutyric acid receptor subunit alpha-2 GABA-A alpha C00003794 1 / 0
Q02410 Amyloid beta A4 precursor protein-binding family A member 1 Unclassified protein C00008237 0 / 0
Q00975 Voltage-dependent N-type calcium channel subunit alpha-1B N-TYPE C00008237 0 / 0
O95067 G2/mitotic-specific cyclin-B2 Other cytosolic protein C00003794 0 / 0
P14635 G2/mitotic-specific cyclin-B1 Other cytosolic protein C00003794 0 / 0
P06493 Cyclin-dependent kinase 1 Cdc2 C00003794 0 / 0
Q8WWL7 G2/mitotic-specific cyclin-B3 Other cytosolic protein C00003794 0 / 0
P49840 Glycogen synthase kinase-3 alpha Gsk C00003794 0 / 0
P27338 Amine oxidase [flavin-containing] B Oxidoreductase C00003794 0 / 0
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00003794 1 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002683 0 / 0

81 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00000982 C00000992 C00003794
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00000982 C00003794
10057 ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 C00000982 C00003794
196 AHR, bHLHe76 aryl hydrocarbon receptor C00000982 C00003794
54600 UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) C00000982 C00003794
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00000982 C00003794
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00000982 C00003794
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00000982 C00003794
405 ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 aryl hydrocarbon receptor nuclear translocator C00000982 C00003794
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00000982 C00003794
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00000982 C00003794
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00000982 C00003794
1588 CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) C00000982 C00003794
7366 UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) C00000982 C00003794
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00000982 C00003794
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00000982 C00003794
1559 CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00000982 C00003794
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00000982 C00003794
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 estrogen receptor 1 C00000982 C00003794
2100 ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 estrogen receptor 2 (ER beta) C00000982 C00003794
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00000982 C00003794
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00000982 C00003794
54658 UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) C00000982 C00003794
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00000982 C00003794
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00000982 C00003794
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00000982 C00003794
6818 SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1) C00000982 C00000992
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00003794
6566 SLC16A1, HHF7, MCT, MCT1 solute carrier family 16 (monocarboxylate transporter), member 1 C00000982
5444 PON1, ESA, MVCD5, PON paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) C00000982
3757 KCNH2, ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1 potassium voltage-gated channel, subfamily H (eag-related), member 2 C00000982
249 ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) C00000982
8644 AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) C00000982
1645 AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) C00000982
10257 ABCC4, EST170205, MOAT-B, MOATB, MRP4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 C00000982
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00000992
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00000992
7052 TGM2, G-ALPHA-h, GNAH, TG2, TGC transglutaminase 2 (EC:2.3.2.13) C00000992
5243 ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) C00003794
1244 ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP ATP-binding cassette, sub-family C (CFTR/MRP), member 2 C00003794
8714 ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 C00003794
9429 ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1 ATP-binding cassette, sub-family G (WHITE), member 2 C00003794
834 CASP1, ICE, IL1BC, P45 caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36) C00003794
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00003794
891 CCNB1, CCNB cyclin B1 C00003794
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00003794
1031 CDKN2C, INK4C, p18, p18-INK4C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) C00003794
1499 CTNNB1, CTNNB, MRD19, armadillo catenin (cadherin-associated protein), beta 1, 88kDa C00003794
1906 EDN1, ET1, HDLCQ7, PPET1 endothelin 1 C00003794
9415 FADS2, D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13 fatty acid desaturase 2 (EC:1.14.19.-) C00003794
2203 FBP1, FBP fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) C00003794
2353 FOS, AP-1, C-FOS, p55 FBJ murine osteosarcoma viral oncogene homolog C00003794
4616 GADD45B, GADD45BETA, MYD118 growth arrest and DNA-damage-inducible, beta C00003794
3122 HLA-DRA, HLA-DRA1, MLRW major histocompatibility complex, class II, DR alpha C00003794
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00003794
3600 IL15, IL-15 interleukin 15 C00003794
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00003794
3554 IL1R1, CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80 interleukin 1 receptor, type I C00003794
3565 IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 interleukin 4 C00003794
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6 interleukin 6 (interferon, beta 2) C00003794
6513 SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED solute carrier family 2 (facilitated glucose transporter), member 1 C00000982
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00003794
5335 PLCG1, NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1 phospholipase C, gamma 1 (EC:3.1.4.11) C00003794
5465 PPARA, NR1C1, PPAR, PPARalpha, hPPAR peroxisome proliferator-activated receptor alpha C00003794
8000 PSCA, PRO232 prostate stem cell antigen C00003794
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00003794
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00003794
6309 SC5D, ERG3, S5DES, SC5DL sterol-C5-desaturase (EC:1.14.21.6) C00003794
6319 SCD, FADS5, MSTP008, SCD1, SCDOS stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) C00003794
2810 SFN, YWHAS stratifin C00003794
6783 SULT1E1, EST, EST-1, ST1E1, STE sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4) C00003794
29110 TBK1, NAK, T2K TANK-binding kinase 1 (EC:2.7.11.1) C00003794
7031 TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 trefoil factor 1 C00003794
8743 TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL tumor necrosis factor (ligand) superfamily, member 10 C00003794
9540 TP53I3, PIG3 tumor protein p53 inducible protein 3 C00003794
8626 TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L tumor protein p63 C00003794
7161 TP73, P73 tumor protein p73 C00003794
54578 UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) C00003794
7402 UTRN, DMDL, DRP, DRP1 utrophin C00003794
7412 VCAM1, CD106, INCAM-100 vascular cell adhesion molecule 1 C00003794
331 XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 X-linked inhibitor of apoptosis C00003794

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (114)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#300018 46,xy sex reversal 2; srxy2 P51843
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#300200 Adrenal hypoplasia, congenital; ahc P51843
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#103780 Alcohol dependence P47869
#610251 Alcohol sensitivity, acute P05091
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#218030 Apparent mineralocorticoid excess; ame P80365
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#614490 Blood group, junior system; jr Q9UNQ0
%606641 Body mass index; bmi P37231
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#300615 Brunner syndrome P21397
#609338 Carotid intimal medial thickness 1 P37231
#114500 Colorectal cancer; crc P18054
P84022
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#119900 Digital clubbing, isolated congenital P15428
#607208 Dravet syndrome P18507
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#237500 Dubin-johnson syndrome; djs Q92887
#614546 Efavirenz, poor metabolism of P20813
#607681 Epilepsy, childhood absence, susceptibility to, 2; eca2 P18507
#612269 Epilepsy, childhood absence, susceptibility to, 5; eca5 P28472
#613060 Epilepsy, idiopathic generalized, susceptibility to, 10; eig10 O14764
#611136 Epilepsy, juvenile myoclonic, susceptibility to, 5; ejm5 P14867
#133239 Esophageal cancer P04637
P18054
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#613163 Gaba-transaminase deficiency P80404
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#604233 Generalized epilepsy with febrile seizures plus, type 1; gefsp1 P18507
#611277 Generalized epilepsy with febrile seizures plus, type 3; gefsp3 P18507
#143500 Gilbert syndrome P22309
P22310
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#137800 Glioma susceptibility 1; glm1 O75874
P37231
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#237450 Hyperbilirubinemia, rotor type; hblrr Q9NPD5
Q9Y6L6
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#143860 Hyperchlorhidrosis, isolated O43570
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#612244 Inflammatory bowel disease 13; ibd13 P08183
#601626 Leukemia, acute myeloid; aml P36888
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#211980 Lung cancer P04637
#174800 Mccune-albright syndrome; mas P63092
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#601665 Obesity P37231
#166350 Osseous heteroplasia, progressive; poh P63092
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#604229 Peters anomaly Q16678
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
%612223 Stature quantitative trait locus 11; stqtl11 Q00534
#601367 Stroke, ischemic P00734
P16109
#271980 Succinic semialdehyde dehydrogenase deficiency; ssadhd P51649
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188050 Thrombophilia due to thrombin defect; thph1 P00734
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#614916 Ventricular tachycardia, catecholaminergic polymorphic, 4; cpvt4 P62158
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253
#112100 Yt blood group antigen P22303

KEGG DISEASE (100)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00783 Febrile seizures O14764 (related)
P18507 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
P04637 (marker)
Q16790 (marker)
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00026 Endometrial Cancer P03372 (marker)
P04637 (related)
Q92731 (marker)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
P11511 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P04637 (related)
P24864 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00027 Ovarian cancer P04637 (related)
P38398 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
P38398 (related)
H00032 Thyroid cancer P04637 (related)
P37231 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
P14679 (marker)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
P35354 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
P24864 (related)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H01071 Acute alcohol sensitivity P05091 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00794 Aromatase excess syndrome P11511 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00808 Idiopathic generalized epilepsies (IGEs) P14867 (related)
P18507 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00548 Brunner syndrome P21397 (related)
H00208 Hyperbilirubinemia P22309 (related)
Q92887 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)
H00192 Xanthinuria P47989 (related)
H00835 Succinic semialdehyde dehydrogenase (SSADH) deficiency P51649 (related)
H00552 Glycerol kinase deficiency (GKD) P51843 (related)
H00607 46,XY disorders of sex development (Disorders of gonadal development) P51843 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00259 Apparent mineralocorticoid excess syndrome P80365 (related)
H01257 GABA-transaminase deficiency P80404 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

16 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D000647 Amnesia C00000982
D001932 Brain Neoplasms C00000982
D009202 Cardiomyopathies C00000982
D056486 Drug-Induced Liver Injury C00000982
D064420 Drug-Related Side Effects and Adverse Reactions C00000982
D007674 Kidney Diseases C00000982
D008106 Liver Cirrhosis, Experimental C00000982
D008107 Liver Diseases C00000982
D009369 Neoplasms C00000982
D009374 Neoplasms, Experimental C00000982
D000707 Anaphylaxis C00003794
D003110 Colonic Neoplasms C00003794
D007249 Inflammation C00003794
D007680 Kidney Neoplasms C00003794
D008175 Lung Neoplasms C00003794
D011230 Precancerous Conditions C00003794