PCIDB

KNApSAcK Metabolite C00008459

Index

Metabolite

Species

Human Protein
/ Gene in interactions

Related Diseases

Metabolite

KNApSAcK Entry

id	C00008459
Name	Glabrol
CAS RN	59870-65-4
Standard InChI	InChI=1S/C25H28O4/c1-15(2)5-7-17-13-18(8-11-21(17)26)24-14-23(28)20-10-12-22(27)19(25(20)29-24)9-6-16(3)4/h5-6,8,10-13,24,26-27H,7,9,14H2,1-4H3
Standard InChI (Main Layer)	InChI=1S/C25H28O4/c1-15(2)5-7-17-13-18(8-11-21(17)26)24-14-23(28)20-10-12-22(27)19(25(20)29-24)9-6-16(3)4/h5-6,8,10-13,24,26-27H,7,9,14H2,1-4H3

Cluster

Phytochemical cluster	No. 14
KCF-S cluster	No. 19

Link

ChEMBL

By standard InChI
By standard InChI Main Layer	CHEMBL462721

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name	count
rosids	7

Family

family name	count
Fabaceae	7

List (7)

* NCBI

KNApSAcK organism	*ID	*family	*plant class	*kingdom
Euchresta horsfeldii	53878	Fabaceae	rosids	Viridiplantae
Euchresta japonica	256639	Fabaceae	rosids	Viridiplantae
Glycyrrhiza glabra	49827	Fabaceae	rosids	Viridiplantae
Glycyrrhiza glara	46347	Fabaceae	rosids	Viridiplantae
Glycyrrhiza inflata	74614	Fabaceae	rosids	Viridiplantae
Sophora alopecuroides	200492	Fabaceae	rosids	Viridiplantae
Sophora prostrata	76398	Fabaceae	rosids	Viridiplantae

Human Protein / Gene in interaction

7 ChEMBL Protein in interactions

accession	description	class description	compound	assay ID (# of activities)	# of diseases (OMIM / KEGG)
Q99700	Ataxin-2	Unclassified protein	CHEMBL462721	CHEMBL2114784 (1)	1 / 1
P37840	Alpha-synuclein	Unclassified protein	CHEMBL462721	CHEMBL2354282 (1)	4 / 2
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	CHEMBL462721	CHEMBL1794584 (1)	2 / 0
O75496	Geminin	Unclassified protein	CHEMBL462721	CHEMBL2114843 (1) CHEMBL2114780 (1)	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	CHEMBL462721	CHEMBL1068398 (1)	5 / 3
O75164	Lysine-specific demethylase 4A	Enzyme	CHEMBL462721	CHEMBL1737991 (1)	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	CHEMBL462721	CHEMBL1964002 (1)	1 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM	preferred title	UniProt
%606641	Body mass index; bmi	P37231
#609338	Carotid intimal medial thickness 1	P37231
#114500	Colorectal cancer; crc	P84022
#127750	Dementia, lewy body; dlb	P37840
#137800	Glioma susceptibility 1; glm1	O75874 P37231
#604367	Lipodystrophy, familial partial, type 3; fpld3	P37231
#613795	Loeys-dietz syndrome, type 3; lds3	P84022
#601665	Obesity	P37231
#168601	Parkinson disease 1, autosomal dominant; park1	P37840
#605543	Parkinson disease 4, autosomal dominant; park4	P37840
#168600	Parkinson disease, late-onset; pd	P37840
#183090	Spinocerebellar ataxia 2; sca2	Q99700

KEGG DISEASE (6)

KEGG	disease name	UniProt
H00032	Thyroid cancer	P37231 (related)
H00409	Type II diabetes mellitus	P37231 (related)
H00420	Familial partial lipodystrophy (FPL)	P37231 (related)
H00057	Parkinson's disease (PD)	P37840 (related)
H00066	Lewy body dementia (LBD)	P37840 (related)
H00063	Spinocerebellar ataxia (SCA)	Q99700 (related)