| Organism name | Euchresta horsfeldii |
|---|---|
| Genus | Euchresta |
| Family | Fabaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Euchresta |
|---|---|
| Linked NCBI taxonomy ID | 53878 |
| Linked level | genus |
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | rosids |
|---|---|
| ID | 71275 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00009943
|
Euchrenone b8
|
No. 18 | No. 15 |
|
||||
|
C00009948
|
Euchrenone b9
|
No. 18 | No. 15 |
|
||||
|
C00009944
|
Euchrenone b6
|
No. 18 | No. 15 |
|
||||
|
C00009949
|
Euchrenone b7
|
No. 18 | No. 15 |
|
||||
|
C00008466
|
Kushenol E
/ Flemiphilippinin D |
C070774
|
No. 19 | No. 14 |
|
|||
|
C00008462
|
Euchrenone a8
|
No. 19 | No. 14 |
|
||||
|
C00008459
|
Glabrol
|
CHEMBL462721
|
7 / 12 / 6 | No. 19 | No. 14 |
|
||
|
C00008452
|
Euchrenone a7
/ (2S)-Euchrenone a7 / (-)-(2S)-Euchrenone a7 |
CHEMBL457686
|
1 / 2 / 2 | No. 28 | No. 14 |
|
||
|
C00008463
|
Euchrenone a9
|
CHEMBL550385
|
No. 39 |
|
||||
|
C00009950
|
Euchrenone b10
/ 8-Prenylerythrinin C |
CHEMBL2159049
|
C109428
|
1 / 0 / 0 | No. 47 | No. 15 |
|
|
|
C00002227
|
Matrine
/ (+)-Matrine |
CHEMBL204860
CHEMBL383443 CHEMBL525227 CHEMBL1396816 CHEMBL1733145 CHEMBL1824581 |
C034244
|
5 / 3 / 7 | 4 / 5 | No. 85 | No. 3 |
|
|
C00010011
|
Sophoracarpan B
/ 6-Methoxymaackiain / (6R,6aS,11aR)-3-Hydroxy-6-methoxy-8,9-methylenedioxypterocarpan |
No. 1655 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00009950 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00008459 | 1 / 1 |
| P37840 | Alpha-synuclein | Unclassified protein | C00008459 | 4 / 2 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00002227 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002227 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00008459 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00008459 | 0 / 0 |
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00008452 | 2 / 2 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00008459 | 5 / 3 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00002227 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00008459 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00008459 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00002227 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002227 | 1 / 2 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00002227
|
| 4893 | NRAS, ALPS4, N-ras, NRAS1, NS6 | neuroblastoma RAS viral (v-ras) oncogene homolog |
C00002227
|
| 7150 | TOP1, TOPI | topoisomerase (DNA) I (EC:5.99.1.2) |
C00002227
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00002227
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #613546 | Aromatase deficiency |
P11511
|
| #139300 | Aromatase excess syndrome; aexs |
P11511
|
| %606641 | Body mass index; bmi |
P37231
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P37231 |
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #601665 | Obesity |
P37231
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P11511
(related)
|
| H00794 | Aromatase excess syndrome |
P11511
(related)
|
| H00032 | Thyroid cancer |
P37231
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P37231
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|