Sophora alopecuroides

• Index
• Plant Species
• Metabolite list (26)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Sophora alopecuroides
Genus	Sophora
Family	Fabaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Sophora alopecuroides
Linked NCBI taxonomy ID	200492
Linked level	species

Family

Family in NCBI taxonomy	Fabaceae
ID	3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (26)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00008364	Norkurarinone / Sophoraflavanone G	CHEMBL243148 CHEMBL479477	C064849	3 / 2 / 2		No. 19	No. 14
C00008335	Isokurarinone					No. 19	No. 14
C00014193	Alopecurone G / 7,4'-Dihydroxy-8-lavandulyl-2'-methoxyflavanone					No. 19	No. 14
C00008459	Glabrol	CHEMBL462721		7 / 12 / 6		No. 19	No. 14
C00008334	Kushenol F					No. 19	No. 14
C00008197	Isobavachin	CHEMBL491534	C468753		2 / 0	No. 28	No. 14
C00002227	Matrine / (+)-Matrine	CHEMBL204860 CHEMBL383443 CHEMBL525227 CHEMBL1396816 CHEMBL1733145 CHEMBL1824581	C034244	5 / 3 / 7	4 / 5	No. 85	No. 3
C00026311	14beta-Hydroxymatrine / (-)-14beta-Hydroxymatrine					No. 85	No. 3
C00007757	Sophoridine / (-)-Sophoridine	CHEMBL204860 CHEMBL383443 CHEMBL525227 CHEMBL1396816 CHEMBL1733145 CHEMBL1824581		5 / 3 / 7		No. 85	No. 3
C00007138	Ammothamnidin					No. 190	No. 13
C00002212	Baptifoline / (-)-Baptifoline		C106940			No. 384	No. 3
C00002235	Sophoramine		C055681			No. 384	No. 3
C00026319	7alpha-Hydroxysophoramine					No. 384	No. 3
C00014268	Alopecurone D					No. 669
C00014270	Alopecurone F					No. 669
C00014269	Alopecurone E					No. 669
C00014265	Alopecurone A / Alopecurone I					No. 669
C00014267	Alopecurone C / Alopecurone III					No. 669
C00014266	Alopecurone B / Alopecurone II					No. 669
C00023309	Lemannine / Lehmannine / (+)-Lehmannine	CHEMBL205311				No. 1721
C00026307	12beta-Hydroxysophocarpine	CHEMBL441175				No. 1721
C00007759	Sophocarpine / (-)-Sophocarpine	CHEMBL377725 CHEMBL380909	C035933		0 / 1	No. 1721
C00001183	Fumaric acid	CHEMBL503160 CHEMBL539648	C032005	17 / 14 / 46	0 / 1	No. 3766
C00002205	Aloperine		C062701			No. 4113
C00007785	11,12-Dehydroaloperine					No. 6990
C00001198	Oxalic acid	CHEMBL146755	D019815	2 / 0 / 0	1 / 6	No. 7540

Human Protein / Gene in interactions

32 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00001183 C00008459	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002227 C00007757	1 / 2
O00255	Menin	Unclassified protein	C00002227 C00007757	2 / 5
O75164	Lysine-specific demethylase 4A	Enzyme	C00001183 C00008459	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00002227 C00007757	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002227 C00007757	0 / 0
P11387	DNA topoisomerase 1	Isomerase	C00002227 C00007757	0 / 0
P13866	Sodium/glucose cotransporter 1	Glucose	C00008364	1 / 1
P37840	Alpha-synuclein	Unclassified protein	C00008459	4 / 2
P16473	Thyrotropin receptor	Glycohormone receptor	C00001183	3 / 2
P00918	Carbonic anhydrase 2	Lyase	C00001183	1 / 2
Q9GZT9	Egl nine homolog 1	Enzyme	C00001183	1 / 1
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00001183	0 / 0
Q8TDS4	Hydroxycarboxylic acid receptor 2	Hydroxycarboxylic acid receptor	C00001183	0 / 0
Q16798	NADP-dependent malic enzyme, mitochondrial	Enzyme	C00001183	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00008459	2 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00001183	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00001183	0 / 0
P11308	Transcriptional regulator ERG	Unclassified protein	C00001183	1 / 2
P83916	Chromobox protein homolog 1	Unclassified protein	C00001183	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00008459	5 / 3
P12931	Proto-oncogene tyrosine-protein kinase Src	Src	C00001198	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00008459	1 / 1
P56817	Beta-secretase 1	A1A	C00008364	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001183	0 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00001198	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00001183	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00001183	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00008459	1 / 0
P31639	Sodium/glucose cotransporter 2	Glucose	C00008364	1 / 1
P04637	Cellular tumor antigen p53	Transcription Factor	C00001183	7 / 37
Q9C0B1	Alpha-ketoglutarate-dependent dioxygenase FTO	Unclassified protein	C00001183	1 / 2

7 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00002227
4893	NRAS, ALPS4, N-ras, NRAS1, NS6	neuroblastoma RAS viral (v-ras) oncogene homolog	C00002227
7150	TOP1, TOPI	topoisomerase (DNA) I (EC:5.99.1.2)	C00002227
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00002227
5241	PGR, NR3C3, PR	progesterone receptor	C00008197
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00008197
26762	HAVCR1, HAVCR, HAVCR-1, KIM-1, KIM1, TIM, TIM-1, TIM1, TIMD-1, TIMD1	hepatitis A virus cellular receptor 1	C00001198

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions