Species

KNApSAcK Entry

Organism name Euchresta japonica
Genus Euchresta
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Euchresta japonica
Linked NCBI taxonomy ID 256639
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (33)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00009941 External link 512 Euchrenone b5
/ 5,7,2'-Trihydroxy-4',5'-methylenedioxy-6,8-diprenylisoflavone
No. 14 No. 15
C00019413 External link 512 Euchretin F
No. 14 No. 15
C00019401 External link 512 Euchrenone b15
/ 5,7,4'-Trihydroxy-2'-methoxy-6,8-diprenylisoflavone
No. 14 No. 15
C00019400 External link 512 Euchrenone b14
/ 5,7,4'-Trihydroxy-2'-methoxy-6,8,3-triprenylisoflavone
No. 14 No. 15
C00009942 External link 512 Euchrenone b4
/ 5,7-Dihydroxy-2'-methoxy-4',5'-methylenedioxy-6,8-diprenylisoflavone
No. 14 No. 15
C00010071 External link 512 Euchretin C
/ 5,7,4',5'-Tetrahydroxy-6,8,3'-triprenylcoumaronochromone
No. 14 No. 15
C00009516 External link 512 6,8-Diprenylgenistein
/ 8-(gamma,gamma-Dimethylallyl)wighteone
/ 5,7,4'-Trihydroxy-6,8-diprenylisoflavone
CHEMBL494252
12 / 14 / 11 No. 14 No. 15
C00009952 External link 512 Euchrenone b2
/ 5,7,2',4'-Tetrahydroxy-6,8,3'-triprenylisoflavone
No. 14 No. 15
C00009951 External link 512 Euchrenone b1
/ 5,7,4'-Trihydroxy-6,8,3'-triprenylisoflavone
No. 14 No. 15
C00010069 External link 512 Euchretin B
No. 14 No. 15
C00019170 External link 512 Euchretin G
No. 18 No. 15
C00019414 External link 512 Euchretin H
No. 18 No. 15
C00009947 External link 512 Euchrenone b3
/ 5-Hydroxy-2'-methoxy-4',5'-methylenedioxy-6-prenyl-6'',6''-dimethylpyrano[2'',3'':7,8]isoflavone
No. 18 No. 15
C00008622 External link 512 Lespedezaflavanone C
CHEMBL463256
1 / 2 / 2 No. 19 No. 14
C00008266 External link 512 Euchrestaflavanone A
CHEMBL256340
No. 19 No. 14
C00008459 External link 512 Glabrol
CHEMBL462721
7 / 12 / 6 No. 19 No. 14
C00008471 External link 512 Euchrenone a11
No. 39
C00008331 External link 512 Euchrestaflavanone C
No. 39
C00008470 External link 512 Euchrenone a4
No. 39
C00008461 External link 512 Euchrenone a2
No. 39
C00008472 External link 512 Euchrenone a12
No. 39
C00008474 External link 512 Euchrenone a6
CHEMBL559832
No. 39
C00010072 External link 512 Euchretin A
No. 44
C00019402 External link 512 Euchrenone b16
/ 5,2',4'-Trihydroxy-6,3'-diprenyl-6'',6''-dimethylpyrano[2'',3'':7,8]isoflavone
No. 44
C00019399 External link 512 Euchrenone b13
/ 5,4'-Dihydroxy-2'-methoxy-6,3'-diprenyl-6'',6''-dimethylpyrano[2'',3'':7,8]isoflavone
No. 44
C00019397 External link 512 Euchrenone b11
/ 5,5'-Dihydroxy-2'-methoxy-6-prenyl-(2'',3'':7,8),(2''',3''':4',3')-bis(6,6-dimethylpyrano)isoflavone
No. 44
C00019398 External link 512 Euchrenone b12
/ 5,4'-Dihydroxy-2'-methoxy-8,3'-diprenyl-6'',6''-dimethylpyrano[2'',3'':7,6]isoflavone
No. 44
C00009950 External link 512 Euchrenone b10
/ 8-Prenylerythrinin C
CHEMBL2159049
C109428
1 / 0 / 0 No. 47 No. 15
C00008269 External link 512 Amorilin
CHEMBL561642
No. 170 No. 14
C00007092 External link 512 2,4,2'-Trihydroxy-6'',6''-dimethyl-3'-prenylpyrano[2'',3'':4',5']chalcone
No. 186
C00002216 External link 512 Caulophylline
/ N-Methylcytisine
/ (-)-N-Methylcytisine
CHEMBL66191
CHEMBL1085045
C034245
No. 376 No. 3
C00010186 External link 512 Trifolirhizin
/ Sophojaponicin B1
/ (-)-Maackiain 3-O-glucoside
CHEMBL454878
No. 557 No. 15
C00008460 External link 512 Euchrenone a1
No. 881

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00008459 C00009516 1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00008459 C00009516 1 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00008459 C00009516 0 / 0
O75496 Geminin Unclassified protein C00008459 C00009516 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00008459 C00009516 2 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00008459 5 / 3
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00009516 0 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00008622 2 / 2
P37840 Alpha-synuclein Unclassified protein C00008459 4 / 2
P28482 Mitogen-activated protein kinase 1 Erk C00009516 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00009516 0 / 0
P04062 Glucosylceramidase Enzyme C00009516 6 / 4
P10636 Microtubule-associated protein tau Unclassified protein C00009516 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00009516 0 / 0
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00009950 0 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00009516 0 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (23)

OMIM preferred title UniProt
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#114500 Colorectal cancer; crc P84022
#127750 Dementia, lewy body; dlb P37840
#600274 Frontotemporal dementia; ftd P10636
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#137800 Glioma susceptibility 1; glm1 O75874
P37231
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#601665 Obesity P37231
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P04062
P37840
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (17)

KEGG name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00066 Lewy body dementia (LBD) P04062 (related)
P37840 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P11511 (related)
H00794 Aromatase excess syndrome P11511 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)