PCIDB

KNApSAcK Metabolite C00008805

Metabolite

KNApSAcK Entry

id C00008805
Name Epiafzelechin
CAS RN 24808-04-6
Standard InChI InChI=1S/C15H14O5/c16-9-3-1-8(2-4-9)15-13(19)7-11-12(18)5-10(17)6-14(11)20-15/h1-6,13,15-19H,7H2/t13-,15-/m1/s1
Standard InChI (Main Layer) InChI=1S/C15H14O5/c16-9-3-1-8(2-4-9)15-13(19)7-11-12(18)5-10(17)6-14(11)20-15/h1-6,13,15-19H,7H2

Cluster

Phytochemical cluster No. 14
KCF-S cluster No. 52

Link

ChEMBL

By standard InChI CHEMBL159303
By standard InChI Main Layer CHEMBL159303 CHEMBL1326092

KEGG

By LinkDB C12128

CTD

By CAS RN

Human Protein / Gene in interaction

7 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P35354 Prostaglandin G/H synthase 2 Oxidoreductase CHEMBL159303 CHEMBL1020816 (1)
0 / 3
P23219 Prostaglandin G/H synthase 1 Oxidoreductase CHEMBL159303 CHEMBL1020815 (1) CHEMBL1008496 (1)
0 / 0
Q9UM73 ALK tyrosine kinase receptor TKL serine/threonine protein kinase STKR type 1 subfamily CHEMBL1326092 CHEMBL1781229 (1)
1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 CHEMBL1326092 CHEMBL1614108 (1) CHEMBL1613886 (1)
0 / 1
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL1326092 CHEMBL1794536 (1)
0 / 0
O00255 Menin Unclassified protein CHEMBL1326092 CHEMBL1614257 (1) CHEMBL1614531 (1)
2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme CHEMBL1326092 CHEMBL1614257 (1) CHEMBL1614531 (1)
1 / 3

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613014 Neuroblastoma, susceptibility to, 3; nblst3 Q9UM73

KEGG DISEASE (12)

KEGG disease name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00014 Non-small cell lung cancer Q9UM73 (related)