Xanthoceras sorbifolia

• Index
• Plant Species
• Metabolite list (11)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Xanthoceras sorbifolia
Genus	Xanthoceras
Family	Sapindaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Xanthoceras sorbifolium
Linked NCBI taxonomy ID	99658
Linked level	species

Family

Family in NCBI taxonomy	Xanthoceraceae
ID	910344

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (11)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001071	Myricetin	CHEMBL164	C040015	78 / 70 / 56	39 / 2	No. 3	No. 15
C00040672	Xanifolia Y8	CHEMBL1094358		2 / 0 / 0		No. 4	No. 51
C00040671	Xanifolia Y10	CHEMBL1094675		2 / 0 / 0		No. 4	No. 51
C00019064	Oleanolic acid / Astrantiagenin C / Virgaureagenin B / 3beta-Hydroxyolean-12-en-28-oic acid	CHEMBL56615 CHEMBL168 CHEMBL180553 CHEMBL365375 CHEMBL486382 CHEMBL1413646 CHEMBL1436454	D009828	30 / 8 / 12	21 / 15	No. 13	No. 51
C00000982	Naringenin / (-)-Naringenin	CHEMBL9352 CHEMBL32571	C005273	57 / 46 / 40	35 / 10	No. 25	No. 14
C00000938	Ampelopsin / Dihydromyricetin / (2R,3R)-3,5,7,3',4',5'-Hexahydroxyflavanone	CHEMBL2048508	C106407	6 / 5 / 4	1 / 0	No. 42	No. 14
C00000677	Distylin / Dihydroquercetin / (2R,3R)-Taxifolin	CHEMBL66 CHEMBL9249 CHEMBL337309 CHEMBL1492383	C003377	65 / 41 / 37	29 / 1	No. 42	No. 14
C00000956	(-)-Epicatechin	CHEMBL80941 CHEMBL311498 CHEMBL129482 CHEMBL200715 CHEMBL206452 CHEMBL583912		85 / 58 / 54		No. 52	No. 14
C00008818	Epigallocatechin / (-)-Epigallocatechin	CHEMBL47386 CHEMBL125743 CHEMBL130415 CHEMBL264167 CHEMBL404845		26 / 17 / 29		No. 52	No. 14
C00008805	Epiafzelechin	CHEMBL159303 CHEMBL1326092		7 / 4 / 12		No. 52	No. 14
C00046576	24-Methylenecycloartan-3-ol / (+)-24-Methylenecycloartan-3-ol					No. 129	No. 11

Human Protein / Gene in interactions

181 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000956 C00000982 C00001071 C00008805 C00008818 C00019064	0 / 3
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00000677 C00000956 C00000982 C00001071 C00008805	1 / 2
Q9UBT6	DNA polymerase kappa	Enzyme	C00000677 C00000956 C00001071 C00008805 C00008818	0 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00000677 C00000956 C00000982 C00001071 C00008818	1 / 1
O00255	Menin	Unclassified protein	C00000677 C00000956 C00000982 C00001071 C00008805	2 / 5
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000677 C00000956 C00000982 C00001071 C00008818	3 / 3
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00000677 C00000956 C00001071 C00008818 C00019064	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00000677 C00000956 C00000982 C00001071 C00019064	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000677 C00000956 C00000982 C00001071 C00008805	0 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000677 C00000956 C00000982 C00001071	1 / 1
P35372	Mu-type opioid receptor	Opioid receptor	C00000677 C00000956 C00000982 C00008818	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00000677 C00000956 C00001071 C00008818	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000677 C00000956 C00000982 C00001071	0 / 1
P11388	DNA topoisomerase 2-alpha	Isomerase	C00000956 C00001071 C00040671 C00040672	0 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000956 C00008805 C00008818 C00019064	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000677 C00000956 C00000982 C00008818	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00000677 C00000956 C00001071 C00008818	2 / 2
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00000677 C00000956 C00001071 C00008818	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00000677 C00000956 C00001071 C00008818	4 / 3
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000677 C00000956 C00000982 C00001071	0 / 0
P06746	DNA polymerase beta	Enzyme	C00000677 C00000956 C00001071 C00019064	0 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000677 C00000956 C00000982 C00008818	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000677 C00000956 C00001071 C00008818	0 / 0
Q01196	Runt-related transcription factor 1	Unclassified protein	C00000677 C00001071 C00008818 C00019064	1 / 4
Q13951	Core-binding factor subunit beta	Unclassified protein	C00000677 C00001071 C00008818 C00019064	0 / 1
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00000956 C00000982 C00001071 C00008818	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00000956 C00000982 C00001071 C00008818	1 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000677 C00000956 C00000982 C00001071	1 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00000677 C00000956 C00001071	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00000677 C00000956 C00001071	1 / 1
P83916	Chromobox protein homolog 1	Unclassified protein	C00000677 C00001071 C00019064	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00000982 C00001071 C00019064	2 / 2
P04745	Alpha-amylase 1	Enzyme	C00000956 C00000982 C00001071	0 / 0
P15121	Aldose reductase	Enzyme	C00000982 C00001071 C00019064	0 / 0
P28907	ADP-ribosyl cyclase 1	Enzyme	C00000677 C00000956 C00001071	0 / 1
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00000677 C00000982 C00001071	2 / 0
O75496	Geminin	Unclassified protein	C00000677 C00000982 C00019064	0 / 0
P56817	Beta-secretase 1	A1A	C00000677 C00000956 C00008818	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00000677 C00000956 C00001071	0 / 0
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00000677 C00000982 C00001071	1 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00000956 C00001071 C00008818	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00000956 C00000982 C00019064	0 / 0
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00000677 C00000982 C00001071	1 / 1
Q01453	Peripheral myelin protein 22	Unclassified protein	C00000677 C00000956 C00001071	5 / 2
P11473	Vitamin D3 receptor	NR1I1	C00000956 C00001071 C00008818	2 / 3
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00000677 C00000956 C00001071	0 / 0
P11387	DNA topoisomerase 1	Isomerase	C00001071 C00040671 C00040672	0 / 0
P54132	Bloom syndrome protein	Enzyme	C00000677 C00000956 C00001071	1 / 2
P28482	Mitogen-activated protein kinase 1	Erk	C00000677 C00000956	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00000677 C00000956	0 / 0
Q05655	Protein kinase C delta type	Delta	C00000677 C00000956	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00000677 C00000956	0 / 0
P05129	Protein kinase C gamma type	Alpha	C00000677 C00000956	1 / 1
O94806	Serine/threonine-protein kinase D3	Pkd	C00000677 C00000956	0 / 0
P22303	Acetylcholinesterase	Hydrolase	C00000982 C00001071	1 / 0
P00374	Dihydrofolate reductase	Oxidoreductase	C00000956 C00008818	1 / 1
Q02156	Protein kinase C epsilon type	Eta	C00000677 C00000956	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00000677 C00001071	0 / 0
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00000982 C00001071	0 / 0
P05771	Protein kinase C beta type	Alpha	C00000677 C00000956	0 / 0
P24723	Protein kinase C eta type	Eta	C00000677 C00000956	1 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00000956 C00000982	5 / 1
Q16637	Survival motor neuron protein	Unclassified protein	C00000677 C00000956	4 / 1
Q9Y3R4	Sialidase-2	Enzyme	C00000956 C00001071	0 / 0
P02768	Serum albumin	Secreted protein	C00000956 C00008818	0 / 0
Q04759	Protein kinase C theta type	Delta	C00000677 C00000956	0 / 1
Q05513	Protein kinase C zeta type	Iota	C00000677 C00000956	0 / 0
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00000956 C00000982	3 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00000982 C00001071	0 / 0
Q04760	Lactoylglutathione lyase	Enzyme	C00000982 C00001071	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00000677 C00001071	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00001071 C00019064	0 / 0
P08254	Stromelysin-1	M10A	C00000677 C00000938	1 / 0
P10696	Alkaline phosphatase, placental-like	Enzyme	C00000956 C00001071	0 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00000677 C00001071	2 / 0
P08581	Hepatocyte growth factor receptor	TK tyrosine-protein kinase MET subfamily	C00000956 C00008818	2 / 3
P10415	Apoptosis regulator Bcl-2	Other cytosolic protein	C00000956 C00008818	0 / 7
P04062	Glucosylceramidase	Enzyme	C00000982 C00001071	6 / 4
P41743	Protein kinase C iota type	Iota	C00000677 C00000956	0 / 0
P45452	Collagenase 3	M10A	C00000677 C00000938	1 / 1
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00000677 C00000956	1 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00000677 C00001071	0 / 0
Q16678	Cytochrome P450 1B1	Cytochrome P450 1B1	C00000982 C00001071	4 / 4
P14780	Matrix metalloproteinase-9	M10A	C00000677 C00000938	2 / 2
Q15139	Serine/threonine-protein kinase D1	Pkd	C00000677 C00000956	0 / 0
P03956	Interstitial collagenase	M10A	C00000677 C00000938	0 / 1
P39900	Macrophage metalloelastase	M10A	C00000677 C00000938	0 / 0
P52209	6-phosphogluconate dehydrogenase, decarboxylating	Enzyme	C00000956 C00008818	0 / 0
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00000956 C00001071	0 / 0
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00000956 C00001071	3 / 1
P08253	72 kDa type IV collagenase	M10A	C00000677 C00000938	1 / 3
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00001071	0 / 0
Q9UM73	ALK tyrosine kinase receptor	TKL serine/threonine protein kinase STKR type 1 subfamily	C00008805	1 / 1
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00001071	0 / 0
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00000982	1 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00000677	0 / 0
P07711	Cathepsin L1	C1A	C00000956	0 / 0
P00734	Prothrombin	S1A	C00000956	4 / 2
P04150	Glucocorticoid receptor	NR3C1	C00000982	0 / 1
P06213	Insulin receptor	TK tyrosine-protein kinase INSR subfamily	C00001071	5 / 4
Q14790	Caspase-8	C14	C00001071	2 / 1
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00000982	5 / 3
P49841	Glycogen synthase kinase-3 beta	Gsk	C00019064	0 / 0
P06276	Cholinesterase	Hydrolase	C00001071	0 / 0
P00915	Carbonic anhydrase 1	Lyase	C00000956	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000982	0 / 1
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00000982	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00019064	0 / 0
P18433	Receptor-type tyrosine-protein phosphatase alpha	Receptor tyrosine-protein phosphatase	C00019064	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00000956	2 / 0
P35236	Tyrosine-protein phosphatase non-receptor type 7	Tyr	C00019064	0 / 0
P16152	Carbonyl reductase [NADPH] 1	Enzyme	C00000982	0 / 0
P07998	Ribonuclease pancreatic	Enzyme	C00000956	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00019064	0 / 0
P04278	Sex hormone-binding globulin	Secreted protein	C00000982	0 / 0
Q16790	Carbonic anhydrase 9	Lyase	C00000956	0 / 1
O43570	Carbonic anhydrase 12	Lyase	C00000956	1 / 2
Q9ULX7	Carbonic anhydrase 14	Lyase	C00000956	0 / 0
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00000982	2 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00001071	0 / 0
Q15746	Myosin light chain kinase, smooth muscle	Mlck	C00001071	1 / 1
P23280	Carbonic anhydrase 6	Lyase	C00000956	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00019064	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00000982	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00000982	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00001071	1 / 0
P03372	Estrogen receptor	NR3A1	C00000982	1 / 1
Q9HC97	G-protein coupled receptor 35	Kynurenic acid receptor	C00001071	0 / 0
O75828	Carbonyl reductase [NADPH] 3	Enzyme	C00000982	0 / 0
P24864	G1/S-specific cyclin-E1	Other cytosolic protein	C00000982	0 / 2
Q02880	DNA topoisomerase 2-beta	Isomerase	C00001071	0 / 0
P24941	Cyclin-dependent kinase 2	Cdc2	C00000982	0 / 0
P35228	Nitric oxide synthase, inducible	Enzyme	C00019064	1 / 1
P10586	Receptor-type tyrosine-protein phosphatase F	Receptor tyrosine-protein phosphatase	C00019064	0 / 0
P37059	Estradiol 17-beta-dehydrogenase 2	Enzyme	C00000982	0 / 0
P49327	Fatty acid synthase	Transferase	C00000956	0 / 0
P08183	Multidrug resistance protein 1	drug	C00000982	1 / 0
Q15046	Lysine--tRNA ligase	Enzyme	C00001071	2 / 1
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00000956	1 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00001071	0 / 0
P51452	Dual specificity protein phosphatase 3	Ser_Thr_Tyr	C00019064	0 / 0
P11309	Serine/threonine-protein kinase pim-1	Pim	C00001071	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00000956	1 / 2
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00001071	0 / 0
P10275	Androgen receptor	NR3C4	C00000982	3 / 4
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00000982	0 / 0
P07451	Carbonic anhydrase 3	Lyase	C00000956	0 / 0
P17706	Tyrosine-protein phosphatase non-receptor type 2	Tyr	C00019064	0 / 1
P16473	Thyrotropin receptor	Glycohormone receptor	C00000956	3 / 2
P62158	Calmodulin	Unclassified protein	C00000982	1 / 0
P29350	Tyrosine-protein phosphatase non-receptor type 6	Tyr	C00019064	0 / 0
P04054	Phospholipase A2	Enzyme	C00019064	0 / 0
P49888	Estrogen sulfotransferase	Enzyme	C00000982	0 / 0
P22748	Carbonic anhydrase 4	Lyase	C00000956	1 / 1
Q8TDU6	G-protein coupled bile acid receptor 1	Steroid-like ligand receptor	C00019064	0 / 0
P23469	Receptor-type tyrosine-protein phosphatase epsilon	Receptor tyrosine-protein phosphatase	C00019064	0 / 0
P24666	Low molecular weight phosphotyrosine protein phosphatase	Tyr	C00019064	0 / 0
P24298	Alanine aminotransferase 1	Enzyme	C00000677	0 / 0
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00000956	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00000982	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00001071	1 / 1
Q06124	Tyrosine-protein phosphatase non-receptor type 11	Tyr	C00019064	4 / 2
P42336	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Enzyme	C00001071	9 / 1
P43166	Carbonic anhydrase 7	Lyase	C00000956	0 / 0
P35218	Carbonic anhydrase 5A, mitochondrial	Lyase	C00000956	0 / 0
Q9Y2D0	Carbonic anhydrase 5B, mitochondrial	Lyase	C00000956	0 / 0
Q13093	Platelet-activating factor acetylhydrolase	Enzyme	C00000956	3 / 0
P33765	Adenosine receptor A3	Adenosine receptor	C00000677	0 / 0
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00000677	0 / 0
O60218	Aldo-keto reductase family 1 member B10	Enzyme	C00019064	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00001071	1 / 1
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00000982	0 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00000982	0 / 0
P31941	DNA dC->dU-editing enzyme APOBEC-3A	Enzyme	C00001071	0 / 0
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00000982	1 / 0
P14061	Estradiol 17-beta-dehydrogenase 1	Enzyme	C00000982	0 / 0
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00001071	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001071	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00000956	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00001071	2 / 1
Q9HCT0	Fibroblast growth factor 22	Unclassified protein	C00001071	0 / 0

105 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00000677 C00000982 C00001071
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000982 C00001071 C00019064
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000982 C00001071 C00019064
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00000677 C00001071 C00019064
847	CAT	catalase (EC:1.11.1.6)	C00001071 C00019064
6513	SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED	solute carrier family 2 (facilitated glucose transporter), member 1	C00000982 C00001071
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00000982 C00019064
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00000982 C00001071
4233	MET, AUTS9, HGFR, RCCP2, c-Met	met proto-oncogene (EC:2.7.10.1)	C00001071 C00019064
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000982 C00001071
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00000982 C00001071
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00001071 C00019064
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000982 C00001071
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00000677 C00001071
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00000677 C00019064
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00000982 C00019064
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00001071
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00000677
4547	MTTP, ABL, MTP	microsomal triglyceride transfer protein	C00000677
3458	IFNG, IFG, IFI	interferon, gamma	C00000677
1728	NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1	NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2)	C00000677
5155	PDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis	platelet-derived growth factor beta polypeptide	C00000677
5921	RASA1, CM-AVM, CMAVM, GAP, PKWS, RASA, RASGAP, p120GAP, p120RASGAP	RAS p21 protein activator (GTPase activating protein) 1	C00000677
6772	STAT1, CANDF7, ISGF-3, STAT91	signal transducer and activator of transcription 1, 91kDa	C00000677
7187	TRAF3, CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1	TNF receptor-associated factor 3	C00000677
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00000677
7498	XDH, XO, XOR	xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2)	C00000677
7507	XPA, XP1, XPAC	xeroderma pigmentosum, complementation group A	C00000677
7518	XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4	C00000677
10257	ABCC4, EST170205, MOAT-B, MOATB, MRP4	ATP-binding cassette, sub-family C (CFTR/MRP), member 4	C00000982
10057	ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	C00000982
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00000982
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00000982
8644	AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS	aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357)	C00000982
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00000982
249	ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP	alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1)	C00000982
405	ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2	aryl hydrocarbon receptor nuclear translocator	C00000982
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00000677
9518	GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB	growth differentiation factor 15	C00000677
2621	GAS6, AXLLG, AXSF	growth arrest-specific 6	C00000677
1588	CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM	cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000982
2248	FGF3, HBGF-3, INT2	fibroblast growth factor 3	C00000677
8817	FGF18, FGF-18, ZFGF5	fibroblast growth factor 18	C00000677
1950	EGF, HOMG4, URG	epidermal growth factor	C00000677
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00000982
1630	DCC, CRC18, CRCR1, IGDCC1, MRMV1	deleted in colorectal carcinoma	C00000677
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00000982
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00000982
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00000982
3757	KCNH2, ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1	potassium voltage-gated channel, subfamily H (eag-related), member 2	C00000982
5444	PON1, ESA, MVCD5, PON	paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81)	C00000982
6566	SLC16A1, HHF7, MCT, MCT1	solute carrier family 16 (monocarboxylate transporter), member 1	C00000982
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00000677
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00000982
6818	SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1)	C00000982
993	CDC25A, CDC25A2	cell division cycle 25A (EC:3.1.3.48)	C00000677
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000982
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00000982
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00000982
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00000982
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00000982
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00000982
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00000982
1244	ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	C00001071
397	ARHGDIB, D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2	Rho GDP dissociation inhibitor (GDI) beta	C00001071
581	BAX, BCL2L4	BCL2-associated X protein	C00001071
8900	CCNA1	cyclin A1	C00000677
891	CCNB1, CCNB	cyclin B1	C00001071
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00001071
1031	CDKN2C, INK4C, p18, p18-INK4C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	C00001071
1312	COMT	catechol-O-methyltransferase (EC:2.1.1.6)	C00001071
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00001071
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00001071
1786	DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT	DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37)	C00001071
54583	EGLN1, C1orf12, ECYT3, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6	egl-9 family hypoxia-inducible factor 1 (EC:1.14.11.29)	C00001071
2203	FBP1, FBP	fructose-1,6-bisphosphatase 1 (EC:3.1.3.11)	C00001071
3082	HGF, DFNB39, F-TCF, HGFB, HPTA, SF	hepatocyte growth factor (hepapoietin A; scatter factor)	C00001071
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00001071
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00000677
338	APOB, FLDB, LDLCQ4	apolipoprotein B	C00000677
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00001071
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00001071
8505	PARG, PARG99	poly (ADP-ribose) glycohydrolase (EC:3.2.1.143)	C00001071
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00001071
8000	PSCA, PRO232	prostate stem cell antigen	C00001071
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00001071
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00001071
23411	SIRT1, SIR2L1	sirtuin 1	C00001071
335	APOA1	apolipoprotein A-I	C00000677
9540	TP53I3, PIG3	tumor protein p53 inducible protein 3	C00001071
8626	TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L	tumor protein p63	C00001071
7161	TP73, P73	tumor protein p73	C00001071
8877	SPHK1, SPHK	sphingosine kinase 1 (EC:2.7.1.91)	C00000938
177	AGER, RAGE	advanced glycosylation end product-specific receptor	C00019064
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00019064
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00019064
3065	HDAC1, GON-10, HD1, RPD3, RPD3L1	histone deacetylase 1 (EC:3.5.1.98)	C00019064
3146	HMGB1, HMG1, HMG3, SBP-1	high mobility group box 1	C00019064
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00019064
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00019064
5052	PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2	peroxiredoxin 1 (EC:1.11.1.15)	C00019064
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00019064
6401	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2	selectin E	C00019064
7150	TOP1, TOPI	topoisomerase (DNA) I (EC:5.99.1.2)	C00019064
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00019064

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