class name | count |
---|---|
rosids | 5 |
eudicotyledons | 1 |
class name | count |
---|---|
Enterobacteriaceae | 5 |
Brassicaceae | 5 |
Amaranthaceae | 1 |
br08003 Category | # of metabolite |
---|
br08003 Category | KEGG ID | KNApSAcK ID |
---|
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
---|---|---|---|---|---|---|
C00001539
![]() |
Folic acid
|
CHEMBL277040
CHEMBL1622 |
D005492
|
34 / 32 / 27 | 178 / 101 |
![]() |
C00007248
![]() |
7,8-Dihydrofolate
/ 7,8-Dihydrofolic acid |
CHEMBL46294
CHEMBL1371525 |
C010920
|
10 / 10 / 14 | 3 / 0 |
![]() |
C00007249
![]() |
THF
/ THFA / Tetrahydrofolate / Tetrahydrofolic acid |
CHEMBL2021342
CHEMBL2074655 |
1 / 0 / 0 |
![]() |
||
C00007250
![]() |
5,10-Methylenetetrahydrofolic acid
|
CHEMBL117348
|
![]() |
|||
C00007251
![]() |
10-Formyl-THF
|
![]() |
||||
C00007252
![]() |
5-Methyl-tetrahydrofolate
/ 5-Methyltetrahydrofolic acid |
CHEMBL1221561
CHEMBL1231574 CHEMBL2358502 |
C005984
|
7 / 3 |
![]() |
|
C00019687
![]() |
Anhydroleucovorin
/ 5,10-Methenyltetrahydrofolate |
CHEMBL46521
|
C018092
|
2 / 2 / 1 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P00352 | Retinal dehydrogenase 1 | Enzyme | C00001539 C00007248 | 0 / 0 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001539 C00007248 | 1 / 2 |
O00255 | Menin | Unclassified protein | C00001539 C00007248 | 2 / 5 |
Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001539 C00007248 | 1 / 1 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001539 C00007248 | 0 / 0 |
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001539 C00007248 | 0 / 0 |
P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00001539 C00007248 | 2 / 2 |
Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001539 C00007248 | 3 / 3 |
P06280 | Alpha-galactosidase A | Enzyme | C00001539 C00007248 | 1 / 1 |
P04818 | Thymidylate synthase | Transferase | C00001539 C00019687 | 0 / 0 |
Q05932 | Folylpolyglutamate synthase, mitochondrial | Enzyme | C00001539 C00007249 | 0 / 0 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001539 | 0 / 0 |
O15439 | Multidrug resistance-associated protein 4 | Unclassified protein | C00001539 | 0 / 0 |
P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00001539 | 2 / 0 |
P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00001539 | 0 / 0 |
O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00001539 | 0 / 0 |
P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00001539 | 2 / 2 |
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001539 | 1 / 0 |
O75496 | Geminin | Unclassified protein | C00001539 | 0 / 0 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001539 | 0 / 1 |
Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00001539 | 2 / 0 |
P16473 | Thyrotropin receptor | Glycohormone receptor | C00001539 | 3 / 2 |
P11586 | C-1-tetrahydrofolate synthase, cytoplasmic | Enzyme | C00019687 | 2 / 1 |
P55210 | Caspase-7 | C14 | C00007248 | 0 / 0 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001539 | 1 / 1 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001539 | 0 / 1 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00001539 | 0 / 0 |
P37840 | Alpha-synuclein | Unclassified protein | C00001539 | 4 / 2 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001539 | 0 / 0 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00001539 | 0 / 0 |
O15245 | Solute carrier family 22 member 1 | Drug uniporter | C00001539 | 0 / 0 |
P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00001539 | 1 / 1 |
P04062 | Glucosylceramidase | Enzyme | C00001539 | 6 / 4 |
P06746 | DNA polymerase beta | Enzyme | C00001539 | 0 / 0 |
Q96QA9 | Multidrug resistance associated protein | Unclassified protein | C00001539 | 0 / 0 |
Q96J66 | ATP-binding cassette sub-family C member 11 | Unclassified protein | C00001539 | 1 / 0 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
10840 | ALDH1L1, 10-FTHFDH, 10-fTHF, FDH, FTHFD | aldehyde dehydrogenase 1 family, member L1 (EC:1.5.1.6) |
C00001539
C00007252
|
2348 | FOLR1, FBP, FOLR | folate receptor 1 (adult) |
C00001539
C00007252
|
4524 | MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) (EC:1.5.1.20) |
C00001539
C00007252
|
4548 | MTR, HMAG, MS, cblG | 5-methyltetrahydrofolate-homocysteine methyltransferase (EC:2.1.1.13) |
C00001539
C00007252
|
9 | NAT1, AAC1, MNAT, NAT-1, NATI | N-acetyltransferase 1 (arylamine N-acetyltransferase) (EC:2.3.1.5) |
C00001539
C00007248
|
6573 | SLC19A1, CHMD, FOLT, IFC1, REFC, RFC1 | solute carrier family 19 (folate transporter), member 1 |
C00001539
C00007252
|
113235 | SLC46A1, G21, HCP1, PCFT | solute carrier family 46 (folate transporter), member 1 |
C00001539
C00007252
|
3480 | IGF1R, CD221, IGFIR, IGFR, JTK13 | insulin-like growth factor 1 receptor (EC:2.7.10.1) |
C00001539
C00007248
|
5328 | PLAU, ATF, BDPLT5, QPD, UPA, URK, u-PA | plasminogen activator, urokinase (EC:3.4.21.73) |
C00001539
|
10891 | PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
C00007248
|
4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00001539
|
9429 | ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1 | ATP-binding cassette, sub-family G (WHITE), member 2 |
C00001539
|
43 | ACHE, ACEE, ARACHE, N-ACHE, YT | acetylcholinesterase (EC:3.1.1.7) |
C00001539
|
57007 | ACKR3, CMKOR1, CXC-R7, CXCR-7, CXCR7, GPR159, RDC-1, RDC1 | atypical chemokine receptor 3 |
C00001539
|
51554 | ACKR4, CC-CKR-11, CCBP2, CCR-11, CCR10, CCR11, CCRL1, CCX_CKR, CCX-CKR, CKR-11, PPR1, VSHK1 | atypical chemokine receptor 4 |
C00001539
|
59 | ACTA2, AAT6, ACTSA, MYMY5 | actin, alpha 2, smooth muscle, aorta |
C00001539
|
70 | ACTC1, ACTC, ASD5, CMD1R, CMH11, LVNC4 | actin, alpha, cardiac muscle 1 |
C00001539
|
60312 | AFAP1, AFAP, AFAP-110, AFAP110 | actin filament associated protein 1 |
C00001539
|
10551 | AGR2, AG2, GOB-4, HAG-2, PDIA17, XAG-2 | anterior gradient 2 |
C00001539
|
205 | AK4, AK_4, AK3, AK3L1, AK3L2 | adenylate kinase 4 (EC:2.7.4.10 2.7.4.6) |
C00001539
|
9590 | AKAP12, AKAP250, SSeCKS | A kinase (PRKA) anchor protein 12 |
C00001539
|
213 | ALB, PRO0883, PRO0903, PRO1341 | albumin |
C00001539
|
216 | ALDH1A1, ALDC, ALDH-E1, ALDH1, ALDH11, PUMB1, RALDH1 | aldehyde dehydrogenase 1 family, member A1 (EC:1.2.1.36) |
C00001539
|
27063 | ANKRD1, ALRP, C-193, CARP, CVARP, MCARP, bA320F15.2 | ankyrin repeat domain 1 (cardiac muscle) |
C00001539
|
312 | ANXA13, ANX13, ISA | annexin A13 |
C00001539
|
338 | APOB, FLDB, LDLCQ4 | apolipoprotein B |
C00001539
|
9411 | ARHGAP29, PARG1, RP11-255E17.1 | Rho GTPase activating protein 29 |
C00001539
|
10123 | ARL4C, ARL7, LAK | ADP-ribosylation factor-like 4C |
C00001539
|
57412 | AS3MT, CYT19 | arsenic (+3 oxidation state) methyltransferase (EC:2.1.1.137) |
C00001539
|
1388 | ATF6B, CREB-RP, CREBL1, G13 | activating transcription factor 6 beta |
C00001539
|
472 | ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1 | ataxia telangiectasia mutated (EC:2.7.11.1) |
C00001539
|
567 | B2M | beta-2-microglobulin |
C00001539
|
581 | BAX, BCL2L4 | BCL2-associated X protein |
C00001539
|
596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00001539
|
10018 | BCL2L11, BAM, BIM, BOD | BCL2-like 11 (apoptosis facilitator) |
C00001539
|
51283 | BFAR, BAR, RNF47 | bifunctional apoptosis regulator |
C00001539
|
329 | BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 | baculoviral IAP repeat containing 2 |
C00001539
|
330 | BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 | baculoviral IAP repeat containing 3 |
C00001539
|
664 | BNIP3, NIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
C00001539
|
665 | BNIP3L, BNIP3a, NIX | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
C00001539
|
837 | CASP4, ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX | caspase 4, apoptosis-related cysteine peptidase (EC:3.4.22.57) |
C00001539
|
839 | CASP6, MCH2 | caspase 6, apoptosis-related cysteine peptidase (EC:3.4.22.59) |
C00001539
|
841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00001539
|
6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00001539
|
595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00001539
|
896 | CCND3 | cyclin D3 |
C00001539
|
898 | CCNE1, CCNE | cyclin E1 |
C00001539
|
999 | CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO | cadherin 1, type 1, E-cadherin (epithelial) |
C00001539
|
1012 | CDH13, CDHH, P105 | cadherin 13 (EC:3.6.1.3) |
C00001539
|
1001 | CDH3, CDHP, HJMD, PCAD | cadherin 3, type 1, P-cadherin (placental) |
C00001539
|
1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00001539
|
1027 | CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
C00001539
|
1029 | CDKN2A, ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16 | cyclin-dependent kinase inhibitor 2A |
C00001539
|
1111 | CHEK1, CHK1 | checkpoint kinase 1 (EC:2.7.11.1) |
C00001539
|
27141 | CIDEB | cell death-inducing DFFA-like effector b |
C00001539
|
1047 | CLGN | calmegin |
C00001539
|
1270 | CNTF, HCNTF | ciliary neurotrophic factor |
C00001539
|
1401 | CRP, PTX1 | C-reactive protein, pentraxin-related |
C00001539
|
1499 | CTNNB1, CTNNB, MRD19, armadillo | catenin (cadherin-associated protein), beta 1, 88kDa |
C00001539
|
1075 | CTSC, CPPI, DPP-I, DPP1, DPPI, HMS, JP, JPD, PALS, PDON1, PLS | cathepsin C (EC:3.4.14.1) |
C00001539
|
7913 | DEK, D6S231E | DEK oncogene |
C00001539
|
1719 | DHFR, DHFRP1, DYR | dihydrofolate reductase (EC:1.5.1.3) |
C00001539
|
22943 | DKK1, DKK-1, SK | dickkopf WNT signaling pathway inhibitor 1 |
C00001539
|
1786 | DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT | DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) |
C00001539
|
1788 | DNMT3A, DNMT3A2, M.HsaIIIA | DNA (cytosine-5-)-methyltransferase 3 alpha (EC:2.1.1.37) |
C00001539
|
1789 | DNMT3B, ICF, ICF1, M.HsaIIIB | DNA (cytosine-5-)-methyltransferase 3 beta (EC:2.1.1.37) |
C00001539
|
1805 | DPT, TRAMP | dermatopontin |
C00001539
|
1907 | EDN2, ET2, PPET2 | endothelin 2 |
C00001539
|
2051 | EPHB6, HEP | EPH receptor B6 (EC:2.7.10.1) |
C00001539
|
2114 | ETS2, ETS2IT1 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
C00001539
|
84668 | FAM126A, DRCTNNB1A, HCC, HLD5, HYCC1 | family with sequence similarity 126, member A |
C00001539
|
355 | FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 | Fas cell surface death receptor |
C00001539
|
2243 | FGA, Fib2 | fibrinogen alpha chain |
C00001539
|
2273 | FHL1, FHL-1, FHL1A, FHL1B, FLH1A, KYOT, SLIM, SLIM-1, SLIM1, SLIMMER, XMPMA | four and a half LIM domains 1 |
C00001539
|
2350 | FOLR2, BETA-HFR, FBP, FBP/PL-1, FR-BETA, FR-P3 | folate receptor 2 (fetal) |
C00001539
|
2356 | FPGS | folylpolyglutamate synthase (EC:6.3.2.17) |
C00001539
|
2512 | FTL, NBIA3 | ferritin, light polypeptide |
C00001539
|
2621 | GAS6, AXLLG, AXSF | growth arrest-specific 6 |
C00001539
|
9518 | GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB | growth differentiation factor 15 |
C00001539
|
79153 | GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
C00001539
|
8836 | GGH, GH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) (EC:3.4.19.9) |
C00001539
|
2697 | GJA1, AVSD3, CMDR, CX43, DFNB38, GJAL, HLHS1, HSS, ODDD | gap junction protein, alpha 1, 43kDa |
C00001539
|
2875 | GPT, AAT1, ALT1, GPT1 | glutamic-pyruvate transaminase (alanine aminotransferase) (EC:2.6.1.2) |
C00001539
|
2987 | GUK1, GMK | guanylate kinase 1 (EC:2.7.4.8) |
C00001539
|
8739 | HRK, DP5, HARAKIRI | harakiri, BCL2 interacting protein (contains only BH3 domain) |
C00001539
|
27129 | HSPB7, cvHSP | heat shock 27kDa protein family, member 7 (cardiovascular) |
C00001539
|
3397 | ID1, ID, bHLHb24 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
C00001539
|
8519 | IFITM1, 9-27, CD225, DSPA2a, IFI17, LEU13 | interferon induced transmembrane protein 1 |
C00001539
|
10410 | IFITM3, 1-8U, DSPA2b, IP15 | interferon induced transmembrane protein 3 |
C00001539
|
3488 | IGFBP5, IBP5 | insulin-like growth factor binding protein 5 |
C00001539
|
3558 | IL2, IL-2, TCGF, lymphokine | interleukin 2 |
C00001539
|
3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00001539
|
3638 | INSIG1, CL-6, CL6 | insulin induced gene 1 |
C00001539
|
3675 | ITGA3, CD49C, GAP-B3, GAPB3, ILNEB, MSK18, VCA-2, VL3A, VLA3a | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
C00001539
|
3676 | ITGA4, CD49D, IA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) |
C00001539
|
3678 | ITGA5, CD49e, FNRA, VLA5A | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
C00001539
|
3655 | ITGA6, CD49f, ITGA6B, VLA-6 | integrin, alpha 6 |
C00001539
|
3688 | ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
C00001539
|
3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00001539
|
9735 | KNTC1, ROD | kinetochore associated 1 |
C00001539
|
3861 | KRT14, CK14, EBS3, EBS4, K14, NFJ | keratin 14 |
C00001539
|
7851 | MALL, BENE | mal, T-cell differentiation protein-like |
C00001539
|
4131 | MAP1B, FUTSCH, MAP5 | microtubule-associated protein 1B |
C00001539
|
5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00001539
|
5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00001539
|
8932 | MBD2, DMTase, NY-CO-41 | methyl-CpG binding domain protein 2 |
C00001539
|
4170 | MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT | myeloid cell leukemia sequence 1 (BCL2-related) |
C00001539
|
4193 | MDM2, ACTFS, HDMX, hdm2 | MDM2 oncogene, E3 ubiquitin protein ligase |
C00001539
|
11343 | MGLL, HU-K5, HUK5, MAGL, MGL | monoglyceride lipase (EC:3.1.1.23) |
C00001539
|
4255 | MGMT | O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63) |
C00001539
|
100507436 | MICA, MIC-A, PERB11.1 | MHC class I polypeptide-related sequence A |
C00001539
|
4282 | MIF, GIF, GLIF, MMIF | macrophage migration inhibitory factor (glycosylation-inhibiting factor) (EC:5.3.3.12 5.3.2.1) |
C00001539
|
4311 | MME, CALLA, CD10, NEP, SFE | membrane metallo-endopeptidase (EC:3.4.24.11) |
C00001539
|
4314 | MMP3, CHDS6, MMP-3, SL-1, STMY, STMY1, STR1 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) (EC:3.4.24.17) |
C00001539
|
4504 | MT3, GIF, GIFB, GRIF, ZnMT3 | metallothionein 3 |
C00001539
|
4552 | MTRR, MSR, cblE | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (EC:1.16.1.8) |
C00001539
|
4582 | MUC1, CA_15-3, CD227, EMA, H23AG, KL-6, MAM6, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM | mucin 1, cell surface associated |
C00001539
|
4651 | MYO10 | myosin X |
C00001539
|
4684 | NCAM1, CD56, MSK39, NCAM | neural cell adhesion molecule 1 (EC:2.7.11.1) |
C00001539
|
653361 | NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox | neutrophil cytosolic factor 1 |
C00001539
|
3340 | NDST1, HSST, NST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 (EC:2.8.2.8) |
C00001539
|
4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00001539
|
4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00001539
|
4833 | NME4, NDPK-D, NM23H4, nm23-H4 | NME/NM23 nucleoside diphosphate kinase 4 (EC:2.7.4.6) |
C00001539
|
4855 | NOTCH4, INT3, NOTCH3 | notch 4 |
C00001539
|
9315 | NREP, C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17 | neuronal regeneration related protein |
C00001539
|
4913 | NTHL1, NTH1, OCTS3 | nth endonuclease III-like 1 (E. coli) (EC:4.2.99.18) |
C00001539
|
59277 | NTN4, PRO3091 | netrin 4 |
C00001539
|
142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00001539
|
26577 | PCOLCE2, PCPE2 | procollagen C-endopeptidase enhancer 2 |
C00001539
|
5154 | PDGFA, PDGF-A, PDGF1 | platelet-derived growth factor alpha polypeptide |
C00001539
|
5204 | PFDN5, MM-1, MM1, PFD5 | prefoldin subunit 5 |
C00001539
|
5230 | PGK1, MIG10, PGKA | phosphoglycerate kinase 1 (EC:2.7.2.3) |
C00001539
|
10424 | PGRMC2, DG6, PMBP | progesterone receptor membrane component 2 |
C00001539
|
5295 | PIK3R1, AGM7, GRB1, p85, p85-ALPHA | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
C00001539
|
5111 | PCNA | proliferating cell nuclear antigen |
C00007252
|
5329 | PLAUR, CD87, U-PAR, UPAR, URKR | plasminogen activator, urokinase receptor |
C00001539
|
5420 | PODXL, Gp200, PC, PCLP, PCLP-1 | podocalyxin-like |
C00001539
|
5591 | PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 | protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1) |
C00001539
|
51334 | PRR16, DSC54 | proline rich 16 |
C00001539
|
5753 | PTK6, BRK | protein tyrosine kinase 6 (EC:2.7.10.2) |
C00001539
|
83956 | RACGAP1P, FKSG42 | Rac GTPase activating protein 1 pseudogene |
C00001539
|
5894 | RAF1, CRAF, NS5, Raf-1, c-Raf | v-raf-1 murine leukemia viral oncogene homolog 1 (EC:2.7.11.1) |
C00001539
|
5921 | RASA1, CM-AVM, CMAVM, GAP, PKWS, RASA, RASGAP, p120GAP, p120RASGAP | RAS p21 protein activator (GTPase activating protein) 1 |
C00001539
|
8434 | RECK, ST15 | reversion-inducing-cysteine-rich protein with kazal motifs |
C00001539
|
389 | RHOC, ARH9, ARHC, H9, RHOH9 | ras homolog family member C |
C00001539
|
6119 | RPA3, REPA3 | replication protein A3, 14kDa |
C00001539
|
6193 | RPS5, S5 | ribosomal protein S5 |
C00001539
|
6281 | S100A10, 42C, ANX2L, ANX2LG, CAL1L, CLP11, Ca[1], GP11, P11, p10 | S100 calcium binding protein A10 |
C00001539
|
6275 | S100A4, 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98 | S100 calcium binding protein A4 |
C00001539
|
6303 | SAT1, DC21, KFSD, KFSDX, SAT, SSAT, SSAT-1 | spermidine/spermine N1-acetyltransferase 1 (EC:2.3.1.57) |
C00001539
|
5055 | SERPINB2, HsT1201, PAI, PAI-2, PAI2, PLANH2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
C00001539
|
6470 | SHMT1, CSHMT, SHMT | serine hydroxymethyltransferase 1 (soluble) (EC:2.1.2.1) |
C00001539
|
6566 | SLC16A1, HHF7, MCT, MCT1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
C00001539
|
6580 | SLC22A1, HOCT1, OCT1, oct1_cds | solute carrier family 22 (organic cation transporter), member 1 |
C00001539
|
6514 | SLC2A2, GLUT2 | solute carrier family 2 (facilitated glucose transporter), member 2 |
C00001539
|
30061 | SLC40A1, FPN1, HFE4, IREG1, MST079, MTP1, SLC11A3 | solute carrier family 40 (iron-regulated transporter), member 1 |
C00001539
|
9056 | SLC7A7, LAT3, LPI, MOP-2, Y+LAT1, y+LAT-1 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
C00001539
|
6659 | SOX4, EVI16 | SRY (sex determining region Y)-box 4 |
C00001539
|
6667 | SP1 | Sp1 transcription factor |
C00001539
|
6690 | SPINK1, PCTT, PSTI, Spink3, TATI, TCP | serine peptidase inhibitor, Kazal type 1 |
C00001539
|
6876 | TAGLN, SM22, SMCC, TAGLN1, WS3-10 | transgelin |
C00001539
|
4071 | TM4SF1, H-L6, L6, M3S1, TAAL6 | transmembrane 4 L six family member 1 |
C00001539
|
8795 | TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 | tumor necrosis factor receptor superfamily, member 10b |
C00001539
|
8764 | TNFRSF14, ATAR, CD270, HVEA, HVEM, LIGHTR, TR2 | tumor necrosis factor receptor superfamily, member 14 |
C00001539
|
7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00001539
|
7185 | TRAF1, EBI6, MGC:10353 | TNF receptor-associated factor 1 |
C00001539
|
9618 | TRAF4, CART1, MLN62, RNF83 | TNF receptor-associated factor 4 |
C00001539
|
7189 | TRAF6, MGC:3310, RNF85 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
C00001539
|
10293 | TRAIP, RNF206, TRIP | TRAF interacting protein |
C00001539
|
7846 | TUBA1A, B-ALPHA-1, LIS3, TUBA3 | tubulin, alpha 1a |
C00001539
|
55000 | TUG1, LINC00080, NCRNA00080, TI-227H | taurine up-regulated 1 (non-protein coding) |
C00001539
|
10628 | TXNIP, EST01027, HHCPA78, THIF, VDUP1 | thioredoxin interacting protein |
C00001539
|
7298 | TYMS, HST422, TMS, TS | thymidylate synthetase (EC:2.1.1.45) |
C00001539
|
54532 | USP53 | ubiquitin specific peptidase 53 |
C00001539
|
7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00001539
|
389136 | VGLL3, VGL-3, VGL3 | vestigial like 3 (Drosophila) |
C00001539
|
8840 | WISP1, CCN4, WISP1c, WISP1i, WISP1tc | WNT1 inducible signaling pathway protein 1 |
C00001539
|
7474 | WNT5A, hWNT5A | wingless-type MMTV integration site family, member 5A |
C00001539
|
51222 | ZNF219, ZFP219 | zinc finger protein 219 |
C00001539
|
OMIM | preferred title | UniProt |
---|---|---|
#300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
#117800 | Apocrine gland secretion, variation in |
Q96J66
|
#614490 | Blood group, junior system; jr |
Q9UNQ0
|
#114500 | Colorectal cancer; crc |
P11586
P84022 |
#127750 | Dementia, lewy body; dlb |
P37840
|
#119900 | Digital clubbing, isolated congenital |
P15428
|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#301500 | Fabry disease |
P06280
|
#608013 | Gaucher disease, perinatal lethal |
P04062
|
#230800 | Gaucher disease, type i |
P04062
|
#230900 | Gaucher disease, type ii |
P04062
|
#231000 | Gaucher disease, type iii |
P04062
|
#231005 | Gaucher disease, type iiic |
P04062
|
#232300 | Glycogen storage disease ii |
P10253
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#603373 | Hyperthyroidism, familial gestational |
P16473
|
#609152 | Hyperthyroidism, nonautoimmune |
P16473
|
#259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
#275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
#613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
#300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
#300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#601634 | Neural tube defects, folate-sensitive |
P11586
|
#257200 | Niemann-pick disease, type a |
P17405
|
#607616 | Niemann-pick disease, type b |
P17405
|
#168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
#605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
#168600 | Parkinson disease, late-onset; pd |
P04062
P37840 |
#607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
#138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
|
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00066 | Lewy body dementia (LBD) |
P04062
(related)
P37840 (related) |
H00126 | Gaucher disease |
P04062
(related)
|
H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
H00125 | Fabry disease |
P06280
(related)
|
H00036 | Osteosarcoma |
P08684
(marker)
|
H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
H00262 | Spina bifida |
P11586
(related)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
H01269 | Congenital hyperthyroidism |
P16473
(related)
|
H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00057 | Parkinson's disease (PD) |
P37840
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
MESH or OMIM | name |
KNApSAcK
metabolite |
---|---|---|
D001321 | Autistic Disorder |
C00007252
C00001539 |
D009436 | Neural Tube Defects |
C00007252
C00001539 |
D009374 | Neoplasms, Experimental |
C00001539
|
D000014 | Abnormalities, Drug-Induced |
C00001539
|
D058186 | Acute Kidney Injury |
C00001539
|
D000236 | Adenoma |
C00001539
|
D000370 | Ageusia |
C00001539
|
D000430 | Alcohol Withdrawal Delirium |
C00001539
|
D000544 | Alzheimer Disease |
C00001539
|
D000740 | Anemia |
C00001539
|
D000741 | Anemia, Aplastic |
C00001539
|
D000743 | Anemia, Hemolytic |
C00001539
|
D000744 | Anemia, Hemolytic, Autoimmune |
C00001539
|
D000748 | Anemia, Macrocytic |
C00001539
|
D000749 | Anemia, Megaloblastic |
C00001539
|
D000755 | Anemia, Sickle Cell |
C00001539
|
D000756 | Anemia, Sideroblastic |
C00001539
|
D000757 | Anencephaly |
C00001539
|
D001002 | Anuria |
C00001539
|
D001161 | Arteriosclerosis |
C00001539
|
D015535 | Arthritis, Psoriatic |
C00001539
|
D001259 | Ataxia |
C00001539
|
D001284 | Atrophy |
C00001539
|
D001714 | Bipolar Disorder |
C00001539
|
D001925 | Brain Damage, Chronic |
C00001539
|
D001927 | Brain Diseases |
C00001539
|
D001943 | Breast Neoplasms |
C00001539
|
D002292 | Carcinoma, Renal Cell |
C00001539
|
D018376 | Cardiovascular Abnormalities |
C00001539
|
D002318 | Cardiovascular Diseases |
C00001539
|
D002386 | Cataract |
C00001539
|
D002524 | Cerebellar Ataxia |
C00001539
|
D002971 | Cleft Lip |
C00001539
|
D002972 | Cleft Palate |
C00001539
|
D003072 | Cognition Disorders |
C00001539
|
D015179 | Colorectal Neoplasms |
C00001539
|
D003117 | Color Vision Defects |
C00001539
|
D000013 | Congenital Abnormalities |
C00001539
|
D023903 | Coronary Restenosis |
C00001539
|
D003704 | Dementia |
C00001539
|
D003866 | Depressive Disorder |
C00001539
|
D003924 | Diabetes Mellitus, Type 2 |
C00001539
|
D004195 | Disease Models, Animal |
C00001539
|
D004244 | Dizziness |
C00001539
|
D056486 | Drug-Induced Liver Injury |
C00001539
|
D064420 | Drug-Related Side Effects and Adverse Reactions |
C00001539
|
D016889 | Endometrial Neoplasms |
C00001539
|
D004827 | Epilepsy |
C00001539
|
D017889 | Exfoliation Syndrome |
C00001539
|
D005235 | Fatty Liver, Alcoholic |
C00001539
|
D063647 | Fetal Alcohol Spectrum Disorders |
C00001539
|
D005494 | Folic Acid Deficiency |
C00001539
|
D005756 | Gastritis |
C00001539
|
D005832 | Genital Diseases, Male |
C00001539
|
D005901 | Glaucoma |
C00001539
|
D006261 | Headache |
C00001539
|
D006330 | Heart Defects, Congenital |
C00001539
|
D006402 | Hematologic Diseases |
C00001539
|
D006679 | HIV Seropositivity |
C00001539
|
D006849 | Hydrocephalus |
C00001539
|
D020138 | HYPERHOMOCYSTEINEMIA |
C00001539
|
D006948 | Hyperkinesis |
C00001539
|
D006973 | Hypertension |
C00001539
|
D007021 | Hypospadias |
C00001539
|
D007674 | Kidney Diseases |
C00001539
|
D007676 | Kidney Failure, Chronic |
C00001539
|
D007683 | Kidney Tubular Necrosis, Acute |
C00001539
|
D008107 | Liver Diseases |
C00001539
|
D008180 | Lupus Erythematosus, Systemic |
C00001539
|
D016778 | Malaria, Falciparum |
C00001539
|
D019767 | Maxillofacial Abnormalities |
C00001539
|
D008545 | Melanoma |
C00001539
|
D052016 | Mucositis |
C00001539
|
D009135 | Muscular Diseases |
C00001539
|
D009303 | Nasopharyngeal Neoplasms |
C00001539
|
D009369 | Neoplasms |
C00001539
|
D006712 | Homocystinuria |
C00007252
|
D009395 | Nephritis, Interstitial |
C00001539
|
D009422 | Nervous System Diseases |
C00001539
|
D009503 | Neutropenia |
C00001539
|
C541083 | Non-alcoholic Fatty Liver Disease |
C00001539
|
D009901 | Optic Nerve Diseases |
C00001539
|
D010018 | Osteomalacia |
C00001539
|
D010523 | Peripheral Nervous System Diseases |
C00001539
|
D049188 | Prenatal Injuries |
C00001539
|
D011507 | Proteinuria |
C00001539
|
D011565 | Psoriasis |
C00001539
|
D011602 | Psychophysiologic Disorders |
C00001539
|
D051437 | Renal Insufficiency |
C00001539
|
D012559 | Schizophrenia |
C00001539
|
D012607 | Scotoma |
C00001539
|
D012640 | Seizures |
C00001539
|
D012851 | Sinus Thrombosis, Intracranial |
C00001539
|
D012871 | Skin Diseases |
C00001539
|
D013118 | Spinal Cord Diseases |
C00001539
|
D016135 | Spinal Dysraphism |
C00001539
|
D013182 | Sprue, Tropical |
C00001539
|
D013274 | Stomach Neoplasms |
C00001539
|
D020521 | Stroke |
C00001539
|
D013921 | Thrombocytopenia |
C00001539
|
D014123 | Toxoplasmosis |
C00001539
|
D014511 | Uremia |
C00001539
|