Species

KNApSAcK Entry

Organism name Chamaecrista mimosoides
Genus Chamaecrista
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Chamaecrista mimosoides
Linked NCBI taxonomy ID 948715
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000555 External link 512 Emodin
CHEMBL289277
D004642
109 / 88 / 91 68 / 9 No. 41 No. 62
C00000568 External link 512 Chrysophanol
CHEMBL41092
C027113
20 / 17 / 20 1 / 0 No. 41 No. 62
C00000674 External link 512 Luteolin
CHEMBL151
D047311
99 / 91 / 95 76 / 6 No. 71 No. 15

Human Protein / Gene in interactions

170 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00000555 C00000568 C00000674 1 / 2
P00352 Retinal dehydrogenase 1 Enzyme C00000555 C00000568 C00000674 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00000555 C00000568 C00000674 3 / 2
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00000555 C00000568 C00000674 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00000555 C00000568 C00000674 0 / 1
O00255 Menin Unclassified protein C00000555 C00000568 C00000674 2 / 5
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00000555 C00000568 C00000674 1 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00000555 C00000568 C00000674 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000555 C00000568 C00000674 0 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00000555 C00000568 C00000674 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00000555 C00000568 C00000674 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00000555 C00000568 C00000674 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00000555 C00000568 C00000674 0 / 0
P03372 Estrogen receptor NR3A1 C00000555 C00000674 1 / 1
P06239 Tyrosine-protein kinase Lck Src C00000555 C00000674 0 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00000568 C00000674 0 / 0
P06746 DNA polymerase beta Enzyme C00000555 C00000674 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00000555 C00000674 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00000555 C00000674 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00000568 C00000674 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000555 C00000674 1 / 1
P16050 Arachidonate 15-lipoxygenase Enzyme C00000555 C00000674 0 / 0
P10275 Androgen receptor NR3C4 C00000555 C00000674 3 / 4
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00000555 C00000568 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00000555 C00000674 3 / 3
P28482 Mitogen-activated protein kinase 1 Erk C00000555 C00000568 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00000555 C00000674 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000555 C00000674 1 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00000555 C00000674 7 / 37
Q9Y253 DNA polymerase eta Enzyme C00000555 C00000674 1 / 1
P49841 Glycogen synthase kinase-3 beta Gsk C00000555 C00000674 0 / 0
P02545 Prelamin-A/C Unclassified protein C00000555 C00000674 11 / 10
Q13951 Core-binding factor subunit beta Unclassified protein C00000555 C00000674 0 / 1
P38398 Breast cancer type 1 susceptibility protein Enzyme C00000568 C00000674 4 / 2
P10828 Thyroid hormone receptor beta NR1A2 C00000555 C00000674 3 / 1
O75496 Geminin Unclassified protein C00000555 C00000674 0 / 0
P39748 Flap endonuclease 1 Enzyme C00000555 C00000674 0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00000555 C00000674 0 / 0
Q01196 Runt-related transcription factor 1 Unclassified protein C00000555 C00000674 1 / 4
Q9Y3R4 Sialidase-2 Enzyme C00000555 C00000674 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00000555 C00000568 2 / 3
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00000555 C00000674 1 / 0
P54132 Bloom syndrome protein Enzyme C00000555 C00000674 1 / 2
P24941 Cyclin-dependent kinase 2 Cdc2 C00000555 C00000674 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000555 C00000674 0 / 1
Q99549 M-phase phosphoprotein 8 Unclassified protein C00000555 0 / 0
Q00535 Cyclin-dependent kinase 5 Cdk5 C00000674 0 / 0
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family C00000674 0 / 0
P49327 Fatty acid synthase Transferase C00000674 0 / 0
P51570 Galactokinase Enzyme C00000674 1 / 1
Q9HC97 G-protein coupled receptor 35 Kynurenic acid receptor C00000674 0 / 0
P08183 Multidrug resistance protein 1 drug C00000674 1 / 0
P15311 Ezrin Unclassified protein C00000555 0 / 1
P11387 DNA topoisomerase 1 Isomerase C00000674 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00000674 0 / 0
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00000674 0 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00000674 0 / 0
O75582 Ribosomal protein S6 kinase alpha-5 CAMK serine/threonine protein kinase MSKB subfamily C00000555 0 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim C00000674 0 / 0
O15296 Arachidonate 15-lipoxygenase B Enzyme C00000674 0 / 0
Q00534 Cyclin-dependent kinase 6 CMGC serine/threonine protein kinase family C00000674 1 / 0
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00000674 1 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00000674 1 / 1
P09769 Tyrosine-protein kinase Fgr Src C00000555 0 / 0
P68400 Casein kinase II subunit alpha Ck2 C00000555 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00000674 2 / 0
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00000555 0 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme C00000555 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00000674 1 / 1
P54855 UDP-glucuronosyltransferase 2B15 Enzyme C00000555 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00000555 0 / 1
P10145 Interleukin-8 Secreted protein C00000555 0 / 0
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00000568 0 / 0
P08311 Cathepsin G S1A C00000555 0 / 0
Q15418 Ribosomal protein S6 kinase alpha-1 Rskb C00000555 0 / 0
O15264 Mitogen-activated protein kinase 13 p38 C00000555 0 / 0
P09874 Poly [ADP-ribose] polymerase 1 Enzyme C00000674 0 / 0
P03956 Interstitial collagenase M10A C00000674 0 / 1
O95271 Tankyrase-1 Enzyme C00000674 0 / 0
P11308 Transcriptional regulator ERG Unclassified protein C00000555 1 / 2
P83916 Chromobox protein homolog 1 Unclassified protein C00000555 0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00000555 0 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein C00000674 0 / 0
P28907 ADP-ribosyl cyclase 1 Enzyme C00000674 0 / 1
O14757 Serine/threonine-protein kinase Chk1 Chk1 C00000555 0 / 0
P14679 Tyrosinase Oxidoreductase C00000674 4 / 2
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00000555 5 / 3
Q9H244 P2Y purinoceptor 12 Purine receptor C00000555 1 / 1
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00000674 4 / 4
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00000555 0 / 0
P06276 Cholinesterase Hydrolase C00000674 0 / 0
P06280 Alpha-galactosidase A Enzyme C00000674 1 / 1
P04745 Alpha-amylase 1 Enzyme C00000674 0 / 0
P45452 Collagenase 3 M10A C00000674 1 / 1
P49137 MAP kinase-activated protein kinase 2 CAMK serine/threonine protein kinase MAPKAPK C00000555 0 / 0
P18054 Arachidonate 12-lipoxygenase, 12S-type Enzyme C00000674 2 / 0
Q96RI1 Bile acid receptor NR1H4 C00000555 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00000674 2 / 2
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000674 0 / 0
P08253 72 kDa type IV collagenase M10A C00000674 1 / 3
Q9Y4K4 Mitogen-activated protein kinase kinase kinase kinase 5 STE serine/threonine protein kinase KHS subfamily C00000555 0 / 0
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00000555 0 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00000674 2 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00000674 2 / 2
O15118 Niemann-Pick C1 protein Unclassified protein C00000555 1 / 1
P39900 Macrophage metalloelastase M10A C00000674 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00000674 0 / 0
Q9HAW9 UDP-glucuronosyltransferase 1-8 Enzyme C00000555 0 / 0
Q9H2K2 Tankyrase-2 Enzyme C00000674 0 / 0
O14763 Tumor necrosis factor receptor superfamily member 10B Unclassified protein C00000674 1 / 0
P17252 Protein kinase C alpha type Alpha C00000555 0 / 0
P22303 Acetylcholinesterase Hydrolase C00000674 1 / 0
Q8IW41 MAP kinase-activated protein kinase 5 CAMK serine/threonine protein kinase MAPKAPK C00000555 0 / 0
O75116 Rho-associated protein kinase 2 Rock C00000555 0 / 0
P07948 Tyrosine-protein kinase Lyn Src C00000555 0 / 0
P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Enzyme C00000555 9 / 1
P31749 RAC-alpha serine/threonine-protein kinase Akt C00000555 4 / 1
O00141 Serine/threonine-protein kinase Sgk1 AGC serine/threonine protein kinase SGK subfamily C00000555 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00000674 1 / 1
P41240 Tyrosine-protein kinase CSK Csk C00000555 0 / 0
O75365 Protein tyrosine phosphatase type IVA 3 Tyr C00000555 0 / 0
P04062 Glucosylceramidase Enzyme C00000674 6 / 4
Q15046 Lysine--tRNA ligase Enzyme C00000674 2 / 1
O15530 3-phosphoinositide-dependent protein kinase 1 Pdk1 C00000555 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00000555 0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00000555 5 / 1
Q15759 Mitogen-activated protein kinase 11 p38 C00000555 0 / 0
P23443 Ribosomal protein S6 kinase beta-1 p70 C00000555 0 / 0
P19224 UDP-glucuronosyltransferase 1-6 Enzyme C00000555 0 / 0
P08246 Neutrophil elastase S1A C00000555 2 / 1
O43451 Maltase-glucoamylase, intestinal Hydrolase C00000555 0 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00000555 2 / 2
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00000674 0 / 3
Q04760 Lactoylglutathione lyase Enzyme C00000674 0 / 0
P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 Ampk C00000555 0 / 0
P35869 Aryl hydrocarbon receptor Transcription Factor C00000555 0 / 0
P43405 Tyrosine-protein kinase SYK Syk C00000555 0 / 0
P08254 Stromelysin-1 M10A C00000674 1 / 0
Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A CMGC dual-specificity kinase DYRK1 C00000555 1 / 0
P53778 Mitogen-activated protein kinase 12 p38 C00000555 0 / 0
P27338 Amine oxidase [flavin-containing] B Oxidoreductase C00000674 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00000555 2 / 0
Q99700 Ataxin-2 Unclassified protein C00000674 1 / 1
P40225 Thrombopoietin Unclassified protein C00000555 1 / 1
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme C00000555 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00000674 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00000674 4 / 1
Q9NPH5 NADPH oxidase 4 Enzyme C00000674 0 / 0
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00000555 3 / 0
Q02750 Dual specificity mitogen-activated protein kinase kinase 1 Ste7 C00000555 1 / 1
P45983 Mitogen-activated protein kinase 8 Jnk C00000555 0 / 0
P53779 Mitogen-activated protein kinase 10 Jnk C00000555 0 / 1
P45984 Mitogen-activated protein kinase 9 Jnk C00000555 0 / 0
O95067 G2/mitotic-specific cyclin-B2 Other cytosolic protein C00000674 0 / 0
P14635 G2/mitotic-specific cyclin-B1 Other cytosolic protein C00000674 0 / 0
P06493 Cyclin-dependent kinase 1 Cdc2 C00000674 0 / 0
Q8WWL7 G2/mitotic-specific cyclin-B3 Other cytosolic protein C00000674 0 / 0
P22694 cAMP-dependent protein kinase catalytic subunit beta Pka C00000555 0 / 0
P17612 cAMP-dependent protein kinase catalytic subunit alpha Pka C00000555 0 / 0
P22612 cAMP-dependent protein kinase catalytic subunit gamma Pka C00000555 0 / 0
P49840 Glycogen synthase kinase-3 alpha Gsk C00000674 0 / 0
P09619 Platelet-derived growth factor receptor beta Pdgfr C00000555 5 / 1
P16234 Platelet-derived growth factor receptor alpha Pdgfr C00000555 2 / 1
Q9HCP0 Casein kinase I isoform gamma-1 Ck1 C00000555 0 / 0
P48730 Casein kinase I isoform delta Ck1 C00000555 1 / 0
P49674 Casein kinase I isoform epsilon Ck1 C00000555 0 / 0
P78368 Casein kinase I isoform gamma-2 Ck1 C00000555 0 / 0
P48729 Casein kinase I isoform alpha Ck1 C00000555 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00000674 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00000674 2 / 1

134 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
196 AHR, bHLHe76 aryl hydrocarbon receptor C00000555 C00000568 C00000674
3727 JUND, AP-1 jun D proto-oncogene C00000555 C00000674
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00000555 C00000674
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00000555 C00000674
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00000555 C00000674
54658 UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) C00000555 C00000674
2100 ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 estrogen receptor 2 (ER beta) C00000555 C00000674
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 estrogen receptor 1 C00000555 C00000674
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00000555 C00000674
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00000555 C00000674
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00000674
10987 COPS5, CSN5, JAB1, MOV-34, SGN5 COP9 signalosome subunit 5 C00000555
1509 CTSD, CLN10, CPSD cathepsin D (EC:3.4.23.5) C00000555
1019 CDK4, CMM3, PSK-J3 cyclin-dependent kinase 4 (EC:2.7.11.22) C00000555
8621 CDK13, CDC2L, CDC2L5, CHED, hCDK13 cyclin-dependent kinase 13 (EC:2.7.11.23 2.7.11.22) C00000555
1719 DHFR, DHFRP1, DYR dihydrofolate reductase (EC:1.5.1.3) C00000555
3337 DNAJB1, HSPF1, Hdj1, Hsp40, RSPH16B, Sis1 DnaJ (Hsp40) homolog, subfamily B, member 1 C00000555
1875 E2F5, E2F-5 E2F transcription factor 5, p130-binding C00000555
9538 EI24, EPG4, PIG8, TP53I8 etoposide induced 2.4 C00000555
1967 EIF2B1, EIF2B, EIF2BA eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa C00000555
9133 CCNB2, HsT17299 cyclin B2 C00000555
821 CANX, CNX, IP90, P90 calnexin C00000555
2308 FOXO1, FKH1, FKHR, FOXO1A forkhead box O1 C00000555
2620 GAS2 growth arrest-specific 2 C00000555
2876 GPX1, GPXD, GSHPX1 glutathione peroxidase 1 (EC:1.11.1.9) C00000555
2947 GSTM3, GST5, GSTB, GSTM3-3, GTM3 glutathione S-transferase mu 3 (brain) (EC:2.5.1.18) C00000555
2950 GSTP1, DFN7, FAEES3, GST3, GSTP, PI glutathione S-transferase pi 1 (EC:2.5.1.18) C00000555
3014 H2AFX, H2A.X, H2A/X, H2AX H2A histone family, member X C00000555
3440 IFNA2, IFN-alphaA, IFNA, IFNA2B, INFA2 interferon, alpha 2 C00000555
3708 ITPR1, INSP3R1, IP3R, IP3R1, SCA15, SCA16, SCA29 inositol 1,4,5-trisphosphate receptor, type 1 C00000555
51283 BFAR, BAR, RNF47 bifunctional apoptosis regulator C00000555
3880 KRT19, CK19, K19, K1CS keratin 19 C00000555
23499 MACF1, ABP620, ACF7, MACF, OFC4 microtubule-actin crosslinking factor 1 C00000555
1432 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA mitogen-activated protein kinase 14 (EC:2.7.11.24) C00000555
4137 MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU microtubule-associated protein tau C00000555
9529 BAG5, BAG-5 BCL2-associated athanogene 5 C00000555
5082 PDCL, PhLP phosducin-like C00000555
5289 PIK3C3, VPS34, hVps34 phosphatidylinositol 3-kinase, catalytic subunit type 3 (EC:2.7.1.137) C00000555
8493 PPM1D, PP2C-DELTA, WIP1 protein phosphatase, Mg2+/Mn2+ dependent, 1D (EC:3.1.3.16) C00000555
9588 PRDX6, 1-Cys, AOP2, NSGPx, PRX, aiPLA2, p29 peroxiredoxin 6 (EC:1.11.1.9 1.11.1.15) C00000555
5580 PRKCD, MAY1, PKCD, nPKC-delta protein kinase C, delta (EC:2.7.10.2 2.7.11.13) C00000555
51495 PTPLAD1, B-IND1, HACD3, HSPC121 protein tyrosine phosphatase-like A domain containing 1 (EC:4.2.1.134) C00000555
5894 RAF1, CRAF, NS5, Raf-1, c-Raf v-raf-1 murine leukemia viral oncogene homolog 1 (EC:2.7.11.1) C00000555
5925 RB1, OSRC, RB, p105-Rb, pRb, pp110 retinoblastoma 1 C00000555
5955 RCN2, E6BP, ERC-55, ERC55, TCBP49 reticulocalbin 2, EF-hand calcium binding domain C00000555
387 RHOA, ARH12, ARHA, RHO12, RHOH12 ras homolog family member A C00000555
6093 ROCK1, P160ROCK, ROCK-I Rho-associated, coiled-coil containing protein kinase 1 (EC:2.7.11.1) C00000555
9475 ROCK2, ROCK-II Rho-associated, coiled-coil containing protein kinase 2 (EC:2.7.11.1) C00000555
10055 SAE1, AOS1, HSPC140, SUA1, UBLE1A SUMO1 activating enzyme subunit 1 C00000555
5054 SERPINE1, PAI, PAI-1, PAI1, PLANH1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 C00000555
6489 ST8SIA1, GD3S, SIAT8, SIAT8-A, SIAT8A, ST8SiaI ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 (EC:2.4.99.8) C00000555
10963 STIP1, HOP, IEF-SSP-3521, P60, STI1, STI1L stress-induced-phosphoprotein 1 C00000555
55578 SUPT20H, C13, C13orf19, FAM48A, P38IP, SPT20 suppressor of Ty 20 homolog (S. cerevisiae) C00000555
51347 TAOK3, DPK, JIK, MAP3K18 TAO kinase 3 (EC:2.7.11.1) C00000555
6903 TBCC, CFC tubulin folding cofactor C C00000555
472 ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1 ataxia telangiectasia mutated (EC:2.7.11.1) C00000555
7153 TOP2A, TOP2, TP2A topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) C00000555
7186 TRAF2, MGC:45012, TRAP, TRAP3 TNF receptor-associated factor 2 C00000555
10381 TUBB3, CDCBM, CDCBM1, CFEOM3A, TUBB4, beta-4 tubulin, beta 3 class III C00000555
54957 TXNL4B, DLP, Dim2 thioredoxin-like 4B C00000555
7296 TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR thioredoxin reductase 1 (EC:1.8.1.9) C00000555
58 ACTA1, ACTA, ASMA, CFTD, CFTD1, CFTDM, MPFD, NEM1, NEM2, NEM3 actin, alpha 1, skeletal muscle C00000555
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00000555
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00000555
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00000555
54600 UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) C00000555
7366 UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) C00000555
7416 VDAC1, PORIN, VDAC-1 voltage-dependent anion channel 1 C00000555
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00000674
9429 ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1 ATP-binding cassette, sub-family G (WHITE), member 2 C00000674
177 AGER, RAGE advanced glycosylation end product-specific receptor C00000674
581 BAX, BCL2L4 BCL2-associated X protein C00000674
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00000674
598 BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS BCL2-like 1 C00000674
329 BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 baculoviral IAP repeat containing 2 C00000674
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00000674
840 CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) C00000674
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00000674
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00000674
847 CAT catalase (EC:1.11.1.6) C00000674
890 CCNA2, CCN1, CCNA cyclin A2 C00000674
891 CCNB1, CCNB cyclin B1 C00000674
958 CD40, Bp50, CDW40, TNFRSF5, p50 CD40 molecule, TNF receptor superfamily member 5 C00000674
972 CD74, DHLAG, HLADG, II, Ia-GAMMA CD74 molecule, major histocompatibility complex, class II invariant chain C00000674
983 CDK1, CDC2, CDC28A, P34CDC2 cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) C00000674
1017 CDK2, p33(CDK2) cyclin-dependent kinase 2 (EC:2.7.11.22) C00000674
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00000674
1027 CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 cyclin-dependent kinase inhibitor 1B (p27, Kip1) C00000674
1031 CDKN2C, INK4C, p18, p18-INK4C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) C00000674
1437 CSF2, GMCSF colony stimulating factor 2 (granulocyte-macrophage) C00000674
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00000674
1577 CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3 cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1) C00000674
1950 EGF, HOMG4, URG epidermal growth factor C00000674
1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA epidermal growth factor receptor (EC:2.7.10.1) C00000674
1958 EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225 early growth response 1 C00000674
2203 FBP1, FBP fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) C00000674
2353 FOS, AP-1, C-FOS, p55 FBJ murine osteosarcoma viral oncogene homolog C00000674
2354 FOSB, AP-1, G0S3, GOS3, GOSB FBJ murine osteosarcoma viral oncogene homolog B C00000674
4616 GADD45B, GADD45BETA, MYD118 growth arrest and DNA-damage-inducible, beta C00000674
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00000674
1951 CELSR3, CDHF11, EGFL1, FMI1, HFMI1, MEGF2, RESDA1 cadherin, EGF LAG seven-pass G-type receptor 3 C00000555
3565 IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 interleukin 4 C00000674
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00000674
3726 JUNB, AP-1 jun B proto-oncogene C00000674
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00000674
5602 MAPK10, JNK3, JNK3A, PRKM10, SAPK1b, p493F12, p54bSAPK mitogen-activated protein kinase 10 (EC:2.7.11.24) C00000674
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00000674
5599 MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c mitogen-activated protein kinase 8 (EC:2.7.11.24) C00000674
5601 MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK mitogen-activated protein kinase 9 (EC:2.7.11.24) C00000674
4312 MMP1, CLG, CLGN matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) C00000674
4318 MMP9, CLG4B, GELB, MANDP2, MMP-9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) C00000674
4790 NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 C00000674
4793 NFKBIB, IKBB, TRIP9 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta C00000674
9572 NR1D1, EAR1, THRA1, THRAL, ear-1, hRev nuclear receptor subfamily 1, group D, member 1 C00000674
5347 PLK1, PLK, STPK13 polo-like kinase 1 (EC:2.7.11.21) C00000674
8000 PSCA, PRO232 prostate stem cell antigen C00000674
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00000674
5747 PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK protein tyrosine kinase 2 (EC:2.7.10.2) C00000674
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00000674
6401 SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 selectin E C00000674
2810 SFN, YWHAS stratifin C00000674
6647 SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer superoxide dismutase 1, soluble (EC:1.15.1.1) C00000674
29110 TBK1, NAK, T2K TANK-binding kinase 1 (EC:2.7.11.1) C00000674
7128 TNFAIP3, A20, OTUD7C, TNFA1P2 tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) C00000674
8743 TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL tumor necrosis factor (ligand) superfamily, member 10 C00000674
9540 TP53I3, PIG3 tumor protein p53 inducible protein 3 C00000674
8626 TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L tumor protein p63 C00000674
7161 TP73, P73 tumor protein p73 C00000674
54659 UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) C00000674
10451 VAV3 vav 3 guanine nucleotide exchange factor C00000674
7412 VCAM1, CD106, INCAM-100 vascular cell adhesion molecule 1 C00000674
7422 VEGFA, MVCD1, VEGF, VPF vascular endothelial growth factor A C00000674
8839 WISP2, CCN5, CT58, CTGF-L WNT1 inducible signaling pathway protein 2 C00000674
331 XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 X-linked inhibitor of apoptosis C00000674

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (130)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#615224 Advanced sleep phase syndrome, familial, 2; fasps2 P48730
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#615007 Basal ganglia calcification, idiopathic, 4; ibgc4 P09619
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#609821 Bleeding disorder, platelet-type, 8; bdplt8 Q9H244
#614490 Blood group, junior system; jr Q9UNQ0
#210900 Bloom syndrome; blm P54132
%606641 Body mass index; bmi P37231
#114480 Breast cancer P31749
P38398
P42336
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#300615 Brunner syndrome P21397
#615279 Cardiofaciocutaneous syndrome 3; cfc3 Q02750
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#609338 Carotid intimal medial thickness 1 P37231
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#613641 Charcot-marie-tooth disease, recessive intermediate b; cmtrib Q15046
#114500 Colorectal cancer; crc P18054
P31749
P42336
P84022
Q14191
#612918 Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi P42336
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#615108 Cowden syndrome 5; cws5 P42336
#615109 Cowden syndrome 6; cws6 P31749
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#162800 Cyclic neutropenia P08246
#613916 Deafness, autosomal recessive 89; dfnb89 Q15046
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#133239 Esophageal cancer P04637
P18054
#615363 Estrogen resistance; estrr P03372
#612219 Ewing sarcoma; es P11308
#301500 Fabry disease P06280
#600274 Frontotemporal dementia; ftd P10636
#230200 Galactokinase deficiency P51570
#606764 Gastrointestinal stromal tumor; gist P16234
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#143500 Gilbert syndrome P22309
P22310
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#137800 Glioma susceptibility 1; glm1 P37231
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#114550 Hepatocellular carcinoma P42336
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#607685 Hypereosinophilic syndrome, idiopathic; hes P16234
#145000 Hyperparathyroidism 1; hrpt1 O00255
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#612244 Inflammatory bowel disease 13; ibd13 P08183
#603932 Intervertebral disc disease; idd P14780
#607785 Juvenile myelomonocytic leukemia; jmml P09619
#182000 Keratosis, seborrheic P42336
#601626 Leukemia, acute myeloid; aml P09619
P36888
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P04637
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#602501 Megalencephaly-capillary malformation-polymicrogyria syndrome; mcap P42336
#603387 Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome; mpph P42336
#614104 Mental retardation, autosomal dominant 7; mrd7 Q13627
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#131440 Myeloproliferative disorder, chronic, with eosinophilia P09619
#228550 Myofibromatosis, infantile, 1; imf1 P09619
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#257220 Niemann-pick disease, type c1; npc1 O15118
#601665 Obesity P37231
#167000 Ovarian cancer P38398
P42336
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#604229 Peters anomaly Q16678
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#176920 Proteus syndrome P31749
#275210 Restrictive dermopathy, lethal P02545
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#609620 Short qt syndrome 1; sqt1 Q12809
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#602111 Spondyloepimetaphyseal dysplasia, missouri type P45452
#275355 Squamous cell carcinoma, head and neck; hnscc O14763
P04637
%612223 Stature quantitative trait locus 11; stqtl11 Q00534
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#187950 Thrombocythemia 1; thcyt1 P40225
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#277700 Werner syndrome; wrn Q14191
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253
#112100 Yt blood group antigen P22303

KEGG DISEASE (110)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q15046 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P37231 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04637 (related)
Q92731 (marker)
H00028 Choriocarcinoma P03956 (related)
P04637 (related)
P08253 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
Q01196 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
P28907 (marker)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P08253 (related)
P14780 (related)
P35354 (related)
H00027 Ovarian cancer P04637 (related)
P38398 (related)
P42336 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
P38398 (related)
H00032 Thyroid cancer P04637 (related)
P37231 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
P15311 (marker)
H00038 Malignant melanoma P04637 (related)
P14679 (marker)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
P09619 (related)
P16234 (related)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
P35354 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00125 Fabry disease P06280 (related)
H00100 Neutropenic disorders P08246 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00024 Prostate cancer P10275 (related)
P11308 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00035 Ewing's sarcoma P11308 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00479 Metaphyseal dysplasias P14780 (related)
P45452 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00548 Brunner syndrome P21397 (related)
H00208 Hyperbilirubinemia P22309 (related)
H00539 PTEN hamartoma tumor syndrome (PHTS) P31749 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00409 Type II diabetes mellitus P37231 (related)
H00227 Congenital amegakaryocytic thrombocytopenia (CAMT) P40225 (marker)
H00192 Xanthinuria P47989 (related)
H00070 Galactosemia P51570 (related)
H00606 Early infantile epileptic encephalopathy P53779 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
Q14191 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00523 Noonan syndrome and related disorders Q02750 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H01235 Bleeding disorder platelet-type Q9H244 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

15 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D001249 Asthma C00000555
D004802 Eosinophilia C00000555
D005317 Fetal Growth Retardation C00000555
D005327 Fetal Resorption C00000555
D020567 Fetal Weight C00000555
D005355 Fibrosis C00000555
D015459 Leukemia-Lymphoma, Adult T-Cell C00000555
D008106 Liver Cirrhosis, Experimental C00000555
D010922 Placenta Diseases C00000555
D009202 Cardiomyopathies C00000674
D002386 Cataract C00000674
D005483 Flushing C00000674
D006529 Hepatomegaly C00000674
D008103 Liver Cirrhosis C00000674
D010051 Ovarian Neoplasms C00000674