Comptonia peregrina
Species
KNApSAcK Entry
| Organism name | Comptonia peregrina |
|---|---|
| Genus | Comptonia |
| Family | Myricaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Comptonia peregrina |
|---|---|
| Linked NCBI taxonomy ID | 29742 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Myricaceae |
|---|---|
| ID | 26766 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Natural Activity
List (4)
| Species | Activity |
|---|---|
| Comptonia peregrina (L.) J. M. Coult. | Astringent |
| Comptonia peregrina (L.) J. M. Coult. | Depurative |
| Comptonia peregrina (L.) J. M. Coult. | Expectorant |
| Comptonia peregrina (L.) J. M. Coult. | Tonic |
Metabolite list (11)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00004536
|
Izalpinin
/ 7-O-Methylgalangin / Galangin 7-methyl ether / 3,5-Dihydroxy-7-methoxyflavone / 3,5-Dihydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one |
CHEMBL464966
|
No. 3 | No. 15 |
|
|||
|
C00008164
|
Comptonin
|
No. 25 | No. 14 |
|
||||
|
C00008166
|
Cryptostrobin
|
CHEMBL1269161
|
No. 25 | No. 14 |
|
|||
|
C00003795
|
Tectochrysin
/ 5-hydroxy-7-methoxyflavone |
CHEMBL164841
|
12 / 19 / 14 | No. 76 | No. 15 |
|
||
|
C00007998
|
Angoletin
|
CHEMBL452234
|
C105002
|
No. 90 | No. 13 |
|
||
|
C00007997
|
Myrigalon B
|
No. 90 | No. 13 |
|
||||
|
C00008731
|
(2R,3R)-Pinobanksin 3-acetate
|
CHEMBL1094265
|
No. 301 | No. 14 |
|
|||
|
C00007042
|
Stercurensin
|
CHEMBL1271362
|
No. 1043 |
|
||||
|
C00007041
|
Triangularin
|
No. 1043 |
|
|||||
|
C00007040
|
Aurentiacin A
|
No. 1043 |
|
|||||
|
C00007044
|
2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone
|
CHEMBL463095
|
No. 1043 |
|
Human Protein / Gene in interactions
12 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P04062 | Glucosylceramidase | Enzyme | C00003795 | 6 / 4 |
| P37840 | Alpha-synuclein | Unclassified protein | C00003795 | 4 / 2 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00003795 | 3 / 2 |
| P08183 | Multidrug resistance protein 1 | drug | C00003795 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00003795 | 0 / 1 |
| O75496 | Geminin | Unclassified protein | C00003795 | 0 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00003795 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00003795 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00003795 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003795 | 0 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00003795 | 4 / 3 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00003795 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (19)
| OMIM | preferred title | UniProt |
|---|---|---|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
P37840 |
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
KEGG DISEASE (14)
| KEGG | name | UniProt |
|---|---|---|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
P37840 (related) |
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|