Species

KNApSAcK Entry

Organism name Artocarpus champeden Spreng.
Genus Artocarpus
Family Moraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Artocarpus
Linked NCBI taxonomy ID 3488
Linked level genus

Family

Family in NCBI taxonomy Moraceae
ID 3487

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (18)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00030075 External link 512 Cyclocommunin
CHEMBL485976
No. 14 No. 15
C00004032 External link 512 Artocarpin
/ 2',4',5-Trihydroxy-7-methoxy-6-(3-methyl-1-butenyl)-3-(3-methyl-2-butenyl)flavone
/ 2-(2,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-6-(3-methyl-1-butenyl)-3-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
No. 14 No. 15
C00004062 External link 512 Isoartocarpin
/ Cycloartocarpin
No. 14 No. 15
C00013412 External link 512 Cudraflavone C
/ 2',4',5,7-Tetrahydroxy-3,6-bis(3-methyl-2-butenyl)flavone
/ 2-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-3,6-bis(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
CHEMBL485777
No. 14 No. 15
C00004102 External link 512 Cyclocommunol
/ 3,8,10-Trihydroxy-6-(2-methyl-1-propenyl)-6H,7H-[1]benzopyrano[4,3-b][1]benzopyran-7-one
No. 15 No. 15
C00029567 External link 512 5'-Hydroxycudraflavone A
No. 18 No. 15
C00008362 External link 512 Artocarpanone
CHEMBL467194
No. 25 No. 14
C00029738 External link 512 Artonin B
CHEMBL462877
No. 44
C00013460 External link 512 Heterophyllin
CHEMBL461821
No. 44
C00029736 External link 512 Artoindonesianin V
No. 44
C00004064 External link 512 Cycloheterophyllin
CHEMBL461820
C107099
5 / 2 / 2 No. 44
C00029737 External link 512 Artonin A
CHEMBL516550
No. 44
C00029735 External link 512 Artoindonesianin U
No. 44
C00003859 External link 512 Norartocarpetin
CHEMBL463145
3 / 0 / 3 No. 71 No. 15
C00029730 External link 512 Artoindonesianin E
No. 77 No. 14
C00008535 External link 512 Heteroflavanone A
CHEMBL508961
No. 77 No. 14
C00023286 External link 512 Communol
/ Elliotinol
No. 165
C00029937 External link 512 Chaplasin
/ Chaplashin
No. 4175

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00003859 0 / 3
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00003859 0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme C00004064 2 / 2
O75496 Geminin Unclassified protein C00004064 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00004064 0 / 0
P56817 Beta-secretase 1 A1A C00003859 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00004064 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00004064 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405

KEGG DISEASE (5)

KEGG name UniProt
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)