Caragana frutex

• Index
• Plant Species
• Metabolite list (7)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Caragana frutex
Genus	Caragana
Family	Fabaceae
Kingdom	Plantae

---

NCBI taxonomy

Entry

Linked NCBI taxonomy name	Caragana frutex
Linked NCBI taxonomy ID	47643
Linked level	species

Family

Family in NCBI taxonomy	Fabaceae
ID	3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (7)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00004635	Isorhamnetin / 3'-O-Methylquercetin / 3,4',5,7-Tetrahydroxy-3'-methoxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one	CHEMBL379064	C047368	12 / 10 / 13	10 / 0	No. 3	No. 15
C00001071	Myricetin	CHEMBL164	C040015	78 / 70 / 56	39 / 2	No. 3	No. 15
C00002547	(-)-Medicarpin / 3-Hydroxy-9-methoxypterocarpan	CHEMBL238845 CHEMBL413297	C047353	3 / 1 / 1		No. 66	No. 15
C00002546	Inermin / Maackiain / (-)-Maackiain / Demethylpterocarpin / 3-Hydroxy-8,9-methylenedioxypterocarpan	CHEMBL334918 CHEMBL239047 CHEMBL445279		3 / 2 / 3		No. 66	No. 15
C00002499	Scopoletin	CHEMBL71851	D012603	48 / 37 / 34	9 / 0	No. 864	No. 25
C00000576	Xanthotoxin	CHEMBL416	D008730	104 / 55 / 45	22 / 18	No. 1282	No. 25
C00000575	Bergaptan	CHEMBL24171	C022909	22 / 22 / 17	0 / 3	No. 1282	No. 25

Human Protein / Gene in interactions

206 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000575 C00000576 C00001071 C00002499 C00002546	0 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000575 C00000576 C00001071 C00002499	1 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000575 C00000576 C00001071 C00002499	1 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000575 C00000576 C00001071 C00002499	0 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00000576 C00001071 C00002499 C00004635	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00001071 C00002499 C00004635	1 / 2
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000575 C00001071 C00002499	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00000575 C00000576 C00002499	7 / 3
P83916	Chromobox protein homolog 1	Unclassified protein	C00000575 C00000576 C00001071	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00000575 C00001071 C00002499	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00000576 C00001071 C00002499	0 / 3
O00255	Menin	Unclassified protein	C00001071 C00002499 C00004635	2 / 5
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00001071 C00002499 C00004635	1 / 1
P22303	Acetylcholinesterase	Hydrolase	C00000576 C00001071 C00002499	1 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000575 C00001071 C00002499	3 / 3
P56817	Beta-secretase 1	A1A	C00000575 C00000576	0 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00001071 C00002499	2 / 2
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00002499 C00004635	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00000576 C00001071	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00001071 C00004635	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00000575 C00002547	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00001071 C00002499	1 / 1
P04745	Alpha-amylase 1	Enzyme	C00001071 C00004635	0 / 0
Q16678	Cytochrome P450 1B1	Cytochrome P450 1B1	C00001071 C00004635	4 / 4
P10275	Androgen receptor	NR3C4	C00000575 C00000576	3 / 4
Q9UBT6	DNA polymerase kappa	Enzyme	C00001071 C00004635	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00001071 C00002499	0 / 0
P04062	Glucosylceramidase	Enzyme	C00001071 C00002499	6 / 4
P15121	Aldose reductase	Enzyme	C00001071 C00002499	0 / 0
O75496	Geminin	Unclassified protein	C00002499 C00002547	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00001071 C00004635	0 / 0
P29466	Caspase-1	C14	C00000576 C00002499	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00001071 C00002499	0 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00000575 C00000576	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00001071 C00002499	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00000576 C00001071	2 / 3
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00001071 C00002499	0 / 0
Q09470	Potassium voltage-gated channel subfamily A member 1	KCNA, Kv1.x (Shaker)	C00000575 C00000576	1 / 1
P20813	Cytochrome P450 2B6	Cytochrome P450 2B6	C00000575 C00000576	1 / 0
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00001071 C00004635	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00000576 C00002499	1 / 2
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00000576 C00002547	1 / 1
P16473	Thyrotropin receptor	Glycohormone receptor	C00000575 C00000576	3 / 2
Q01453	Peripheral myelin protein 22	Unclassified protein	C00001071	5 / 2
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00001071	0 / 0
P17658	Potassium voltage-gated channel subfamily A member 6	K	C00000575	0 / 0
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00000576	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00000576	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00000576	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00000576	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00000576	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00000576	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
P11309	Serine/threonine-protein kinase pim-1	Pim	C00001071	0 / 0
P28907	ADP-ribosyl cyclase 1	Enzyme	C00001071	0 / 1
P08183	Multidrug resistance protein 1	drug	C00000575	1 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00000576	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00000576	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00000576	0 / 0
Q8N1Q1	Carbonic anhydrase 13	Lyase	C00002499	0 / 0
P23443	Ribosomal protein S6 kinase beta-1	p70	C00000576	0 / 0
P04792	Heat shock protein beta-1	Unclassified protein	C00004635	2 / 1
P54132	Bloom syndrome protein	Enzyme	C00001071	1 / 2
Q9HC97	G-protein coupled receptor 35	Kynurenic acid receptor	C00001071	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00001071	1 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00000576	1 / 8
P11387	DNA topoisomerase 1	Isomerase	C00001071	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00001071	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00000576	2 / 2
P14416	D(2) dopamine receptor	Dopamine receptor	C00000576	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00000576	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00000576	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00000576	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00000576	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00000576	0 / 0
Q15746	Myosin light chain kinase, smooth muscle	Mlck	C00001071	1 / 1
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00000576	0 / 0
P16389	Potassium voltage-gated channel subfamily A member 2	KCNA, Kv1.x (Shaker)	C00000575	0 / 0
Q9Y3R4	Sialidase-2	Enzyme	C00001071	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00000576	1 / 1
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00001071	0 / 0
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00000576	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00000576	1 / 0
P04406	Glyceraldehyde-3-phosphate dehydrogenase	Enzyme	C00002499	0 / 0
O43570	Carbonic anhydrase 12	Lyase	C00002499	1 / 2
P36888	Receptor-type tyrosine-protein kinase FLT3	Pdgfr	C00001071	1 / 1
P27361	Mitogen-activated protein kinase 3	Erk	C00000576	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00000576	0 / 0
P42336	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Enzyme	C00001071	9 / 1
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00002499	0 / 0
P43166	Carbonic anhydrase 7	Lyase	C00002499	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00002499	0 / 0
P54855	UDP-glucuronosyltransferase 2B15	Enzyme	C00002499	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00000576	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00000576	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00000576	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00000576	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00000576	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00000576	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00000576	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00002499	1 / 1
P25101	Endothelin-1 receptor	Endothelin receptor	C00000576	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00000576	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00000576	1 / 0
P00915	Carbonic anhydrase 1	Lyase	C00002499	0 / 0
Q14790	Caspase-8	C14	C00001071	2 / 1
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00000576	0 / 0
P08311	Cathepsin G	S1A	C00000576	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00000576	1 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00000576	0 / 0
P03956	Interstitial collagenase	M10A	C00000576	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00000576	0 / 0
P22001	Potassium voltage-gated channel subfamily A member 3	KCNA, Kv1.x (Shaker)	C00000575	0 / 0
Q04206	Transcription factor p65	Transcription Factor	C00002499	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00001071	1 / 1
P09923	Intestinal-type alkaline phosphatase	Enzyme	C00001071	0 / 0
P05186	Alkaline phosphatase, tissue-nonspecific isozyme	Enzyme	C00001071	3 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00001071	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00000576	0 / 0
P06746	DNA polymerase beta	Enzyme	C00001071	0 / 0
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00001071	0 / 0
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00000576	1 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00001071	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00000576	0 / 1
P06213	Insulin receptor	TK tyrosine-protein kinase INSR subfamily	C00001071	5 / 4
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00000576	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00000576	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00001071	2 / 2
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00000576	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00000576	2 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00000576	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00000576	1 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00000576	0 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00000576	0 / 0
P06276	Cholinesterase	Hydrolase	C00001071	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00000576	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00000576	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00000576	0 / 0
P06280	Alpha-galactosidase A	Enzyme	C00002499	1 / 1
P33765	Adenosine receptor A3	Adenosine receptor	C00000576	0 / 0
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00001071	2 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00000576	1 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00000576	0 / 0
P10696	Alkaline phosphatase, placental-like	Enzyme	C00001071	0 / 1
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00000576	2 / 1
P08246	Neutrophil elastase	S1A	C00000576	2 / 1
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00000576	2 / 2
Q16790	Carbonic anhydrase 9	Lyase	C00002499	0 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00001071	2 / 0
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00001071	1 / 1
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00002499	0 / 0
P55789	FAD-linked sulfhydryl oxidase ALR	Enzyme	C00002499	1 / 0
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00000576	0 / 0
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00002499	0 / 0
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00002499	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00000576	0 / 0
P03372	Estrogen receptor	NR3A1	C00000576	1 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00000576	1 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00000576	0 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00000576	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00000576	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00000576	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00000576	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00000576	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00000576	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00000576	0 / 0
Q00796	Sorbitol dehydrogenase	Enzyme	C00002499	0 / 0
Q02880	DNA topoisomerase 2-beta	Isomerase	C00001071	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00001071	0 / 0
P55210	Caspase-7	C14	C00002499	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00001071	0 / 0
P31941	DNA dC->dU-editing enzyme APOBEC-3A	Enzyme	C00001071	0 / 0
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00000576	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00001071	0 / 0
Q15046	Lysine--tRNA ligase	Enzyme	C00001071	2 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00001071	0 / 0
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00000576	1 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00002499	5 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00001071	4 / 3
Q99549	M-phase phosphoprotein 8	Unclassified protein	C00001071	0 / 0
P48547	Potassium voltage-gated channel subfamily C member 1	K	C00000575	0 / 0
O75795	UDP-glucuronosyltransferase 2B17	Enzyme	C00002499	1 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00000576	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00000576	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00000576	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00000576	1 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00000576	0 / 1
P22460	Potassium voltage-gated channel subfamily A member 5	KCNA, Kv1.x (Shaker)	C00000575	1 / 1
Q04760	Lactoylglutathione lyase	Enzyme	C00001071	0 / 0
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00000576	0 / 0
P31639	Sodium/glucose cotransporter 2	Glucose	C00002546	1 / 1
P13866	Sodium/glucose cotransporter 1	Glucose	C00002546	1 / 1
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00002499	0 / 0
P40225	Thrombopoietin	Unclassified protein	C00001071	1 / 1
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00002499	3 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00001071	1 / 1
P33527	Multidrug resistance-associated protein 1	drugs	C00001071	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00001071	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00001071	1 / 4
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001071	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00001071	2 / 1
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00001071	0 / 0
Q9HCT0	Fibroblast growth factor 22	Unclassified protein	C00001071	0 / 0

71 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00000576 C00001071 C00004635
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00000576 C00001071
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00001071 C00004635
581	BAX, BCL2L4	BCL2-associated X protein	C00000576 C00001071
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00000576 C00001071
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00000576 C00001071
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00000576 C00001071
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00001071 C00004635
1553	CYP2A13, CPAD, CYP2A, CYPIIA13	cytochrome P450, family 2, subfamily A, polypeptide 13 (EC:1.14.14.1)	C00000576
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00001071
1031	CDKN2C, INK4C, p18, p18-INK4C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	C00001071
1312	COMT	catechol-O-methyltransferase (EC:2.1.1.6)	C00001071
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00001071
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00001071
847	CAT	catalase (EC:1.11.1.6)	C00001071
397	ARHGDIB, D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2	Rho GDP dissociation inhibitor (GDI) beta	C00001071
1786	DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT	DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37)	C00001071
54583	EGLN1, C1orf12, ECYT3, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6	egl-9 family hypoxia-inducible factor 1 (EC:1.14.11.29)	C00001071
2203	FBP1, FBP	fructose-1,6-bisphosphatase 1 (EC:3.1.3.11)	C00001071
3082	HGF, DFNB39, F-TCF, HGFB, HPTA, SF	hepatocyte growth factor (hepapoietin A; scatter factor)	C00001071
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00001071
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00001071
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00001071
4233	MET, AUTS9, HGFR, RCCP2, c-Met	met proto-oncogene (EC:2.7.10.1)	C00001071
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00001071
4609	MYC, MRTL, MYCC, bHLHe39, c-Myc	v-myc avian myelocytomatosis viral oncogene homolog	C00001071
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00001071
8505	PARG, PARG99	poly (ADP-ribose) glycohydrolase (EC:3.2.1.143)	C00001071
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00001071
8000	PSCA, PRO232	prostate stem cell antigen	C00001071
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00001071
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00001071
23411	SIRT1, SIR2L1	sirtuin 1	C00001071
6513	SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED	solute carrier family 2 (facilitated glucose transporter), member 1	C00001071
1244	ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	C00001071
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00001071
9540	TP53I3, PIG3	tumor protein p53 inducible protein 3	C00001071
8626	TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L	tumor protein p63	C00001071
7161	TP73, P73	tumor protein p73	C00001071
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00004635
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00004635
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00004635
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00004635
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00004635
4973	OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1	oxidized low density lipoprotein (lectin-like) receptor 1	C00004635
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00004635
8553	BHLHE40, BHLHB2, DEC1, HLHB2, SHARP-2, STRA13, Stra14	basic helix-loop-helix family, member e40	C00000576
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00000576
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00000576
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00000576
8824	CES2, CE-2, CES2A1, PCE-2, iCE	carboxylesterase 2 (EC:3.1.1.1 3.1.1.84 3.1.1.56)	C00000576
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00000576
891	CCNB1, CCNB	cyclin B1	C00001071
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00000576
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00000576
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00000576
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00000576
3034	HAL, HIS, HSTD	histidine ammonia-lyase (EC:4.3.1.3)	C00000576
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00000576
3355109			C00000576
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00000576
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00000576
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00002499
54575	UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J	UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17)	C00002499
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00002499
54578	UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F	UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17)	C00002499
54577	UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G	UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17)	C00002499
54576	UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H	UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17)	C00002499
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00002499
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00002499
7508	XPC, RAD4, XP3, XPCC	xeroderma pigmentosum, complementation group C	C00002499

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions